Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging L Ritsma, SIJ Ellenbroek, A Zomer, HJ Snippert, FJ De Sauvage, ... Nature 507 (7492), 362-365, 2014 | 516 | 2014 |
Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases S Frentzas, E Simoneau, VL Bridgeman, PB Vermeulen, S Foo, ... Nature medicine 22 (11), 1294-1302, 2016 | 397 | 2016 |
Renal subcapsular transplantation of PSC-derived kidney organoids induces neo-vasculogenesis and significant glomerular and tubular maturation in vivo CW van den Berg, L Ritsma, MC Avramut, LE Wiersma, BM van den Berg, ... Stem cell reports 10 (3), 751-765, 2018 | 346 | 2018 |
Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen S Ariotti, JB Beltman, G Chodaczek, ME Hoekstra, AE Van Beek, ... Proceedings of the National Academy of Sciences 109 (48), 19739-19744, 2012 | 294 | 2012 |
Surgical implantation of an abdominal imaging window for intravital microscopy L Ritsma, EJA Steller, SIJ Ellenbroek, O Kranenburg, IHM Borel Rinkes, ... Nature protocols 8 (3), 583-594, 2013 | 253 | 2013 |
A versatile toolkit to produce sensitive FRET biosensors to visualize signaling in time and space RD Fritz, M Letzelter, A Reimann, K Martin, L Fusco, L Ritsma, B Ponsioen, ... Science signaling 6 (285), rs12-rs12, 2013 | 240 | 2013 |
Intravital microscopy through an abdominal imaging window reveals a pre-micrometastasis stage during liver metastasis L Ritsma, EJA Steller, E Beerling, CJM Loomans, A Zomer, C Gerlach, ... Science translational medicine 4 (158), 158ra145-158ra145, 2012 | 215 | 2012 |
Intravital microscopy: new insights into metastasis of tumors E Beerling, L Ritsma, N Vrisekoop, PWB Derksen, J van Rheenen Journal of cell science 124 (3), 299-310, 2011 | 168 | 2011 |
Imaging windows for long-term intravital imaging: General overview and technical insights M Alieva, L Ritsma, RJ Giedt, R Weissleder, J Van Rheenen Intravital 3 (2), e29917, 2014 | 165 | 2014 |
Brief report: Intravital imaging of cancer stem cell plasticity in mammary tumors A Zomer, SIJ Ellenbroek, L Ritsma, E Beerling, N Vrisekoop, ... Stem cells 31 (3), 602-606, 2013 | 157 | 2013 |
Direct spatial control of Epac1 by cyclic AMP B Ponsioen, M Gloerich, L Ritsma, H Rehmann, JL Bos, K Jalink Molecular and cellular biology, 2009 | 126 | 2009 |
Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins M Gloerich, B Ponsioen, MJ Vliem, Z Zhang, J Zhao, MR Kooistra, ... Molecular and cellular biology 30 (22), 5421-5431, 2010 | 76 | 2010 |
TGF-β family signaling pathways in cellular dormancy C Prunier, D Baker, P Ten Dijke, L Ritsma Trends in cancer 5 (1), 66-78, 2019 | 67 | 2019 |
The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion EJA Steller, L Ritsma, DAE Raats, FJH Hoogwater, BL Emmink, ... EMBO reports 12 (9), 931-937, 2011 | 59 | 2011 |
How the COVID-19 pandemic highlights the necessity of animal research L Genzel, R Adan, A Berns, JJJP van den Beucken, A Blokland, ... Current Biology 30 (18), R1014-R1018, 2020 | 54 | 2020 |
In vivo assessment of size-selective glomerular sieving in transplanted human induced pluripotent stem cell–derived kidney organoids CW Van Den Berg, A Koudijs, L Ritsma, TJ Rabelink Journal of the American Society of Nephrology 31 (5), 921-929, 2020 | 47 | 2020 |
PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena SK Hughes, MJ Oudin, J Tadros, J Neil, A Del Rosario, BA Joughin, ... Molecular biology of the cell 26 (21), 3867-3878, 2015 | 39 | 2015 |
In vivo imaging and histochemistry are combined in the cryosection labelling and intravital microscopy technique L Ritsma, N Vrisekoop, J Van Rheenen Nature communications 4 (1), 2366, 2013 | 38 | 2013 |
Intravital imaging of cell signaling in mice L Ritsma, B Ponsioen, J van Rheenen IntraVital 1 (1), 2-10, 2012 | 38 | 2012 |
Unbalancing the phosphatidylinositol-4, 5-bisphosphate–cofilin interaction impairs cell steering S Leyman, M Sidani, L Ritsma, D Waterschoot, R Eddy, D Dewitte, ... Molecular biology of the cell 20 (21), 4509-4523, 2009 | 35 | 2009 |