| The paradox of matrix metalloproteinases in infectious disease PTG Elkington, CM O'kane, JS Friedland Clinical & Experimental Immunology 142 (1), 12-20, 2005 | 427 | 2005 |
| Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment AK Coussens, RJ Wilkinson, Y Hanifa, V Nikolayevskyy, PT Elkington, ... Proceedings of the National Academy of Sciences 109 (38), 15449-15454, 2012 | 419 | 2012 |
| Matrix metalloproteinases in destructive pulmonary pathology PTG Elkington, JS Friedland Thorax 61 (3), 259-266, 2006 | 419 | 2006 |
| Optimisation of bioluminescent reporters for use with mycobacteria N Andreu, A Zelmer, T Fletcher, PT Elkington, TH Ward, J Ripoll, T Parish, ... PloS one 5 (5), e10777, 2010 | 346 | 2010 |
| MMP-1 drives immunopathology in human tuberculosis and transgenic mice P Elkington, T Shiomi, R Breen, RK Nuttall, CA Ugarte-Gil, NF Walker, ... The Journal of clinical investigation 121 (5), 1827-1833, 2011 | 289 | 2011 |
| Tuberculosis, pulmonary cavitation, and matrix metalloproteinases CWM Ong, PT Elkington, JS Friedland American journal of respiratory and critical care medicine 190 (1), 9-18, 2014 | 258 | 2014 |
| Neutrophil-derived MMP-8 drives AMPK-dependent matrix destruction in human pulmonary tuberculosis CWM Ong, PT Elkington, S Brilha, C Ugarte-Gil, MT Tome-Esteban, ... PLoS pathogens 11 (5), e1004917, 2015 | 227 | 2015 |
| Matrix metalloproteinases in tuberculosis PT Elkington, CA Ugarte-Gil, JS Friedland European respiratory journal 38 (2), 456-464, 2011 | 182 | 2011 |
| Hypoxia and tissue destruction in pulmonary TB M Belton, S Brilha, R Manavaki, F Mauri, K Nijran, YT Hong, NH Patel, ... Thorax 71 (12), 1145-1153, 2016 | 180 | 2016 |
| Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases NF Walker, SO Clark, T Oni, N Andreu, L Tezera, S Singh, L Saraiva, ... American journal of respiratory and critical care medicine 185 (9), 989-997, 2012 | 172 | 2012 |
| Mycobacterium tuberculosis up-regulates matrix metalloproteinase-1 secretion from human airway epithelial cells via a p38 MAPK switch PTG Elkington, JE Emerson, LDC Lopez-Pascua, CM O’Kane, ... The Journal of Immunology 175 (8), 5333-5340, 2005 | 144 | 2005 |
| Mycobacterium tuberculosis, but Not Vaccine BCG, Specifically Upregulates Matrix Metalloproteinase-1 PTG Elkington, RK Nuttall, JJ Boyle, CM O'Kane, DE Horncastle, ... American journal of respiratory and critical care medicine 172 (12), 1596-1604, 2005 | 138 | 2005 |
| Towards host-directed therapies for tuberculosis A Zumla, J Chakaya, M Hoelscher, F Ntoumi, R Rustomjee, C Vilaplana, ... Nature reviews Drug discovery 14 (8), 511-512, 2015 | 137 | 2015 |
| The extracellular matrix regulates granuloma necrosis in tuberculosis B Al Shammari, T Shiomi, L Tezera, MK Bielecka, V Workman, ... The Journal of infectious diseases 212 (3), 463-473, 2015 | 130 | 2015 |
| Mycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation A Kübler, B Luna, C Larsson, NC Ammerman, BB Andrade, M Orandle, ... The Journal of pathology 235 (3), 431-444, 2015 | 127 | 2015 |
| Tuberculosis immunopathology: the neglected role of extracellular matrix destruction PT Elkington, JM D’Armiento, JS Friedland Science translational medicine 3 (71), 71ps6-71ps6, 2011 | 121 | 2011 |
| Controlled generation of microspheres incorporating extracellular matrix fibrils for three‐dimensional cell culture VL Workman, LB Tezera, PT Elkington, SN Jayasinghe Advanced functional materials 24 (18), 2648-2657, 2014 | 119 | 2014 |
| Induced sputum MMP-1,-3 &-8 concentrations during treatment of tuberculosis CA Ugarte-Gil, P Elkington, RH Gilman, J Coronel, LB Tezera, ... PloS one 8 (4), e61333, 2013 | 116 | 2013 |
| Relationship between pulmonary matrix metalloproteinases and quantitative CT markers of small airways disease and emphysema in COPD K Ostridge, N Williams, V Kim, M Bennett, S Harden, L Welch, S Bourne, ... Thorax 71 (2), 126-132, 2016 | 110 | 2016 |
| Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α LB Tezera, MK Bielecka, P Ogongo, NF Walker, M Ellis, ... Elife 9, e52668, 2020 | 108 | 2020 |
