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Janine Kirstein
Janine Kirstein
Leibniz Institute on Aging
Verified email at leibniz-fli.de - Homepage
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Cited by
Cited by
Year
Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation
NB Nillegoda, J Kirstein, A Szlachcic, M Berynskyy, A Stank, F Stengel, ...
Nature 524 (7564), 247-251, 2015
3572015
Metazoan Hsp70 machines use Hsp110 to power protein disaggregation
H Rampelt, J Kirstein‐Miles, NB Nillegoda, K Chi, SR Scholz, RI Morimoto, ...
The EMBO journal 31 (21), 4221-4235, 2012
3392012
Adapting the machine: adaptor proteins for Hsp100/Clp and AAA+ proteases
J Kirstein, N Molière, DA Dougan, K Turgay
Nature Reviews Microbiology 7 (8), 589-599, 2009
2792009
The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease
J Kirstein, A Hoffmann, H Lilie, R Schmidt, H Rübsamen‐Waigmann, ...
EMBO molecular medicine 1 (1), 37-49, 2009
2422009
Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments
T Haslberger, A Zdanowicz, I Brand, J Kirstein, K Turgay, A Mogk, ...
Nature structural & molecular biology 15 (6), 641-650, 2008
1812008
Adaptor protein controlled oligomerization activates the AAA+ protein ClpC
J Kirstein, T Schlothauer, DA Dougan, H Lilie, G Tischendorf, A Mogk, ...
The EMBO journal 25 (7), 1481-1491, 2006
1692006
The nascent polypeptide‐associated complex is a key regulator of proteostasis
J Kirstein‐Miles, A Scior, E Deuerling, RI Morimoto
The EMBO journal 32 (10), 1451-1468, 2013
1682013
In-Depth Profiling of the LiaR Response of Bacillus subtilis
D Wolf, F Kalamorz, T Wecke, A Juszczak, U Mäder, G Homuth, ...
Journal of bacteriology 192 (18), 4680-4693, 2010
1412010
Function, evolution, and structure of J-domain proteins
HH Kampinga, C Andreasson, A Barducci, ME Cheetham, D Cyr, ...
Cell Stress and Chaperones 24, 7-15, 2019
1392019
A tyrosine kinase and its activator control the activity of the CtsR heat shock repressor in B. subtilis
J Kirstein, D Zühlke, U Gerth, K Turgay, M Hecker
The EMBO journal 24 (19), 3435-3445, 2005
1392005
Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex
A Scior, A Buntru, K Arnsburg, A Ast, M Iburg, K Juenemann, ML Pigazzini, ...
The EMBO journal 37 (2), 282-299, 2018
1222018
The tyrosine kinase McsB is a regulated adaptor protein for ClpCP
J Kirstein, DA Dougan, U Gerth, M Hecker, K Turgay
The EMBO Journal 26 (8), 2061-2070, 2007
1002007
Fine-Tuning in Regulation of Clp Protein Content in Bacillus subtilis
U Gerth, J Kirstein, J Mostertz, T Waldminghaus, M Miethke, H Kock, ...
Journal of bacteriology 186 (1), 179-191, 2004
942004
Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments
J Kirstein, D Morito, T Kakihana, M Sugihara, A Minnen, MS Hipp, ...
The EMBO Journal 34 (18), 2334-2349, 2015
882015
Reduced insulin/IGF-1 signaling restores the dynamic properties of key stress granule proteins during aging
MC Lechler, ED Crawford, N Groh, K Widmaier, R Jung, J Kirstein, ...
Cell reports 18 (2), 454-467, 2017
712017
Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains
C Haenig, N Atias, AK Taylor, A Mazza, MH Schaefer, J Russ, ...
Cell reports 32 (7), 2020
692020
A New Tyrosine Phosphorylation Mechanism Involved in Signal Transduction in Bacillus subtilis
J Kirstein, K Turgay
Journal of molecular microbiology and biotechnology 9 (3-4), 182-188, 2005
692005
Localization of general and regulatory proteolysis in Bacillus subtilis cells
J Kirstein, H Strahl, N Molière, LW Hamoen, K Turgay
Molecular microbiology 70 (3), 682-694, 2008
662008
In vivo properties of the disaggregase function of J‐proteins and Hsc70 in Caenorhabditis elegans stress and aging
J Kirstein, K Arnsburg, A Scior, A Szlachcic, DL Guilbride, RI Morimoto, ...
Aging cell 16 (6), 1414-1424, 2017
642017
mHTT seeding activity: a marker of disease progression and neurotoxicity in models of Huntington’s disease
A Ast, A Buntru, F Schindler, R Hasenkopf, A Schulz, L Brusendorf, ...
Molecular cell 71 (5), 675-688. e6, 2018
592018
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