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colin macphee
colin macphee
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Year
Resistin is expressed in human macrophages and directly regulated by PPARγ activators
L Patel, AC Buckels, IJ Kinghorn, PR Murdock, JD Holbrook, C Plumpton, ...
Biochemical and biophysical research communications 300 (2), 472-476, 2003
13792003
Lipoprotein-Associated Phospholipase A2 as an Independent Predictor of Coronary Heart Disease
CJ Packard, DSJ O'Reilly, MJ Caslake, AD McMahon, I Ford, J Cooney, ...
New England Journal of Medicine 343 (16), 1148-1155, 2000
12022000
Role of Lipoprotein-Associated Phospholipase A2 in Atherosclerosis: Biology, Epidemiology, and Possible Therapeutic Target
A Zalewski, C Macphee
Arteriosclerosis, thrombosis, and vascular biology 25 (5), 923-931, 2005
7232005
Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo
SU Naik, X Wang, JS Da Silva, M Jaye, CH Macphee, MP Reilly, ...
Circulation 113 (1), 90-97, 2006
4882006
Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN
L Patel, I Pass, P Coxon, CP Downes, SA Smith, CH Macphee
Current Biology 11 (10), 764-768, 2001
4872001
Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a …
CH MACPHEE, KE MOORES, HF BOYD, D DHANAK, RJ IFE, CA LEACH, ...
Biochemical Journal 338 (2), 479-487, 1999
4651999
Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
RL Wilensky, YI Shi, ER Mohler III, D Hamamdzic, ME Burgert, J Li, ...
Nature medicine 14 (10), 1059-1066, 2008
4462008
Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase: a potential new risk factor for coronary artery disease
MJ Caslake, CJ Packard, KE Suckling, SD Holmes, P Chamberlain, ...
Atherosclerosis 150 (2), 413-419, 2000
4222000
Lipoprotein-Associated Phospholipase A2, Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions
T Häkkinen, JS Luoma, MO Hiltunen, CH Macphee, KJ Milliner, L Patel, ...
Arteriosclerosis, thrombosis, and vascular biology 19 (12), 2909-2917, 1999
3671999
The peroxisome proliferator-activated receptor δ promotes lipid accumulation in human macrophages
H Vosper, L Patel, TL Graham, GA Khoudoli, A Hill, CH Macphee, I Pinto, ...
Journal of Biological Chemistry 276 (47), 44258-44265, 2001
3642001
myo‐Inositol metabolites as cellular signals
CP Downes, CH Macphee
European Journal of Biochemistry 193 (1), 1-18, 1990
2731990
Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins
DG Tew, C Southan, SQJ Rice, GMP Lawrence, H Li, HF Boyd, K Moores, ...
Arteriosclerosis, thrombosis, and vascular biology 16 (4), 591-599, 1996
2301996
Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils
JR White, C Imburgia, E Dul, E Appelbaum, K O'Donnell, DJ O'Shannessy, ...
Journal of leukocyte biology 62 (5), 667-675, 1997
2101997
Role of lipoprotein-associated phospholipase A2 in leukocyte activation and inflammatory responses
Y Shi, P Zhang, LF Zhang, H Osman, ER Mohler III, C Macphee, ...
Atherosclerosis 191 (1), 54-62, 2007
2032007
Phosphorylation results in activation of a cAMP phosphodiesterase in human platelets.
CH Macphee, DH Reifsnyder, TA Moore, KM Lerea, JA Beavo
Journal of Biological Chemistry 263 (21), 10353-10358, 1988
1851988
Lipoprotein-associated phospholipase A2 and atherosclerosis
RL Wilensky, CH Macphee
Current opinion in lipidology 20 (5), 415-420, 2009
1642009
Inhibition of lipoprotein-associated phospholipase A2 diminishes the death-inducing effects of oxidised LDL on human monocyte-macrophages
KLH Carpenter, IF Dennis, IR Challis, DP Osborn, CH Macphee, ...
FEBS letters 505 (3), 357-363, 2001
1622001
The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A2
JA Blackie, JC Bloomer, MJB Brown, HY Cheng, B Hammond, ...
Bioorganic & medicinal chemistry letters 13 (6), 1067-1070, 2003
1582003
Diabetes and hypercholesterolemia increase blood-brain barrier permeability and brain amyloid deposition: beneficial effects of the LpPLA2 inhibitor darapladib
NK Acharya, EC Levin, PM Clifford, M Han, R Tourtellotte, D Chamberlain, ...
Journal of Alzheimer's Disease 35 (1), 179-198, 2013
1542013
Lipoprotein-associated phospholipase A2: a potential new risk factor for coronary artery disease and a therapeutic target
CH Macphee
Current opinion in pharmacology 1 (2), 121-125, 2001
1502001
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