Neil P. Blackledge
Neil P. Blackledge
Post Doctoral Research Associate, University of Oxford
Verified email at
Cited by
Cited by
Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation
NP Blackledge, AM Farcas, T Kondo, HW King, JF McGouran, ...
Cell 157 (6), 1445-1459, 2014
KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands
AM Farcas, NP Blackledge, I Sudbery, HK Long, JF McGouran, NR Rose, ...
elife 1, e00205, 2012
Targeting Polycomb systems to regulate gene expression: modifications to a complex story
NP Blackledge, NR Rose, RJ Klose
Nature Reviews Molecular Cell Biology 16 (11), 643, 2015
CpG islands recruit a histone H3 lysine 36 demethylase
NP Blackledge, JC Zhou, MY Tolstorukov, AM Farcas, PJ Park, RJ Klose
Molecular cell 38 (2), 179-190, 2010
Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment
S Cooper, M Dienstbier, R Hassan, L Schermelleh, J Sharif, ...
Cell reports 7 (5), 1456-1470, 2014
ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection
HK Long, NP Blackledge, RJ Klose
Biochemical Society Transactions 41 (3), 727-740, 2013
Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates
HK Long, D Sims, A Heger, NP Blackledge, C Kutter, ML Wright, ...
Elife 2, e00348, 2013
CpG island chromatin: a platform for gene regulation
NP Blackledge, R Klose
Epigenetics 6 (2), 147-152, 2011
Chromatin sampling—an emerging perspective on targeting polycomb repressor proteins
RJ Klose, S Cooper, AM Farcas, NP Blackledge, N Brockdorff
PLoS genetics 9 (8), e1003717, 2013
Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus
CJ Ott, NP Blackledge, JL Kerschner, SH Leir, GE Crawford, CU Cotton, ...
Proceedings of the National Academy of Sciences, pnas. 0900946106, 2009
RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes
NR Rose, HW King, NP Blackledge, NA Fursova, KJI Ember, R Fischer, ...
Elife 5, e18591, 2016
The SET1 complex selects actively transcribed target genes via multivalent interaction with CpG island chromatin
DA Brown, V Di Cerbo, A Feldmann, J Ahn, S Ito, NP Blackledge, ...
Cell reports 20 (10), 2313-2327, 2017
MLL-AF4 spreading identifies binding sites that are distinct from super-enhancers and that govern sensitivity to DOT1L inhibition in leukemia
J Kerry, L Godfrey, E Repapi, M Tapia, NP Blackledge, H Ma, E Ballabio, ...
Cell reports 18 (2), 482-495, 2017
A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter
CJ Ott, M Suszko, NP Blackledge, JE Wright, GE Crawford, A Harris
Journal of cellular and molecular medicine 13 (4), 680-692, 2009
An insulator element 3′ to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells
NP Blackledge, CJ Ott, AE Gillen, A Harris
Nucleic acids research 37 (4), 1086-1094, 2009
Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes
HW King, NA Fursova, NP Blackledge, RJ Klose
Genome research 28 (10), 1494-1507, 2018
Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes.
HW King, NA Fursova, NP Blackledge, RJ Klose
bioRxiv, 280305, 2018
CTCF mediates insulator function at the CFTR locus
NP Blackledge, EJ Carter, JR Evans, V Lawson, RK Rowntree, A Harris
Biochemical Journal 408 (2), 267-275, 2007
CpG island chromatin is shaped by recruitment of ZF-CxxC proteins
NP Blackledge, JP Thomson, PJ Skene
Cold Spring Harbor perspectives in biology 5 (11), a018648, 2013
Recognition of CpG island chromatin by KDM2A requires direct and specific interaction with linker DNA
JC Zhou, NP Blackledge, AM Farcas, RJ Klose
Molecular and cellular biology 32 (2), 479-489, 2012
The system can't perform the operation now. Try again later.
Articles 1–20