Roberta Bianchi
Roberta Bianchi
Professore Associato di Farmacologia UniversitÓ degli Studi di Perugia
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Modulation of tryptophan catabolism by regulatory T cells
F Fallarino, U Grohmann, KW Hwang, C Orabona, C Vacca, R Bianchi, ...
Nature immunology 4 (12), 1206-1212, 2003
CTLA-4–Ig regulates tryptophan catabolism in vivo
U Grohmann, C Orabona, F Fallarino, C Vacca, F Calcinaro, A Falorni, ...
Nature immunology 3 (11), 1097-1101, 2002
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor ζ-chain and induce a regulatory phenotype in naive T cells
F Fallarino, U Grohmann, S You, BC McGrath, DR Cavener, C Vacca, ...
The Journal of Immunology 176 (11), 6752-6761, 2006
T cell apoptosis by tryptophan catabolism
F Fallarino, U Grohmann, C Vacca, R Bianchi, C Orabona, A Spreca, ...
Cell Death & Differentiation 9 (10), 1069-1077, 2002
Indoleamine 2, 3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
MT Pallotta, C Orabona, C Volpi, C Vacca, ML Belladonna, R Bianchi, ...
Nature immunology 12 (9), 870-878, 2011
Aryl hydrocarbon receptor control of a disease tolerance defence pathway
A Bessede, M Gargaro, MT Pallotta, D Matino, G Servillo, C Brunacci, ...
Nature 511 (7508), 184-190, 2014
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86
C Orabona, U Grohmann, ML Belladonna, F Fallarino, C Vacca, R Bianchi, ...
Nature immunology 5 (11), 1134-1142, 2004
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
U Grohmann, C Volpi, F Fallarino, S Bozza, R Bianchi, C Vacca, ...
Nature medicine 13 (5), 579-586, 2007
IL-12 acts directly on DC to promote nuclear localization of NF-κB and primes DC for IL-12 production
U Grohmann, ML Belladonna, R Bianchi, C Orabona, E Ayroldi, ...
Immunity 9 (3), 315-323, 1998
IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells
ML Belladonna, JC Renauld, R Bianchi, C Vacca, F Fallarino, C Orabona, ...
The Journal of Immunology 168 (11), 5448-5454, 2002
Functional expression of indoleamine 2, 3-dioxygenase by murine CD8α+ dendritic cells
F Fallarino, C Vacca, C Orabona, ML Belladonna, R Bianchi, B Marshall, ...
International Immunology 14 (1), 65-68, 2002
Murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to CD200 receptor engagement
F Fallarino, C Asselin-Paturel, C Vacca, R Bianchi, S Gizzi, MC Fioretti, ...
The Journal of Immunology 173 (6), 3748-3754, 2004
A relay pathway between arginine and tryptophan metabolism confers immunosuppressive properties on dendritic cells
G Mondanelli, R Bianchi, MT Pallotta, C Orabona, E Albini, A Iacono, ...
Immunity 46 (2), 233-244, 2017
S100B protein stimulates microglia migration via RAGE-dependent up-regulation of chemokine expression and release
R Bianchi, E Kastrisianaki, I Giambanco, R Donato
Journal of Biological Chemistry 286 (9), 7214-7226, 2011
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice
U Grohmann, F Fallarino, R Bianchi, C Orabona, C Vacca, MC Fioretti, ...
The Journal of experimental medicine 198 (1), 153-160, 2003
The pathophysiological role of microglia in dynamic surveillance, phagocytosis and structural remodeling of the developing CNS
C Arcuri, C Mecca, R Bianchi, I Giambanco, R Donato
Frontiers in molecular neuroscience 10, 191, 2017
IL-6 inhibits the tolerogenic function of CD8α+ dendritic cells expressing indoleamine 2, 3-dioxygenase
U Grohmann, F Fallarino, R Bianchi, ML Belladonna, C Vacca, C Orabona, ...
The Journal of Immunology 167 (2), 708-714, 2001
SOCS3 drives proteasomal degradation of indoleamine 2, 3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis
C Orabona, MT Pallotta, C Volpi, F Fallarino, C Vacca, R Bianchi, ...
Proceedings of the National Academy of Sciences 105 (52), 20828-20833, 2008
Toward the identification of a tolerogenic signature in IDO-competent dendritic cells
C Orabona, P Puccetti, C Vacca, S Bicciato, A Luchini, F Fallarino, ...
Blood 107 (7), 2846-2854, 2006
Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO
ML Belladonna, U Grohmann, P Guidetti, C Volpi, R Bianchi, MC Fioretti, ...
The Journal of Immunology 177 (1), 130-137, 2006
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