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Helen Dooley
Helen Dooley
University of Maryland School of Medicine
Verified email at som.umaryland.edu
Title
Cited by
Cited by
Year
Crystal structure of a shark single-domain antibody V region in complex with lysozyme
RL Stanfield, H Dooley, MF Flajnik, IA Wilson
Science 305 (5691), 1770-1773, 2004
3782004
Selection and characterization of naturally occurring single-domain (IgNAR) antibody fragments from immunized sharks by phage display
H Dooley, MF Flajnik, AJ Porter
Molecular immunology 40 (1), 25-33, 2003
2372003
Antibody repertoire development in cartilaginous fish
H Dooley, MF Flajnik
Developmental & Comparative Immunology 30 (1-2), 43-56, 2006
2282006
Shark immunity bites back: affinity maturation and memory response in the nurse shark, Ginglymostoma cirratum
H Dooley, MF Flajnik
European journal of immunology 35 (3), 936-945, 2005
1962005
Maturation of shark single-domain (IgNAR) antibodies: evidence for induced-fit binding
RL Stanfield, H Dooley, P Verdino, MF Flajnik, IA Wilson
Journal of molecular biology 367 (2), 358-372, 2007
1502007
First molecular and biochemical analysis of in vivo affinity maturation in an ectothermic vertebrate
H Dooley, RL Stanfield, RA Brady, MF Flajnik
Proceedings of the National Academy of Sciences 103 (6), 1846-1851, 2006
1322006
The immunoglobulins of cold-blooded vertebrates
R Pettinello, H Dooley
Biomolecules 4 (4), 1045-1069, 2014
802014
Isolation and characterisation of Ebolavirus-specific recombinant antibody fragments from murine and shark immune libraries
SA Goodchild, H Dooley, RJ Schoepp, M Flajnik, SG Lonsdale
Molecular immunology 48 (15-16), 2027-2037, 2011
772011
Diversity and repertoire of IgW and IgM VH families in the newborn nurse shark
LL Rumfelt, RL Lohr, H Dooley, MF Flajnik
BMC immunology 5, 1-15, 2004
752004
Stabilization of antibody fragments in adverse environments
H Dooley, SD Grant, WJ Harris, AJ Porter
Biotechnology and applied biochemistry 28 (1), 77-83, 1998
671998
Discovery of all three types in cartilaginous fishes enables phylogenetic resolution of the origins and evolution of interferons
AK Redmond, J Zou, CJ Secombes, DJ Macqueen, H Dooley
Frontiers in immunology 10, 467824, 2019
622019
The CXC chemokine receptors of fish: insights into CXCR evolution in the vertebrates
J Zou, AK Redmond, Z Qi, H Dooley, CJ Secombes
General and Comparative Endocrinology 215, 117-131, 2015
562015
Shark IgNAR-derived binding domains as potential diagnostic and therapeutic agents
H Matz, H Dooley
Developmental & Comparative Immunology 90, 100-107, 2019
492019
Characterization of the immunoglobulin repertoire of the spiny dogfish (Squalus acanthias)
LE Smith, K Crouch, W Cao, MR Müller, L Wu, J Steven, M Lee, M Liang, ...
Developmental & Comparative Immunology 36 (4), 665-679, 2012
482012
Humoral immune response of the small-spotted catshark, Scyliorhinus canicula
K Crouch, LE Smith, R Williams, W Cao, M Lee, A Jensen, H Dooley
Fish & shellfish immunology 34 (5), 1158-1169, 2013
432013
Antigen binding domains
H Dooley, A Porter, M Flajnik
US Patent App. 10/486,608, 2005
422005
Generation and isolation of target-specific single-domain antibodies from shark immune repertoires
MR Müller, R O’Dwyer, M Kovaleva, F Rudkin, H Dooley, CJ Barelle
Antibody Engineering: Methods and Protocols, Second Edition, 177-194, 2012
372012
Emergence of the acute-phase protein hemopexin in jawed vertebrates
H Dooley, EB Buckingham, MF Criscitiello, MF Flajnik
Molecular immunology 48 (1-3), 147-152, 2010
332010
Noncoordinate expression of J‐chain and B limp‐1 define nurse shark plasma cell populations during ontogeny
CD Castro, Y Ohta, H Dooley, MF Flajnik
European journal of immunology 43 (11), 3061-3075, 2013
322013
Phylotranscriptomics suggests the jawed vertebrate ancestor could generate diverse helper and regulatory T cell subsets
AK Redmond, DJ Macqueen, H Dooley
BMC Evolutionary Biology 18, 1-19, 2018
272018
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