| Rapid identification of P-glycoprotein substrates and inhibitors C Chang, PM Bahadduri, JE Polli, PW Swaan, S Ekins Drug metabolism and disposition 34 (12), 1976-1984, 2006 | 187 | 2006 |
| Human pregnane X receptor antagonists and agonists define molecular requirements for different binding sites S Ekins, C Chang, S Mani, MD Krasowski, EJ Reschly, M Iyer, ... Molecular pharmacology 72 (3), 592-603, 2007 | 174 | 2007 |
| Structural determinants of P-glycoprotein-mediated transport of glucocorticoids CR Yates, C Chang, JD Kearbey, K Yasuda, EG Schuetz, DD Miller, ... Pharmaceutical research 20, 1794-1803, 2003 | 145 | 2003 |
| Pharmacophore-based discovery of ligands for drug transporters C Chang, S Ekins, P Bahadduri, PW Swaan Advanced drug delivery reviews 58 (12-13), 1431-1450, 2006 | 139 | 2006 |
| Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hOCT2 and rbOCT2 WM Suhre, S Ekins, C Chang, PW Swaan, SH Wright Molecular pharmacology 67 (4), 1067-1077, 2005 | 115 | 2005 |
| A ligand-based approach to identify quantitative structure− activity relationships for the androgen receptor CE Bohl, C Chang, ML Mohler, J Chen, DD Miller, PW Swaan, JT Dalton Journal of medicinal chemistry 47 (15), 3765-3776, 2004 | 105 | 2004 |
| Comparative pharmacophore modeling of organic anion transporting polypeptides: a meta-analysis of rat Oatp1a1 and human OATP1B1 C Chang, KS Pang, PW Swaan, S Ekins Journal of Pharmacology and Experimental Therapeutics 314 (2), 533-541, 2005 | 101 | 2005 |
| Computational approaches to modeling drug transporters C Chang, PW Swaan European Journal of Pharmaceutical Sciences 27 (5), 411-424, 2006 | 93 | 2006 |
| Plasma protein binding of challenging compounds K Riccardi, S Cawley, PD Yates, C Chang, C Funk, M Niosi, J Lin, L Di Journal of pharmaceutical sciences 104 (8), 2627-2636, 2015 | 92 | 2015 |
| In Vitro and Pharmacophore-Based Discovery of Novel hPEPT1 Inhibitors S Ekins, JS Johnston, P Bahadduri, VM D’Souza, A Ray, C Chang, ... Pharmaceutical research 22, 512-517, 2005 | 88 | 2005 |
| Molecular requirements of the human nucleoside transporters hCNT1, hCNT2, and hENT1 C Chang, PW Swaan, LY Ngo, PY Lum, SD Patil, JD Unadkat Molecular pharmacology 65 (3), 558-570, 2004 | 88 | 2004 |
| Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2) EY Zhang, MA Phelps, A Banerjee, CM Khantwal, C Chang, F Helsper, ... Biochemistry 43 (36), 11380-11392, 2004 | 84 | 2004 |
| Computational models to assign biopharmaceutics drug disposition classification from molecular structure A Khandelwal, PM Bahadduri, C Chang, JE Polli, PW Swaan, S Ekins Pharmaceutical research 24, 2249-2262, 2007 | 82 | 2007 |
| In vitro–in vivo correlation for low-clearance compounds using hepatocyte relay method L Di, K Atkinson, CC Orozco, C Funk, H Zhang, TS McDonald, B Tan, J Lin, ... Drug Metabolism and Disposition 41 (12), 2018-2023, 2013 | 67 | 2013 |
| Modeling and validating chronic pharmacological manipulation of circadian rhythms JK Kim, DB Forger, M Marconi, D Wood, A Doran, T Wager, C Chang, ... CPT: pharmacometrics & systems pharmacology 2 (7), 1-11, 2013 | 59 | 2013 |
| Electrophysiological characterization and modeling of the structure activity relationship of the human concentrative nucleoside transporter 3 (hCNT3) H Hu, CJ Endres, C Chang, NS Umapathy, EW Lee, YJ Fei, S Itagaki, ... Molecular pharmacology 69 (5), 1542-1553, 2006 | 59 | 2006 |
| Site-directed mutagenesis and use of bile acid− MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2) A Banerjee, A Ray, C Chang, PW Swaan Biochemistry 44 (24), 8908-8917, 2005 | 45 | 2005 |
| Application of data mining approaches to drug delivery S Ekins, J Shimada, C Chang Advanced drug delivery reviews 58 (12-13), 1409-1430, 2006 | 42 | 2006 |
| Quantitative PK–PD model-based translational pharmacology of a novel kappa opioid receptor antagonist between rats and humans C Chang, W Byon, Y Lu, LK Jacobsen, LL Badura, A Sawant-Basak, ... The AAPS journal 13, 565-575, 2011 | 40 | 2011 |
| In silico strategies for modeling membrane transporter function C Chang, A Ray, P Swaan Drug discovery today 10 (9), 663-671, 2005 | 40 | 2005 |
