Rickie Patani
Rickie Patani
Professor, MRC Senior Clinical Fellow & Consultant Neurologist @ The Francis Crick Institute & UCL
Verified email at - Homepage
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Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
JR Tollervey, T Curk, B Rogelj, M Briese, M Cereda, M Kayikci, J K÷nig, ...
Nature neuroscience 14 (4), 452-458, 2011
Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study
P Connick, M Kolappan, C Crawley, DJ Webber, R Patani, AW Michell, ...
The Lancet Neurology 11 (2), 150-156, 2012
Remyelination can be extensive in multiple sclerosis despite a long disease course
R Patani, M Balaratnam, A Vora, R Reynolds
Neuropathology and applied neurobiology 33 (3), 277-287, 2007
Major shifts in glial regional identity are a transcriptional hallmark of human brain aging
L Soreq, J Rose, E Soreq, J Hardy, D Trabzuni, MR Cookson, C Smith, ...
Cell reports 18 (2), 557-570, 2017
A liquid to solid phase transition underlying pathological huntingtin exon1 aggregation
TR Peskett, F Rau, J O’Driscoll, R Patani, AR Lowe, HR Saibil
Molecular cell 70 (4), 588-601. e6, 2018
Three-dimensional human iPSC-derived artificial skeletal muscles model muscular dystrophies and enable multilineage tissue engineering
SM Maffioletti, S Sarcar, ABH Henderson, I Mannhardt, L Pinton, LA Moyle, ...
Cell Reports 23 (3), 899-908, 2018
G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology inávitro and inávivo
R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ...
EMBO molecular medicine 10 (1), 22-31, 2018
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS
CE Hall, Z Yao, M Choi, GE Tyzack, A Serio, R Luisier, J Harley, E Preza, ...
Cell reports 19 (9), 1739-1749, 2017
Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling
CL Tan, JCF Kwok, R Patani, S Chandran, JW Fawcett
Journal of Neuroscience 31 (17), 6289-6295, 2011
The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcomeá…
P Connick, M Kolappan, R Patani, MA Scott, C Crawley, XL He, ...
Trials 12, 1-10, 2011
Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning
KF Bell, B Al-Mubarak, JH Fowler, PS Baxter, K Gupta, T Tsujita, ...
Proceedings of the National Academy of Sciences 108 (1), E1-E2, 2011
Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis
GE Tyzack, R Luisier, DM Taha, J Neeves, M Modic, JS Mitchell, I Meyer, ...
Brain 142 (9), 2572-2580, 2019
In vitro prion-like behaviour of TDP-43 in ALS
P Smethurst, J Newcombe, C Troakes, R Simone, YR Chen, R Patani, ...
Neurobiology of disease 96, 236-247, 2016
Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis
JM Anderson, DW Hampton, R Patani, G Pryce, RA Crowther, R Reynolds, ...
Brain 131 (7), 1736-1748, 2008
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS
R Luisier, GE Tyzack, CE Hall, JS Mitchell, H Devine, DM Taha, B Malik, ...
Nature communications 9 (1), 2010, 2018
Dopamine from the brain promotes spinal motor neuron generation during development and adult regeneration
MM Reimer, A Norris, J Ohnmacht, R Patani, Z Zhong, TB Dias, V Kuscha, ...
Developmental cell 25 (5), 478-491, 2013
Cellular infiltration in traumatic brain injury
A Alam, EP Thelin, T Tajsic, DZ Khan, A Khellaf, R Patani, A Helmy
Journal of neuroinflammation 17, 1-17, 2020
TDP-43 condensation properties specify its RNA-binding and regulatory repertoire
M Hallegger, AM Chakrabarti, FCY Lee, BL Lee, AG Amalietti, HM Odeh, ...
Cell 184 (18), 4680-4696. e22, 2021
Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity
R Patani, A Compston, CA Puddifoot, DJA Wyllie, GE Hardingham, ...
PloS one 4 (10), e7327, 2009
Kir4. 1-dependent astrocyte-fast motor neuron interactions are required for peak strength
KW Kelley, LB Haim, L Schirmer, GE Tyzack, M Tolman, JG Miller, ...
Neuron 98 (2), 306-319. e7, 2018
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