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Scott Guimond
Scott Guimond
Verified email at keele.ac.uk
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Year
Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor.
SH Kim, J Turnbull, S Guimond
The Journal of endocrinology 209 (2), 139-151, 2011
13822011
Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.
S Guimond, M Maccarana, BB Olwin, U Lindahl, AC Rapraeger
Journal of Biological Chemistry 268 (32), 23906-23914, 1993
7321993
Heparan sulfate: decoding a dynamic multifunctional cell regulator
J Turnbull, A Powell, S Guimond
Trends in cell biology 11 (2), 75-82, 2001
6002001
Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the spike S1 receptor-binding domain with heparin
CJ Mycroft-West, D Su, I Pagani, TR Rudd, S Elli, NS Gandhi, ...
Thrombosis and haemostasis 120 (12), 1700-1715, 2020
2942020
Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides
SE Guimond, JE Turnbull
Current Biology 9 (22), 1343-1346, 1999
2411999
The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding
C Mycroft-West, D Su, S Elli, Y Li, S Guimond, G Miller, J Turnbull, E Yates, ...
BioRxiv, 2020.02. 29.971093, 2020
2302020
Anosmin-1 modulates fibroblast growth factor receptor 1 signaling in human gonadotropin-releasing hormone olfactory neuroblasts through a heparan sulfate-dependent mechanism
D González-Martínez, SH Kim, Y Hu, S Guimond, J Schofield, P Winyard, ...
Journal of Neuroscience 24 (46), 10384-10392, 2004
1802004
[11] Regulation by heparan sulfate in fibroblast growth factor signaling
AC Rapraeger, S Guimond, A Krufka, BB Olwin
Methods in enzymology 245, 219-240, 1994
1441994
Localisation of specific heparan sulfate proteoglycans during the proliferative phase of brain development
M Ford‐Perriss, K Turner, S Guimond, A Apedaile, HD Haubeck, ...
Developmental dynamics: an official publication of the American Association …, 2003
1162003
Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1
Y Hu, SE Guimond, P Travers, S Cadman, E Hohenester, JE Turnbull, ...
Journal of Biological Chemistry 284 (43), 29905-29920, 2009
932009
Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling
M Ford-Perriss, SE Guimond, U Greferath, M Kita, K Grobe, H Habuchi, ...
Glycobiology 12 (11), 721-727, 2002
922002
Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity
R Xu, A Ori, TR Rudd, KA Uniewicz, YA Ahmed, SE Guimond, ...
Journal of Biological Chemistry 287 (47), 40061-40073, 2012
892012
Two hierarchies of FGF-2 signaling in heparin: mitogenic stimulation and high-affinity binding/receptor transphosphorylation
A Krufka, S Guimond, AC Rapraeger
Biochemistry 35 (34), 11131-11141, 1996
891996
Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives
TR Rudd, SE Guimond, MA Skidmore, L Duchesne, M Guerrini, G Torri, ...
Glycobiology 17 (9), 983-993, 2007
882007
Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction
SE Guimond, CJ Mycroft-West, NS Gandhi, JA Tree, TT Le, CM Spalluto, ...
ACS central science 8 (5), 527-545, 2022
732022
Disaccharide compositional analysis of heparan sulfate and heparin polysaccharides using UV or high-sensitivity fluorescence (BODIPY) detection
MA Skidmore, SE Guimond, AF Dumax-Vorzet, EA Yates, JE Turnbull
Nature protocols 5 (12), 1983-1992, 2010
722010
High sensitivity separation and detection of heparan sulfate disaccharides
MA Skidmore, SE Guimond, AF Dumax-Vorzet, A Atrih, EA Yates, ...
Journal of Chromatography A 1135 (1), 52-56, 2006
712006
Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra
TR Rudd, MA Skidmore, SE Guimond, C Cosentino, G Torri, DG Fernig, ...
Glycobiology 19 (1), 52-67, 2009
612009
Rapid Purification and High Sensitivity Analysis of Heparan Sulfate from Cells and Tissues: TOWARD GLYCOMICS PROFILING*♦
SE Guimond, TM Puvirajesinghe, MA Skidmore, I Kalus, T Dierks, ...
Journal of biological chemistry 284 (38), 25714-25722, 2009
582009
Highly diverse heparan sulfate analogue libraries: providing access to expanded areas of sequence space for bioactivity screening
EA Yates, SE Guimond, JE Turnbull
Journal of medicinal chemistry 47 (1), 277-280, 2004
552004
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