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Kenneth Durbin
Kenneth Durbin
Proteinaceous
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Year
Mapping intact protein isoforms in discovery mode using top-down proteomics
JC Tran, L Zamdborg, DR Ahlf, JE Lee, AD Catherman, KR Durbin, ...
Nature 480 (7376), 254-258, 2011
7462011
Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence
AD Catherman, KR Durbin, DR Ahlf, BP Early, RT Fellers, JC Tran, ...
Molecular & Cellular Proteomics 12 (12), 3465-3473, 2013
1822013
A protease for'middle-down'proteomics
C Wu, JC Tran, L Zamdborg, KR Durbin, M Li, DR Ahlf, BP Early, ...
Nature methods 9 (8), 822-824, 2012
1822012
Accurate sequence analysis of a monoclonal antibody by top-down and middle-down orbitrap mass spectrometry applying multiple ion activation techniques
L Fornelli, K Srzentić, R Huguet, C Mullen, S Sharma, V Zabrouskov, ...
Analytical chemistry 90 (14), 8421-8429, 2018
1332018
Analysis of intact protein isoforms by mass spectrometry
JD Tipton, JC Tran, AD Catherman, DR Ahlf, KR Durbin, NL Kelleher
Journal of Biological Chemistry 286 (29), 25451-25458, 2011
1322011
The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput
JF Kellie, JC Tran, JE Lee, DR Ahlf, HM Thomas, I Ntai, AD Catherman, ...
Molecular BioSystems 6 (9), 1532-1539, 2010
1312010
Multiplexed mass spectrometry of individual ions improves measurement of proteoforms and their complexes
JO Kafader, RD Melani, KR Durbin, B Ikwuagwu, BP Early, RT Fellers, ...
Nature methods 17 (4), 391-394, 2020
1262020
Quantitation and identification of thousands of human proteoforms below 30 kDa
KR Durbin, L Fornelli, RT Fellers, PF Doubleday, M Narita, NL Kelleher
Journal of proteome research 15 (3), 976-982, 2016
1192016
The first pilot project of the consortium for top‐down proteomics: a status report
X Dang, J Scotcher, S Wu, RK Chu, N Tolić, I Ntai, PM Thomas, RT Fellers, ...
Proteomics 14 (10), 1130-1140, 2014
1142014
Size-sorting combined with improved nanocapillary liquid chromatography− mass spectrometry for identification of intact proteins up to 80 kDa
A Vellaichamy, JC Tran, AD Catherman, JE Lee, JF Kellie, SMM Sweet, ...
Analytical chemistry 82 (4), 1234-1244, 2010
1132010
Potential mechanisms of target-independent uptake and toxicity of antibody-drug conjugates
PK Mahalingaiah, R Ciurlionis, KR Durbin, RL Yeager, BK Philip, B Bawa, ...
Pharmacology & Therapeutics 200, 110-125, 2019
1122019
A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome
JE Lee, JF Kellie, JC Tran, JD Tipton, AD Catherman, HM Thomas, ...
Journal of the American Society for Mass Spectrometry 20, 2183-2191, 2009
1092009
Top down proteomics of human membrane proteins from enriched mitochondrial fractions
AD Catherman, M Li, JC Tran, KR Durbin, PD Compton, BP Early, ...
Analytical chemistry 85 (3), 1880-1888, 2013
892013
Advancing top-down analysis of the human proteome using a benchtop quadrupole-orbitrap mass spectrometer
L Fornelli, KR Durbin, RT Fellers, BP Early, JB Greer, RD LeDuc, ...
Journal of proteome research 16 (2), 609-618, 2017
822017
An informatic framework for decoding protein complexes by top-down mass spectrometry
OS Skinner, PC Havugimana, NA Haverland, L Fornelli, BP Early, ...
Nature methods 13 (3), 237-240, 2016
762016
Kinetics of re-establishing H3K79 methylation marks in global human chromatin
SMM Sweet, M Li, PM Thomas, KR Durbin, NL Kelleher
Journal of biological chemistry 285 (43), 32778-32786, 2010
752010
Robust analysis of the yeast proteome under 50 kDa by molecular-mass-based fractionation and top-down mass spectrometry
JF Kellie, AD Catherman, KR Durbin, JC Tran, JD Tipton, JL Norris, ...
Analytical chemistry 84 (1), 209-215, 2012
672012
Intact mass detection, interpretation, and visualization to automate Top‐Down proteomics on a large scale
KR Durbin, JC Tran, L Zamdborg, SMM Sweet, AD Catherman, JE Lee, ...
Proteomics 10 (20), 3589-3597, 2010
582010
Analyzing internal fragmentation of electrosprayed ubiquitin ions during beam-type collisional dissociation
KR Durbin, OS Skinner, RT Fellers, NL Kelleher
Journal of the American Society for Mass Spectrometry 26 (5), 782-787, 2015
542015
STORI plots enable accurate tracking of individual ion signals
JO Kafader, SC Beu, BP Early, RD Melani, KR Durbin, V Zabrouskov, ...
Journal of The American Society for Mass Spectrometry 30, 2200-2203, 2019
532019
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