| Caspases in cell death, inflammation, and pyroptosis S Kesavardhana, RKS Malireddi, TD Kanneganti Annual review of immunology 38, 567-595, 2020 | 571 | 2020 |
| ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways T Kuriakose, SM Man, RK Subbarao Malireddi, R Karki, S Kesavardhana, ... Science immunology 1 (2), aag2045-aag2045, 2016 | 545 | 2016 |
| DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome P Samir, S Kesavardhana, DM Patmore, S Gingras, RKS Malireddi, ... Nature 573 (7775), 590-594, 2019 | 294 | 2019 |
| IRGB10 liberates bacterial ligands for sensing by the AIM2 and caspase-11-NLRP3 inflammasomes SM Man, R Karki, M Sasai, DE Place, S Kesavardhana, J Temirov, ... Cell 167 (2), 382-396. e17, 2016 | 280 | 2016 |
| ZBP1 and TAK1: master regulators of NLRP3 inflammasome/pyroptosis, apoptosis, and necroptosis (PAN-optosis) RKS Malireddi, S Kesavardhana, TD Kanneganti Frontiers in cellular and infection microbiology 9, 406, 2019 | 276 | 2019 |
| Identification of the PANoptosome: a molecular platform triggering pyroptosis, apoptosis, and necroptosis (PANoptosis) S Christgen, M Zheng, S Kesavardhana, R Karki, RKS Malireddi, ... Frontiers in cellular and infection microbiology 10, 237, 2020 | 266 | 2020 |
| Mechanisms governing inflammasome activation, assembly and pyroptosis induction S Kesavardhana, TD Kanneganti International Immunology 29 (5), 201-210, 2017 | 220 | 2017 |
| Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease RK Malireddi, P Gurung, S Kesavardhana, P Samir, A Burton, ... Journal of Experimental Medicine 217 (3), 2020 | 211 | 2020 |
| NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer R Karki, SM Man, RKS Malireddi, S Kesavardhana, Q Zhu, AR Burton, ... Nature 540 (7634), 583-587, 2016 | 177 | 2016 |
| ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death S Kesavardhana, T Kuriakose, CS Guy, P Samir, RKS Malireddi, A Mishra, ... Journal of Experimental Medicine 214 (8), 2217-2229, 2017 | 140 | 2017 |
| ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis) B Banoth, S Tuladhar, R Karki, BR Sharma, B Briard, S Kesavardhana, ... Journal of Biological Chemistry 295 (52), 18276-18283, 2020 | 105 | 2020 |
| The Zα2 domain of ZBP1 is a molecular switch regulating influenza-induced PANoptosis and perinatal lethality during development S Kesavardhana, RKS Malireddi, AR Burton, SN Porter, P Vogel, ... Journal of Biological Chemistry 295 (24), 8325-8330, 2020 | 103 | 2020 |
| RIPK1 distinctly regulates yersinia-induced inflammatory cell death, PANoptosis RK Malireddi, S Kesavardhana, R Karki, B Kancharana, AR Burton, ... Immunohorizons 4 (12), 789-796, 2020 | 84 | 2020 |
| Stabilizing the native trimer of HIV-1 Env by destabilizing the heterodimeric interface of the gp41 postfusion six-helix bundle S Kesavardhana, R Varadarajan Journal of Virology 88 (17), 9590-9604, 2014 | 47 | 2014 |
| DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response S Kesavardhana, P Samir, M Zheng, RKS Malireddi, R Karki, BR Sharma, ... Journal of Biological Chemistry 296, 2021 | 38 | 2021 |
| Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity U Rathore, P Saha, S Kesavardhana, AA Kumar, R Datta, ... Journal of Biological Chemistry 292 (24), 10197-10219, 2017 | 37 | 2017 |
| A trimeric HIV-1 envelope gp120 immunogen induces potent and broad anti-V1V2 loop antibodies against HIV-1 in rabbits and rhesus macaques AT Jones, V Chamcha, S Kesavardhana, X Shen, D Beaumont, R Das, ... Journal of Virology 92 (5), 10.1128/jvi. 01796-17, 2018 | 34 | 2018 |
| Immunogen design for HIV-1 and influenza U Rathore, S Kesavardhana, VVA Mallajosyula, R Varadarajan Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (11), 1891-1906, 2014 | 32 | 2014 |
| Designed cyclic permutants of HIV-1 gp120: implications for envelope trimer structure and immunogen design P Saha, S Bhattacharyya, S Kesavardhana, ER Miranda, PSS Ali, ... Biochemistry 51 (9), 1836-1847, 2012 | 25 | 2012 |
| ZBP1: A STARGᐰTE to decode the biology of Z-nucleic acids in disease S Kesavardhana, TD Kanneganti Journal of Experimental Medicine 217 (7), 2020 | 24 | 2020 |
