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Sebastian Lourido
Sebastian Lourido
Whitehead Institute for Biomedical Research
Verified email at wi.mit.edu - Homepage
Title
Cited by
Cited by
Year
A genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes
SM Sidik, D Huet, SM Ganesan, MH Huynh, T Wang, AS Nasamu, P Thiru, ...
Cell 166 (6), 1423-1435. e12, 2016
7852016
Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose
JS Chahal, OF Khan, CL Cooper, JS McPartlan, JK Tsosie, LD Tilley, ...
Proceedings of the National Academy of Sciences 113 (29), E4133-E4142, 2016
4412016
Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma
S Lourido, J Shuman, C Zhang, KM Shokat, R Hui, LD Sibley
Nature 465 (7296), 359-362, 2010
3762010
Calcium-dependent signaling and kinases in apicomplexan parasites
O Billker, S Lourido, LD Sibley
Cell host & microbe 5 (6), 612-622, 2009
3542009
How do microbes evade neutrophil killing?
CF Urban, S Lourido, A Zychlinsky
Cellular microbiology 8 (11), 1687-1696, 2006
3122006
Efficient genome engineering of Toxoplasma gondii using CRISPR/Cas9
SM Sidik, CG Hackett, F Tran, NJ Westwood, S Lourido
PloS one 9 (6), e100450, 2014
2832014
The Toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole
DA Gold, AD Kaplan, A Lis, GCL Bett, EE Rosowski, KM Cirelli, ...
Cell host & microbe 17 (5), 642-652, 2015
2562015
Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium
AK Wernimont, JD Artz, P Finerty Jr, YH Lin, M Amani, A Allali-Hassani, ...
Nature structural & molecular biology 17 (5), 596-601, 2010
2492010
Distinct signalling pathways control Toxoplasma egress and host‐cell invasion
S Lourido, K Tang, LD Sibley
The EMBO journal 31 (24), 4524-4534, 2012
2322012
Identification of a master regulator of differentiation in Toxoplasma
BS Waldman, D Schwarz, MH Wadsworth, JP Saeij, AK Shalek, S Lourido
Cell 180 (2), 359-372. e16, 2020
2162020
The calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium spp
S Lourido, SNJ Moreno
Cell calcium 57 (3), 186-193, 2015
1592015
Functional and computational genomics reveal unprecedented flexibility in stage-specific Toxoplasma metabolism
A Krishnan, J Kloehn, M Lunghi, A Chiappino-Pepe, BS Waldman, ...
Cell host & microbe 27 (2), 290-306. e11, 2020
982020
In vivo CRISPR screen identifies TgWIP as a Toxoplasma modulator of dendritic cell migration
LO Sangaré, EB Ólafsson, Y Wang, N Yang, L Julien, A Camejo, ...
Cell host & microbe 26 (4), 478-492. e8, 2019
882019
Serum albumin stimulates protein kinase G-dependent microneme secretion in Toxoplasma gondii
KM Brown, S Lourido, LD Sibley
Journal of Biological Chemistry 291 (18), 9554-9565, 2016
782016
Toxoplasma gondii
S Lourido
Trends in Parasitology 35 (11), 944-945, 2019
712019
Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii
S Lourido, C Zhang, MS Lopez, K Tang, J Barks, Q Wang, SA Wildman, ...
Journal of medicinal chemistry 56 (7), 3068-3077, 2013
712013
CRISPR-Cas9-based genome-wide screening of Toxoplasma gondii
SM Sidik, D Huet, S Lourido
Nature protocols 13 (2), 307-323, 2018
702018
Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages
Y Wang, LO Sangaré, TC Paredes-Santos, MA Hassan, S Krishnamurthy, ...
Nature communications 11 (1), 5258, 2020
692020
One-step enzymatic modification of the cell surface redirects cellular cytotoxicity and parasite tropism
LK Swee, S Lourido, GW Bell, JR Ingram, HL Ploegh
ACS chemical biology 10 (2), 460-465, 2015
642015
Using a genetically encoded sensor to identify inhibitors of Toxoplasma gondii Ca2+ signaling
SM Sidik, MAH Triana, AS Paul, M El Bakkouri, CG Hackett, F Tran, ...
Journal of Biological Chemistry 291 (18), 9566-9580, 2016
632016
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