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Simon Lambden
Simon Lambden
Dept of Medicine, University of Cambridge
Verified email at cam.ac.uk - Homepage
Title
Cited by
Cited by
Year
The SOFA score—development, utility and challenges of accurate assessment in clinical trials
S Lambden, PF Laterre, MM Levy, B Francois
Critical Care 23, 1-9, 2019
7232019
Definitions and pathophysiology of vasoplegic shock
S Lambden, BC Creagh-Brown, J Hunt, C Summers, LG Forni
Critical Care 22, 1-8, 2018
1842018
Observational Skill-based Clinical Assessment tool for Resuscitation (OSCAR): development and validation
S Walker, S Brett, A McKay, S Lambden, C Vincent, N Sevdalis
Resuscitation 82 (7), 835-844, 2011
1242011
Unannounced in situ simulations: integrating training and clinical practice
ST Walker, N Sevdalis, A McKay, S Lambden, S Gautama, R Aggarwal, ...
BMJ quality & safety 22 (6), 453-458, 2013
932013
Bench to bedside review: Therapeutic modulation of nitric oxide in sepsis—An update
S Lambden
Intensive Care Medicine Experimental 7 (1), 64, 2019
652019
Dimethylarginine dimethylaminohydrolase 2 regulates nitric oxide synthesis and hemodynamics and determines outcome in polymicrobial sepsis
S Lambden, P Kelly, B Ahmetaj-Shala, Z Wang, B Lee, M Nandi, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 35 (6), 1382-1392, 2015
502015
Pharmacological inhibition of DDAH1 improves survival, haemodynamics and organ function in experimental septic shock
Z Wang, S Lambden, V Taylor, E Sujkovic, M Nandi, J Tomlinson, ...
Biochemical Journal 460 (2), 309-316, 2014
452014
sTREM-1 is a specific biomarker of TREM-1 pathway activation
L Jolly, K Carrasco, M Salcedo-Magguilli, JJ Garaud, S Lambden, ...
Cellular & molecular immunology 18 (8), 2054-2056, 2021
372021
Bilateral objective tinnitus secondary to congenital middle-ear myoclonus
GD Howsam, A Sharma, SP Lambden, J Fitzgerald, PR Prinsley
The Journal of Laryngology & Otology 119 (6), 489-491, 2005
372005
NMDA receptor modulation of glutamate release in activated neutrophils
AG Del Arroyo, A Hadjihambi, J Sanchez, E Turovsky, V Kasymov, D Cain, ...
EBioMedicine 47, 457-469, 2019
232019
The Imperial Paediatric Emergency Training Toolkit (IPETT) for use in paediatric emergency training: development and evaluation of feasibility and validity
S Lambden, C DeMunter, A Dowson, M Cooper, S Gautama, N Sevdalis
Resuscitation 84 (6), 831-836, 2013
222013
Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19
AH de Nooijer, I Grondman, S Lambden, EJ Kooistra, NAF Janssen, ...
Bioscience Reports 41 (7), BSR20210940, 2021
212021
Challenges in the anesthetic and intensive care management of acute ischemic stroke
MA Kirkman, S Lambden, M Smith
Journal of neurosurgical anesthesiology 28 (3), 214-232, 2016
152016
Rationale and protocol for the efficacy, safety and tolerability of nangibotide in patients with septic shock (ASTONISH) phase IIb randomised controlled trial
B Francois, S Lambden, S Gibot, M Derive, A Olivier, V Cuvier, S Witte, ...
BMJ open 11 (7), e042921, 2021
132021
Hypoxia causes increased monocyte nitric oxide synthesis which is mediated by changes in dimethylarginine dimethylaminohydrolase 2 expression in animal and human models of …
S Lambden, D Martin, K Vanezis, B Lee, J Tomlinson, S Piper, O Boruc, ...
Nitric Oxide 58, 59-66, 2016
122016
2-Hydroxyglutarate Metabolism Is Altered in an in vivo Model of LPS Induced Endotoxemia
SF Fitzpatrick, S Lambden, D Macias, Z Puthucheary, S Pietsch, L Mendil, ...
Frontiers in Physiology 11, 147, 2020
112020
The use of computers for perioperative simulation in anesthesia, critical care, and pain medicine
S Lambden, B Martin
Anesthesiology Clinics 29 (3), 521-531, 2011
112011
Acute intravascular haemolysis associated with intravenous administration of meropenem in a sixty four year old man
SP Lambden, J Akeru, NA Barrett
Journal of Population Therapeutics and Clinical Pharmacology 17 (1), 2010
92010
Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a …
B François, S Lambden, T Fivez, S Gibot, M Derive, JM Grouin, ...
The Lancet Respiratory Medicine 11 (10), 894-904, 2023
82023
Inhibition of dimethylarginine dimethylaminohydrolase 1 improves the outcome of sepsis in pregnant mice
J Zölner, S Lambden, NM Nasri, MR Johnson, J Leiper
Shock 54 (4), 498-506, 2020
82020
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Articles 1–20