Asymmetric mode of Ca2+-S100A4 interaction with nonmuscle myosin IIA generates nanomolar affinity required for filament remodeling PR Elliott, AF Irvine, HS Jung, K Tozawa, MW Pastok, R Picone, ... Structure 20 (4), 654-666, 2012 | 62 | 2012 |
Differential regulation of G1 CDK complexes by the Hsp90-Cdc37 chaperone system ST Hallett, MW Pastok, RML Morgan, A Wittner, KLIM Blundell, I Felletar, ... Cell reports 21 (5), 1386-1398, 2017 | 60 | 2017 |
Structural variability of the ubiquitin specific protease DUSP-UBL double domains PR Elliott, H Liu, MW Pastok, GJ Grossmann, DJ Rigden, MJ Clague, ... FEBS letters 585 (21), 3385-3390, 2011 | 31 | 2011 |
Mutational analysis of CDKN2A gene in a group of 390 larynx cancer patients K Kiwerska, M Rydzanicz, A Kram, M Pastok, A Antkowiak, W Domagała, ... Molecular biology reports 37, 325-332, 2010 | 16 | 2010 |
Discriminative SKP2 interactions with CDK-cyclin complexes support a cyclin A-specific role in p27KIP1 degradation M Salamina, BC Montefiore, M Liu, DJ Wood, R Heath, JR Ault, LZ Wang, ... Journal of molecular biology 433 (5), 166795, 2021 | 12 | 2021 |
Structural diversity of the cAMP-dependent protein kinase regulatory subunit in Caenorhabditis elegans MW Pastok, MC Prescott, C Dart, P Murray, HH Rees, MJ Fisher Cellular signalling 25 (1), 168-177, 2013 | 12 | 2013 |
Design and synthesis of small-molecule inhibitors targeting the SCFSKP2 E3 ligase and the MDMX-p53 interaction for cancer therapy AE Shouksmith Newcastle University, 2015 | 2 | 2015 |
Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a O Burbidge, MW Pastok, SL Hodder, G Zenkevičiūtė, MEM Noble, ... bioRxiv, 2021.07. 01.450670, 2021 | 1 | 2021 |
Design and synthesis of anti-tumour agents targeting Sulf2 and MDMX: p53 A Bertoli Newcastle University, 2015 | 1 | 2015 |
Investigating the in vivo dynamics of FtsZ and FtsZ-interacting proteins using vertical cell imaging by nanostructured immobilisation (VerCINI) CS Jukes Newcastle University, 2021 | | 2021 |
Structural and functional characterisation of cyclin-dependent kinase 6-cyclin D complexes ST Hallett Newcastle University, 2017 | | 2017 |
Design, synthesis and biological evaluation of small-molecules targeting the Mdmx-p53 interaction and the Atad2 bromodomain for cancer therapy S Adhikari Newcastle University, 2016 | | 2016 |
Structure-based design and synthesis of inhibitors of the mitotic kinases Nek2 and CDK2 H Lebraud Newcastle University, 2015 | | 2015 |
Analysis of binary interactions between OTUB1 and E2 ubiquitin-conjugating enzymes N Zulkifle University of Liverpool, 2012 | | 2012 |
Classical-style MAD phasing with wavelength interleaving and kappa goniometry on PROXIMA-1 G Bricogne, C Vonrhein, P Keller, A Thompson, P Legrand, C Cambillau, ... Acta Crystallographica Section A 68, s18-s18, 2012 | | 2012 |
Isoforms of the Protein Kinase a Regulatory Subunit in the Nematode Caenorhabditis elegans MW Pastok PQDT-UK & Ireland, 2010 | | 2010 |
Oral Lectures–MS 4: Phasing challenges. Bootstrapping from a poor start G Bricognea, C Vonrheina, P Kellera, A Thompsonb, P Legrandb, ... synchrotron radiation 254, 51-58, 0 | | |
Regulation of the Cell Cycle: Characterisation of the L Orton, J Endicott, M Pastok | | |
Supplemental Information ST Hallett, MW Pastok, RML Morgan, A Wittner, K LIM, IF Blundell, ... | | |