Adrian Biddle
Adrian Biddle
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Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative
A Biddle, X Liang, L Gammon, B Fazil, LJ Harper, H Emich, DE Costea, ...
Cancer research 71 (15), 5317-5326, 2011
Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas
MK Jolly, JA Somarelli, M Sheth, A Biddle, SC Tripathi, AJ Armstrong, ...
Pharmacology & therapeutics 194, 161-184, 2019
Cancer stem cells and EMT in carcinoma
A Biddle, IC Mackenzie
Cancer and Metastasis Reviews 31, 285-293, 2012
Pre‐culturing human adipose tissue mesenchymal stem cells under hypoxia increases their adipogenic and osteogenic differentiation potentials
MG Valorani, E Montelatici, A Germani, A Biddle, D D'Alessandro, ...
Cell proliferation 45 (3), 225-238, 2012
Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance
LJ Harper, DE Costea, L Gammon, B Fazil, A Biddle, IC Mackenzie
BMC cancer 10, 1-16, 2010
Phenotypic plasticity determines cancer stem cell therapeutic resistance in oral squamous cell carcinoma
A Biddle, L Gammon, X Liang, DE Costea, IC Mackenzie
EBioMedicine 4, 138-145, 2016
Epidermal growth factor receptor tyrosine kinase inhibition represses cyclin D1 in aerodigestive tract cancers
WJ Petty, KH Dragnev, VA Memoli, Y Ma, NB Desai, A Biddle, TH Davis, ...
Clinical cancer research 10 (22), 7547-7554, 2004
Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism
L Gammon, A Biddle, HK Heywood, AC Johannessen, IC Mackenzie
PloS one 8 (4), e62493, 2013
CD44 staining of cancer stem-like cells is influenced by down-regulation of CD44 variant isoforms and up-regulation of the standard CD44 isoform in the population of cells that …
A Biddle, L Gammon, B Fazil, IC Mackenzie
PloS one 8 (2), e57314, 2013
Hypoxia increases Sca-1/CD44 co-expression in murine mesenchymal stem cells and enhances their adipogenic differentiation potential
MG Valorani, A Germani, WR Otto, L Harper, A Biddle, CP Khoo, WR Lin, ...
Cell and tissue research 341, 111-120, 2010
A novel retinoic acid receptor β isoform and retinoid resistance in lung carcinogenesis
WJ Petty, N Li, A Biddle, R Bounds, C Nitkin, Y Ma, KH Dragnev, ...
Journal of the National Cancer Institute 97 (22), 1645-1651, 2005
Maintenance of stem cell self-renewal in head and neck cancers requires actions of GSK3β influenced by CD44 and RHAMM
H Shigeishi, A Biddle, L Gammon, H Emich, CO Rodini, E Gemenetzidis, ...
Stem Cells 31 (10), 2073-2083, 2013
Expression of betapapillomavirus oncogenes increases the number of keratinocytes with stem cell-like properties
M Hufbauer, A Biddle, C Borgogna, M Gariglio, J Doorbar, A Storey, ...
Journal of virology 87 (22), 12158-12165, 2013
Bexarotene and erlotinib for aerodigestive tract cancer
KH Dragnev, WJ Petty, S Shah, A Biddle, NB Desai, V Memoli, JR Rigas, ...
Journal of clinical oncology 23 (34), 8757-8764, 2005
Reprogramming to developmental plasticity in cancer stem cells
C O’Brien-Ball, A Biddle
Developmental biology 430 (2), 266-274, 2017
Portrait of a CAF: The story of cancer-associated fibroblasts in head and neck cancer
M Custódio, A Biddle, M Tavassoli
Oral Oncology 110, 104972, 2020
Invasive oral cancer stem cells display resistance to ionising radiation
E Gemenetzidis, L Gammon, A Biddle, H Emich, IC Mackenzie
Oncotarget 6 (41), 43964, 2015
Effects of Cetuximab and Erlotinib on the behaviour of cancer stem cells in head and neck squamous cell carcinoma
MFSD Rodrigues, L Gammon, MM Rahman, A Biddle, FD Nunes, ...
Oncotarget 9 (17), 13488, 2018
Phenotypic plasticity and epithelial‐to‐mesenchymal transition in the behaviour and therapeutic response of oral squamous cell carcinoma
N Vig, IC Mackenzie, A Biddle
Journal of Oral Pathology & Medicine 44 (9), 649-655, 2015
Elevation in 5‐FU‐induced apoptosis in Head and Neck Cancer Stem Cells by a combination of CDHP and GSK 3β inhibitors
H Shigeishi, A Biddle, L Gammon, CO Rodini, M Yamasaki, S Seino, ...
Journal of Oral Pathology & Medicine 44 (3), 201-207, 2015
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