Mehdi Bouhaddou
Mehdi Bouhaddou
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583 (7816), 459-468, 2020
The global phosphorylation landscape of SARS-CoV-2 infection
M Bouhaddou, D Memon, B Meyer, KM White, VV Rezelj, MC Marrero, ...
Cell 182 (3), 685-712. e19, 2020
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), 2020
Genetic screens identify host factors for SARS-CoV-2 and common cold coronaviruses
R Wang, CR Simoneau, J Kulsuptrakul, M Bouhaddou, KA Travisano, ...
Cell 184 (1), 106-119. e14, 2021
Drug response consistency in CCLE and CGP
M Bouhaddou, MS DiStefano, EA Riesel, E Carrasco, HY Holzapfel, ...
Nature 540 (7631), E9-E10, 2016
Engineered mammalian RNAi can elicit antiviral protection that negates the requirement for the interferon response
AA Benitez, LA Spanko, M Bouhaddou, D Sachs, B Robert tenOever
Cell reports 13 (7), 1456-1466, 2015
A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens
M Bouhaddou, AM Barrette, AD Stern, RJ Koch, MS DiStefano, EA Riesel, ...
PLoS computational biology 14 (3), e1005985, 2018
A comparison of mRNA sequencing with random primed and 3′-directed libraries
Y Xiong, M Soumillon, J Wu, J Hansen, B Hu, JG Van Hasselt, ...
Scientific reports 7 (1), 1-12, 2017
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A
KM White, R Rosales, S Yildiz, T Kehrer, L Miorin, E Moreno, S Jangra, ...
Science 371 (6532), 926-931, 2021
A SARS-CoV-2-human protein-protein interaction map reveals drug targets and potential drug-repurposing. bioRxiv
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, MJ O’Meara, ...
Preprint posted March 22, 2020
Dimerization-based control of cooperativity
M Bouhaddou, MR Birtwistle
Molecular bioSystems 10 (7), 1824-1832, 2014
The landscape of human cancer proteins targeted by SARS-CoV-2
B Tutuncuoglu, M Cakir, J Batra, M Bouhaddou, M Eckhardt, DE Gordon, ...
Cancer discovery 10 (7), 916-921, 2020
Integrating transcriptomic data with mechanistic systems pharmacology models for virtual drug combination trials
AM Barrette, M Bouhaddou, MR Birtwistle
ACS chemical neuroscience 9 (1), 118-129, 2018
Systems pharmacology and pharmacodynamics
V Sinha, SM Huang, DR Abernethy, Y Wang, P Zhao, I Zineh, ...
Springer International Publishing, 2016
Validating antibodies for quantitative western blot measurements with microwestern array
RJ Koch, AM Barrette, AD Stern, B Hu, M Bouhaddou, EU Azeloglu, ...
Scientific reports 8 (1), 1-10, 2018
Mapping the protein–protein and genetic interactions of cancer to guide precision medicine
M Bouhaddou, M Eckhardt, ZZC Naing, M Kim, T Ideker, NJ Krogan
Current opinion in genetics & development 54, 110-117, 2019
An integrated mechanistic model of pan-cancer driver pathways predicts stochastic proliferation and death
M Bouhaddou, AM Barrette, RJ Koch, MS DiStefano, EA Riesel, AD Stern, ...
BioRxiv, 128801, 2017
Analysis of copy number loss of the ErbB4 receptor tyrosine kinase in glioblastoma
DAC Jones, A Scanteianu, M DiStefano, M Bouhaddou, MR Birtwistle
Plos one 13 (1), e0190664, 2018
Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B. 1.1. 7 variant
AK Reuschl, LG Thorne, L Zuliani-Alvarez, M Bouhaddou, K Obernier, ...
bioRxiv, 2021
Fluorescence multiplexing with spectral imaging and combinatorics
HY Holzapfel, AD Stern, M Bouhaddou, CM Anglin, D Putur, S Comer, ...
ACS combinatorial science 20 (11), 653-659, 2018
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