Erik Sahai
TitleCited byYear
RHO–GTPases and cancer
E Sahai, CJ Marshall
Nature Reviews Cancer 2 (2), 133, 2002
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
ML Coleman, EA Sahai, M Yeo, M Bosch, A Dewar, MF Olson
Nature cell biology 3 (4), 339, 2001
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
E Sahai, CJ Marshall
Nature cell biology 5 (8), 711, 2003
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
C Gaggioli, S Hooper, C Hidalgo-Carcedo, R Grosse, JF Marshall, ...
Nature cell biology 9 (12), 1392, 2007
Rac activation and inactivation control plasticity of tumor cell movement
V Sanz-Moreno, G Gadea, J Ahn, H Paterson, P Marra, S Pinner, E Sahai, ...
Cell 135 (3), 510-523, 2008
Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop
S Goswami, E Sahai, JB Wyckoff, M Cammer, D Cox, FJ Pixley, ...
Cancer research 65 (12), 5278-5283, 2005
Classifying collective cancer cell invasion
P Friedl, J Locker, E Sahai, JE Segall
Nature cell biology 14 (8), 777, 2012
Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility
S Giampieri, C Manning, S Hooper, L Jones, CS Hill, E Sahai
Nature cell biology 11 (11), 1287, 2009
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
F Calvo, N Ege, A Grande-Garcia, S Hooper, RP Jenkins, SI Chaudhry, ...
Nature cell biology 15 (6), 637, 2013
Illuminating the metastatic process
E Sahai
Nature reviews cancer 7 (10), 737, 2007
Mechanisms of cancer cell invasion
E Sahai
Current opinion in genetics & development 15 (1), 87-96, 2005
ROCK and Dia have opposing effects on adherens junctions downstream of Rho
E Sahai, CJ Marshall
Nature cell biology 4 (6), 408, 2002
Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors
W Wang, S Goswami, K Lapidus, AL Wells, JB Wyckoff, E Sahai, ...
Cancer research 64 (23), 8585-8594, 2004
The actin cytoskeleton in cancer cell motility
MF Olson, E Sahai
Clinical & experimental metastasis 26 (4), 273, 2009
Cross‐talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility
E Sahai, MF Olson, CJ Marshall
The EMBO journal 20 (4), 755-766, 2001
ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility
E Vial, E Sahai, CJ Marshall
Cancer cell 4 (1), 67-79, 2003
ROCK-and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo
JB Wyckoff, SE Pinner, S Gschmeissner, JS Condeelis, E Sahai
Current Biology 16 (15), 1515-1523, 2006
Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling
T Tominaga, E Sahai, P Chardin, F McCormick, SA Courtneidge, ...
Molecular cell 5 (1), 13-25, 2000
Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs
C Swanton, M Marani, O Pardo, PH Warne, G Kelly, E Sahai, F Elustondo, ...
Cancer cell 11 (6), 498-512, 2007
Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis
S Medjkane, C Perez-Sanchez, C Gaggioli, E Sahai, R Treisman
Nature cell biology 11 (3), 257, 2009
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