The codependence of angiogenesis and chronic inflammation JR Jackson, MP Seed, CH Kircher, DA Willoughby, JD Winkler The FASEB journal 11 (6), 457-465, 1997 | 880 | 1997 |
An immune-active tumor microenvironment favors clinical response to ipilimumab RR Ji, SD Chasalow, L Wang, O Hamid, H Schmidt, J Cogswell, ... Cancer Immunology, Immunotherapy 61, 1019-1031, 2012 | 841 | 2012 |
Targeted anti-mitotic therapies: can we improve on tubulin agents? JR Jackson, DR Patrick, MM Dar, PS Huang Nature Reviews Cancer 7 (2), 107-117, 2007 | 624 | 2007 |
Discovery of GSK2126458, a highly potent inhibitor of PI3K and the mammalian target of rapamycin SD Knight, ND Adams, JL Burgess, AM Chaudhari, MG Darcy, ... ACS Medicinal Chemistry Letters 1 (1), 39-43, 2010 | 404 | 2010 |
Past and future of the mitotic spindle as an oncology target KW Wood, WD Cornwell, JR Jackson Current opinion in pharmacology 1 (4), 370-377, 2001 | 354 | 2001 |
An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage JR Jackson, A Gilmartin, C Imburgia, JD Winkler, LA Marshall, A Roshak Cancer research 60 (3), 566-572, 2000 | 318 | 2000 |
Expression of vascular endothelial growth factor in synovial fibroblasts is induced by hypoxia and interleukin 1beta. JR Jackson, JA Minton, ML Ho, N Wei, JD Winkler The Journal of rheumatology 24 (7), 1253-1259, 1997 | 305 | 1997 |
The identification and characterization of the marine natural product scytonemin as a novel antiproliferative pharmacophore CS Stevenson, EA Capper, AK Roshak, B Marquez, C Eichman, ... Journal of Pharmacology and Experimental Therapeutics 303 (2), 858-866, 2002 | 268 | 2002 |
Pharmacological effects of SB 220025, a selective inhibitor of P38 mitogen-activated protein kinase, in angiogenesis and chronic inflammatory disease models JR Jackson, B Bolognese, L Hillegass, S Kassis, J Adams, DE Griswold, ... Journal of Pharmacology and Experimental Therapeutics 284 (2), 687-692, 1998 | 236 | 1998 |
Antitumor activity of an allosteric inhibitor of centromere-associated protein-E KW Wood, L Lad, L Luo, X Qian, SD Knight, N Nevins, K Brejc, D Sutton, ... Proceedings of the National Academy of Sciences 107 (13), 5839-5844, 2010 | 229 | 2010 |
Manipulation of distinct NFκB proteins alters interleukin-1β-induced human rheumatoid synovial fibroblast prostaglandin E2 formation AK Roshak, JR Jackson, K McGough, M Chabot-Fletcher, E Mochan, ... Journal of Biological Chemistry 271 (49), 31496-31501, 1996 | 224 | 1996 |
In vitro antibody maturation. Improvement of a high affinity, neutralizing antibody against IL-1 beta. JR Jackson, G Sathe, M Rosenberg, R Sweet Journal of immunology (Baltimore, Md.: 1950) 154 (7), 3310-3319, 1995 | 213 | 1995 |
Alternative DNA-protein interactions in variable-length internucleosomal regions associated with Drosophila Adh distal promoter expression A Ewel, JR Jackson, C Benyajati Nucleic acids research 18 (7), 1771-1781, 1990 | 206 | 1990 |
Distinct concentration-dependent effects of the polo-like kinase 1–specific inhibitor GSK461364A, including differential effect on apoptosis AG Gilmartin, MR Bleam, MC Richter, SG Erskine, RG Kruger, L Madden, ... Cancer research 69 (17), 6969-6977, 2009 | 136 | 2009 |
Role of neutrophils in the deposition of platelets during acute inflammation. AC Issekutz, M Ripley, JR Jackson Laboratory Investigation; a Journal of Technical Methods and Pathology 49 (6 …, 1983 | 133 | 1983 |
ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanism L Luo, CA Parrish, N Nevins, DE McNulty, AM Chaudhari, JD Carson, ... Nature chemical biology 3 (11), 722-726, 2007 | 127 | 2007 |
Constitutive expression of angiopoietin-1 and-2 and modulation of their expression by inflammatory cytokines in rheumatoid arthritis synovial fibroblasts. BB Scott, PF Zaratin, A Colombo, MJ Hansbury, JD Winkler, JR Jackson The Journal of Rheumatology 29 (2), 230-239, 2002 | 113 | 2002 |
Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability Y Degenhardt, J Greshock, S Laquerre, AG Gilmartin, J Jing, M Richter, ... Molecular cancer therapeutics 9 (7), 2079-2089, 2010 | 103 | 2010 |
Novel ATP-competitive kinesin spindle protein inhibitors CA Parrish, ND Adams, KR Auger, JL Burgess, JD Carson, AM Chaudhari, ... Journal of Medicinal Chemistry 50 (20), 4939-4952, 2007 | 103 | 2007 |
Assessment of association between BRAF-V600E mutation status in melanomas and clinical response to ipilimumab V Shahabi, G Whitney, O Hamid, H Schmidt, SD Chasalow, S Alaparthy, ... Cancer Immunology, Immunotherapy 61, 733-737, 2012 | 96 | 2012 |