| Role of quinones in toxicology JL Bolton, MA Trush, TM Penning, G Dryhurst, TJ Monks Chemical research in toxicology 13 (3), 135-160, 2000 | 2032 | 2000 |
| Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer M Stanbrough, GJ Bubley, K Ross, TR Golub, MA Rubin, TM Penning, ... Cancer research 66 (5), 2815-2825, 2006 | 1363 | 2006 |
| Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease LE Tebay, H Robertson, ST Durant, SR Vitale, TM Penning, ... Free Radical Biology and Medicine 88, 108-146, 2015 | 854 | 2015 |
| Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1–AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the … TM Penning, ME Burczynski, JM Jez, CF Hung, HK Lin, H Ma, M Moore, ... Biochemical journal 351 (1), 67-77, 2000 | 785 | 2000 |
| Comparative anatomy of the aldo–keto reductase superfamily JM Jez, MJ Bennett, BP Schlegel, M Lewis, TM Penning Biochemical Journal 326 (3), 625-636, 1997 | 759 | 1997 |
| Molecular endocrinology of hydroxysteroid dehydrogenases TM Penning Endocrine reviews 18 (3), 281-305, 1997 | 597 | 1997 |
| Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: generation of reactive and redox active o-quinones TM Penning, ME Burczynski, CF Hung, KD McCoull, NT Palackal, ... Chemical research in toxicology 12 (1), 1-18, 1999 | 570 | 1999 |
| The biochemical basis for increased testosterone production in theca cells propagated from patients with polycystic ovary syndrome VL Nelson, K Qin, RL Rosenfield, JR Wood, TM Penning, RS Legro, ... The Journal of Clinical Endocrinology & Metabolism 86 (12), 5925-5933, 2001 | 547 | 2001 |
| The aldo-keto reductases (AKRs): Overview TM Penning Chemico-biological interactions 234, 236-246, 2015 | 489 | 2015 |
| A new nomenclature for the aldo-keto reductase superfamily JM Jez, TG Flynn, TM Penning Biochemical pharmacology 54 (6), 639-647, 1997 | 454 | 1997 |
| The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative B Persson, Y Kallberg, JE Bray, E Bruford, SL Dellaporta, AD Favia, ... Chemico-biological interactions 178 (1-3), 94-98, 2009 | 444 | 2009 |
| Aldo-keto reductases and bioactivation/detoxication Y Jin, TM Penning Annu. Rev. Pharmacol. Toxicol. 47 (1), 263-292, 2007 | 440 | 2007 |
| The aldo-keto reductase superfamily homepage D Hyndman, DR Bauman, VV Heredia, TM Penning Chemico-biological interactions 143, 621-631, 2003 | 383 | 2003 |
| Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1–NRF2 pathway, and not the BACH1–NRF2 pathway … AK MacLeod, M McMahon, SM Plummer, LG Higgins, TM Penning, ... Carcinogenesis 30 (9), 1571-1580, 2009 | 363 | 2009 |
| Clustering a chemical inventory for safety assessment of fragrance ingredients: identifying read-across analogs to address data gaps MS Date, D O’Brien, DJ Botelho, TW Schultz, DC Liebler, TM Penning, ... Chemical research in toxicology 33 (7), 1709-1718, 2020 | 360 | 2020 |
| Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer KE Knudsen, TM Penning Trends in Endocrinology & Metabolism 21 (5), 315-324, 2010 | 354 | 2010 |
| Human aldo–keto reductases: function, gene regulation, and single nucleotide polymorphisms TM Penning, JE Drury Archives of biochemistry and biophysics 464 (2), 241-250, 2007 | 332 | 2007 |
| Human cytosolic 3α-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3β-hydroxysteroid dehydrogenase activity: implications for steroid … S Steckelbroeck, Y Jin, S Gopishetty, B Oyesanmi, TM Penning Journal of biological chemistry 279 (11), 10784-10795, 2004 | 317 | 2004 |
| Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: a mechanistic approach to the design of COX-1 selective agents LM Szewczuk, L Forti, LA Stivala, TM Penning Journal of biological chemistry 279 (21), 22727-22737, 2004 | 315 | 2004 |
| The aldo-keto reductase (AKR) superfamily: an update JM Jez, TM Penning Chemico-biological interactions 130, 499-525, 2001 | 304 | 2001 |
