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Erik Sahai
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RHO–GTPases and cancer
E Sahai, CJ Marshall
Nature Reviews Cancer 2 (2), 133-142, 2002
18852002
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
C Gaggioli, S Hooper, C Hidalgo-Carcedo, R Grosse, JF Marshall, ...
Nature cell biology 9 (12), 1392-1400, 2007
14932007
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
ML Coleman, EA Sahai, M Yeo, M Bosch, A Dewar, MF Olson
Nature cell biology 3 (4), 339-345, 2001
14502001
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
E Sahai, CJ Marshall
Nature cell biology 5 (8), 711-719, 2003
13512003
A framework for advancing our understanding of cancer-associated fibroblasts
E Sahai, I Astsaturov, E Cukierman, DG DeNardo, M Egeblad, RM Evans, ...
Nature Reviews Cancer 20 (3), 174-186, 2020
10342020
Rac activation and inactivation control plasticity of tumor cell movement
V Sanz-Moreno, G Gadea, J Ahn, H Paterson, P Marra, S Pinner, E Sahai, ...
Cell 135 (3), 510-523, 2008
10282008
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
F Calvo, N Ege, A Grande-Garcia, S Hooper, RP Jenkins, SI Chaudhry, ...
Nature cell biology 15 (6), 637-646, 2013
10192013
Classifying collective cancer cell invasion
P Friedl, J Locker, E Sahai, JE Segall
Nature cell biology 14 (8), 777-783, 2012
9362012
NK cells stimulate recruitment of cDC1 into the tumor microenvironment promoting cancer immune control
JP Böttcher, E Bonavita, P Chakravarty, H Blees, M Cabeza-Cabrerizo, ...
Cell 172 (5), 1022-1037. e14, 2018
8432018
Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop
S Goswami, E Sahai, JB Wyckoff, M Cammer, D Cox, FJ Pixley, ...
Cancer research 65 (12), 5278-5283, 2005
8402005
Cyclooxygenase-dependent tumor growth through evasion of immunity
S Zelenay, AG Van Der Veen, JP Böttcher, KJ Snelgrove, N Rogers, ...
Cell 162 (6), 1257-1270, 2015
7452015
Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility
S Giampieri, C Manning, S Hooper, L Jones, CS Hill, E Sahai
Nature cell biology 11 (11), 1287-1296, 2009
7052009
Illuminating the metastatic process
E Sahai
Nature Reviews Cancer 7 (10), 737-749, 2007
6832007
Mechanisms of cancer cell invasion
E Sahai
Current opinion in genetics & development 15 (1), 87-96, 2005
6502005
The actin cytoskeleton in cancer cell motility
MF Olson, E Sahai
Clinical & experimental metastasis 26 (4), 273-287, 2009
6042009
Physical influences of the extracellular environment on cell migration
G Charras, E Sahai
Nature reviews Molecular cell biology 15 (12), 813-824, 2014
5692014
ROCK and Dia have opposing effects on adherens junctions downstream of Rho
E Sahai, CJ Marshall
Nature cell biology 4 (6), 408-415, 2002
5662002
Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors
W Wang, S Goswami, K Lapidus, AL Wells, JB Wyckoff, E Sahai, ...
Cancer research 64 (23), 8585-8594, 2004
5472004
A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion
A Labernadie, T Kato, A Brugués, X Serra-Picamal, S Derzsi, E Arwert, ...
Nature cell biology 19 (3), 224-237, 2017
4932017
Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling
E Hirata, MR Girotti, A Viros, S Hooper, B Spencer-Dene, M Matsuda, ...
Cancer cell 27 (4), 574-588, 2015
4922015
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