A genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes SM Sidik, D Huet, SM Ganesan, MH Huynh, T Wang, AS Nasamu, P Thiru, ... Cell 166 (6), 1423-1435. e12, 2016 | 785 | 2016 |
Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose JS Chahal, OF Khan, CL Cooper, JS McPartlan, JK Tsosie, LD Tilley, ... Proceedings of the National Academy of Sciences 113 (29), E4133-E4142, 2016 | 441 | 2016 |
Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma S Lourido, J Shuman, C Zhang, KM Shokat, R Hui, LD Sibley Nature 465 (7296), 359-362, 2010 | 376 | 2010 |
Calcium-dependent signaling and kinases in apicomplexan parasites O Billker, S Lourido, LD Sibley Cell host & microbe 5 (6), 612-622, 2009 | 354 | 2009 |
How do microbes evade neutrophil killing? CF Urban, S Lourido, A Zychlinsky Cellular microbiology 8 (11), 1687-1696, 2006 | 312 | 2006 |
Efficient genome engineering of Toxoplasma gondii using CRISPR/Cas9 SM Sidik, CG Hackett, F Tran, NJ Westwood, S Lourido PloS one 9 (6), e100450, 2014 | 283 | 2014 |
The Toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole DA Gold, AD Kaplan, A Lis, GCL Bett, EE Rosowski, KM Cirelli, ... Cell host & microbe 17 (5), 642-652, 2015 | 256 | 2015 |
Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium AK Wernimont, JD Artz, P Finerty Jr, YH Lin, M Amani, A Allali-Hassani, ... Nature structural & molecular biology 17 (5), 596-601, 2010 | 249 | 2010 |
Distinct signalling pathways control Toxoplasma egress and host‐cell invasion S Lourido, K Tang, LD Sibley The EMBO journal 31 (24), 4524-4534, 2012 | 232 | 2012 |
Identification of a master regulator of differentiation in Toxoplasma BS Waldman, D Schwarz, MH Wadsworth, JP Saeij, AK Shalek, S Lourido Cell 180 (2), 359-372. e16, 2020 | 216 | 2020 |
The calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium spp S Lourido, SNJ Moreno Cell calcium 57 (3), 186-193, 2015 | 159 | 2015 |
Functional and computational genomics reveal unprecedented flexibility in stage-specific Toxoplasma metabolism A Krishnan, J Kloehn, M Lunghi, A Chiappino-Pepe, BS Waldman, ... Cell host & microbe 27 (2), 290-306. e11, 2020 | 98 | 2020 |
In vivo CRISPR screen identifies TgWIP as a Toxoplasma modulator of dendritic cell migration LO Sangaré, EB Ólafsson, Y Wang, N Yang, L Julien, A Camejo, ... Cell host & microbe 26 (4), 478-492. e8, 2019 | 88 | 2019 |
Serum albumin stimulates protein kinase G-dependent microneme secretion in Toxoplasma gondii KM Brown, S Lourido, LD Sibley Journal of Biological Chemistry 291 (18), 9554-9565, 2016 | 78 | 2016 |
Toxoplasma gondii S Lourido Trends in Parasitology 35 (11), 944-945, 2019 | 71 | 2019 |
Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii S Lourido, C Zhang, MS Lopez, K Tang, J Barks, Q Wang, SA Wildman, ... Journal of medicinal chemistry 56 (7), 3068-3077, 2013 | 71 | 2013 |
CRISPR-Cas9-based genome-wide screening of Toxoplasma gondii SM Sidik, D Huet, S Lourido Nature protocols 13 (2), 307-323, 2018 | 70 | 2018 |
Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages Y Wang, LO Sangaré, TC Paredes-Santos, MA Hassan, S Krishnamurthy, ... Nature communications 11 (1), 5258, 2020 | 69 | 2020 |
One-step enzymatic modification of the cell surface redirects cellular cytotoxicity and parasite tropism LK Swee, S Lourido, GW Bell, JR Ingram, HL Ploegh ACS chemical biology 10 (2), 460-465, 2015 | 64 | 2015 |
Using a genetically encoded sensor to identify inhibitors of Toxoplasma gondii Ca2+ signaling SM Sidik, MAH Triana, AS Paul, M El Bakkouri, CG Hackett, F Tran, ... Journal of Biological Chemistry 291 (18), 9566-9580, 2016 | 63 | 2016 |