David Rubinsztein
David Rubinsztein
Verified email at hermes.cam.ac.uk - Homepage
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
9947*2021
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ...
Nature genetics 45 (12), 1452-1458, 2013
30422013
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ...
Nature genetics 41 (10), 1088-1093, 2009
27362009
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
L Galluzzi, I Vitale, JM Abrams, ES Alnemri, EH Baehrecke, ...
Cell Death & Differentiation 19 (1), 107-120, 2012
26072012
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar, C Vacher, Z Berger, JE Davies, S Luo, LG Oroz, F Scaravilli, ...
Nature genetics 36 (6), 585-595, 2004
24542004
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
20382018
TFEB links autophagy to lysosomal biogenesis
C Settembre, C Di Malta, VA Polito, MG Arencibia, F Vetrini, S Erdin, ...
science 332 (6036), 1429-1433, 2011
20312011
Autophagy and aging
DC Rubinsztein, G Mariņo, G Kroemer
Cell 146 (5), 682-695, 2011
18572011
The roles of intracellular protein-degradation pathways in neurodegeneration
DC Rubinsztein
Nature 443 (7113), 780-786, 2006
17982006
Regulation of mammalian autophagy in physiology and pathophysiology
B Ravikumar, S Sarkar, JE Davies, M Futter, M Garcia-Arencibia, ...
Physiological reviews 90 (4), 1383-1435, 2010
17262010
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ...
Nature genetics 43 (5), 429-435, 2011
17142011
α-Synuclein is degraded by both autophagy and the proteasome
JL Webb, B Ravikumar, J Atkins, JN Skepper, DC Rubinsztein
Journal of Biological Chemistry 278 (27), 25009-25013, 2003
14412003
Autophagy modulation as a potential therapeutic target for diverse diseases
DC Rubinsztein, P Codogno, B Levine
Nature reviews Drug discovery 11 (9), 709-730, 2012
12952012
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
B Ravikumar, R Duden, DC Rubinsztein
Human molecular genetics 11 (9), 1107-1117, 2002
11832002
Potential therapeutic applications of autophagy
DC Rubinsztein, JE Gestwicki, LO Murphy, DJ Klionsky
Nature reviews Drug discovery 6 (4), 304-312, 2007
11452007
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein
S Sarkar, JE Davies, Z Huang, A Tunnacliffe, DC Rubinsztein
Journal of Biological Chemistry 282 (8), 5641-5652, 2007
10292007
Lithium induces autophagy by inhibiting inositol monophosphatase
S Sarkar, RA Floto, Z Berger, S Imarisio, A Cordenier, M Pasco, LJ Cook, ...
Journal of Cell Biology 170 (7), 1101-1111, 2005
9842005
Analysis of shared heritability in common disorders of the brain
V Anttila, B Bulik-Sullivan, HK Finucane, RK Walters, J Bras, L Duncan, ...
Science 360 (6395), 2018
9782018
Plasma membrane contributes to the formation of pre-autophagosomal structures
B Ravikumar, K Moreau, L Jahreiss, C Puri, DC Rubinsztein
Nature cell biology 12 (8), 747-757, 2010
9342010
Autophagy in malignant transformation and cancer progression
L Galluzzi, F Pietrocola, JM Bravo‐San Pedro, RK Amaravadi, ...
The EMBO journal 34 (7), 856-880, 2015
9072015
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Articles 1–20