Characterizing the RNA targets and position-dependent splicing regulation by TDP-43 JR Tollervey, T Curk, B Rogelj, M Briese, M Cereda, M Kayikci, J König, ... Nature neuroscience 14 (4), 452-458, 2011 | 1273 | 2011 |
Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study P Connick, M Kolappan, C Crawley, DJ Webber, R Patani, AW Michell, ... The Lancet Neurology 11 (2), 150-156, 2012 | 752 | 2012 |
Major shifts in glial regional identity are a transcriptional hallmark of human brain aging L Soreq, J Rose, E Soreq, J Hardy, D Trabzuni, MR Cookson, C Smith, ... Cell reports 18 (2), 557-570, 2017 | 398 | 2017 |
Remyelination can be extensive in multiple sclerosis despite a long disease course R Patani, M Balaratnam, A Vora, R Reynolds Neuropathology and applied neurobiology 33 (3), 277-287, 2007 | 376 | 2007 |
A liquid to solid phase transition underlying pathological huntingtin exon1 aggregation TR Peskett, F Rau, J O’Driscoll, R Patani, AR Lowe, HR Saibil Molecular cell 70 (4), 588-601. e6, 2018 | 322 | 2018 |
Three-dimensional human iPSC-derived artificial skeletal muscles model muscular dystrophies and enable multilineage tissue engineering SM Maffioletti, S Sarcar, ABH Henderson, I Mannhardt, L Pinton, LA Moyle, ... Cell Reports 23 (3), 899-908, 2018 | 289 | 2018 |
G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ... EMBO molecular medicine 10 (1), 22-31, 2018 | 217 | 2018 |
Cellular infiltration in traumatic brain injury A Alam, EP Thelin, T Tajsic, DZ Khan, A Khellaf, R Patani, A Helmy Journal of neuroinflammation 17, 1-17, 2020 | 201 | 2020 |
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS CE Hall, Z Yao, M Choi, GE Tyzack, A Serio, R Luisier, J Harley, E Preza, ... Cell reports 19 (9), 1739-1749, 2017 | 201 | 2017 |
Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration R Patani, GE Hardingham, SA Liddelow Nature Reviews Neurology 19 (7), 395-409, 2023 | 182 | 2023 |
Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis GE Tyzack, R Luisier, DM Taha, J Neeves, M Modic, JS Mitchell, I Meyer, ... Brain 142 (9), 2572-2580, 2019 | 172 | 2019 |
Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling CL Tan, JCF Kwok, R Patani, S Chandran, JW Fawcett Journal of Neuroscience 31 (17), 6289-6295, 2011 | 168 | 2011 |
TDP-43 condensation properties specify its RNA-binding and regulatory repertoire M Hallegger, AM Chakrabarti, FCY Lee, BL Lee, AG Amalietti, HM Odeh, ... Cell 184 (18), 4680-4696. e22, 2021 | 166 | 2021 |
Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning KF Bell, B Al-Mubarak, JH Fowler, PS Baxter, K Gupta, T Tsujita, ... Proceedings of the National Academy of Sciences 108 (1), E1-E2, 2011 | 162 | 2011 |
The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome … P Connick, M Kolappan, R Patani, MA Scott, C Crawley, XL He, ... Trials 12, 1-10, 2011 | 159 | 2011 |
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS R Luisier, GE Tyzack, CE Hall, JS Mitchell, H Devine, DM Taha, B Malik, ... Nature communications 9 (1), 2010, 2018 | 158 | 2018 |
In vitro prion-like behaviour of TDP-43 in ALS P Smethurst, J Newcombe, C Troakes, R Simone, YR Chen, R Patani, ... Neurobiology of disease 96, 236-247, 2016 | 157 | 2016 |
Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis JM Anderson, DW Hampton, R Patani, G Pryce, RA Crowther, R Reynolds, ... Brain 131 (7), 1736-1748, 2008 | 154 | 2008 |
Dopamine from the brain promotes spinal motor neuron generation during development and adult regeneration MM Reimer, A Norris, J Ohnmacht, R Patani, Z Zhong, TB Dias, V Kuscha, ... Developmental cell 25 (5), 478-491, 2013 | 144 | 2013 |
Kir4. 1-dependent astrocyte-fast motor neuron interactions are required for peak strength KW Kelley, LB Haim, L Schirmer, GE Tyzack, M Tolman, JG Miller, ... Neuron 98 (2), 306-319. e7, 2018 | 122 | 2018 |