| Bone marrow stromal cell–derived exosomes as communicators in drug resistance in multiple myeloma cells J Wang, A Hendrix, S Hernot, M Lemaire, E De Bruyne, ... Blood, The Journal of the American Society of Hematology 124 (4), 555-566, 2014 | 440 | 2014 |
| Multiple myeloma exosomes establish a favourable bone marrow microenvironment with enhanced angiogenesis and immunosuppression J Wang, K De Veirman, S Faict, MA Frassanito, D Ribatti, A Vacca, ... The Journal of pathology 239 (2), 162-173, 2016 | 218 | 2016 |
| Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug J Hu, DR Handisides, E Van Valckenborgh, H De Raeve, E Menu, ... Blood, The Journal of the American Society of Hematology 116 (9), 1524-1527, 2010 | 168 | 2010 |
| A novel therapeutic combination using PD 0332991 and bortezomib: study in the 5T33MM myeloma model E Menu, J Garcia, X Huang, M Di Liberto, PL Toogood, I Chen, ... Cancer research 68 (14), 5519-5523, 2008 | 159 | 2008 |
| Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model E Menu, H Jernberg-Wiklund, T Stromberg, H De Raeve, L Girnita, ... Blood 107 (2), 655-660, 2006 | 158 | 2006 |
| The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells J Wang, K De Veirman, N De Beule, K Maes, E De Bruyne, ... Oncotarget 6 (41), 43992, 2015 | 155 | 2015 |
| Specific roles for the PI3K and the MEK–ERK pathway in IGF-1-stimulated chemotaxis, VEGF secretion and proliferation of multiple myeloma cells: study in the 5T33MM model E Menu, R Kooijman, E Van Valckenborgh, K Asosingh, M Bakkus, ... British journal of cancer 90 (5), 1076-1083, 2004 | 142 | 2004 |
| Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblasts S Faict, J Muller, K De Veirman, E De Bruyne, K Maes, L Vrancken, ... Blood cancer journal 8 (11), 105, 2018 | 134 | 2018 |
| Induction of miR-146a by multiple myeloma cells in mesenchymal stromal cells stimulates their pro-tumoral activity K De Veirman, J Wang, S Xu, X Leleu, E Himpe, K Maes, E De Bruyne, ... Cancer Letters 377 (1), 17-24, 2016 | 134 | 2016 |
| IGF-1 suppresses Bim expression in multiple myeloma via epigenetic and posttranslational mechanisms E De Bruyne, TJ Bos, F Schuit, E Van Valckenborgh, E Menu, L Thorrez, ... Blood, The Journal of the American Society of Hematology 115 (12), 2430-2440, 2010 | 129 | 2010 |
| Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model E Menu, E De Leenheer, H De Raeve, L Coulton, T Imanishi, K Miyashita, ... Clinical & experimental metastasis 23, 291-300, 2006 | 128 | 2006 |
| Myeloid-derived suppressor cells as therapeutic target in hematological malignancies K De Veirman, E Van Valckenborgh, Q Lahmar, X Geeraerts, E De Bruyne, ... Frontiers in oncology 4, 349, 2014 | 116 | 2014 |
| Bone marrow-derived mesenchymal stromal cells are attracted by multiple myeloma cell-produced chemokine CCL25 and favor myeloma cell growth in vitro and in vivo S Xu, E Menu, AD Becker, B Van Camp, K Vanderkerken, I Van Riet Stem Cells 30 (2), 266-279, 2012 | 116 | 2012 |
| Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies MA Frassanito, L Rao, M Moschetta, R Ria, L Di Marzo, A De Luisi, ... Leukemia 28 (4), 904-916, 2014 | 109 | 2014 |
| The involvement of stromal derived factor 1α in homing and progression of multiple myeloma in the 5TMM model E Menu, K Asosingh, S Indraccolo, H De Raeve, I Van Riet, ... Haematologica.-Roma 91 (5), 605-612, 2006 | 103 | 2006 |
| Activation of ATF4 mediates unwanted Mcl-1 accumulation by proteasome inhibition J Hu, N Dang, E Menu, E De Bryune, D Xu, B Van Camp, ... Blood, The Journal of the American Society of Hematology 119 (3), 826-837, 2012 | 97 | 2012 |
| Multiple myeloma induces the immunosuppressive capacity of distinct myeloid-derived suppressor cell subpopulations in the bone marrow E Van Valckenborgh, E Schouppe, K Movahedi, E De Bruyne, E Menu, ... Leukemia 26 (11), 2424-2428, 2012 | 95 | 2012 |
| Cancer associated fibroblasts and tumor growth: focus on multiple myeloma K De Veirman, L Rao, E De Bruyne, E Menu, E Van Valckenborgh, ... Cancers 6 (3), 1363-1381, 2014 | 89 | 2014 |
| Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma MA Economou, S Andersson, D Vasilcanu, C All-Ericsson, E Menu, ... Investigative ophthalmology & visual science 49 (6), 2337-2342, 2008 | 89 | 2008 |
| Novel strategies to target the ubiquitin proteasome system in multiple myeloma S Lub, K Maes, E Menu, E De Bruyne, K Vanderkerken, ... Oncotarget 7 (6), 6521, 2016 | 88 | 2016 |
