Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial S Palfi, JM Gurruchaga, GS Ralph, H Lepetit, S Lavisse, PC Buttery, ... The Lancet 383 (9923), 1138-1146, 2014 | 543 | 2014 |
Characterizing mild cognitive impairment in incident Parkinson disease: the ICICLE-PD study AJ Yarnall, DP Breen, GW Duncan, TK Khoo, SY Coleman, MJ Firbank, ... Neurology 82 (4), 308-316, 2014 | 502 | 2014 |
Sleep and circadian rhythm regulation in early Parkinson disease DP Breen, R Vuono, U Nawarathna, K Fisher, JM Shneerson, AB Reddy, ... JAMA neurology 71 (5), 589-595, 2014 | 454 | 2014 |
S erum immune markers and disease progression in an incident P arkinson's disease cohort (ICICLE‐PD) CH Williams‐Gray, R Wijeyekoon, AJ Yarnall, RA Lawson, DP Breen, ... Movement disorders 31 (7), 995-1003, 2016 | 299 | 2016 |
Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's G Liu, B Boot, JJ Locascio, IE Jansen, S Winder‐Rhodes, S Eberly, ... Annals of neurology 80 (5), 674-685, 2016 | 274 | 2016 |
Cognitive decline and quality of life in incident Parkinson's disease: the role of attention RA Lawson, AJ Yarnall, GW Duncan, DP Breen, TK Khoo, ... Parkinsonism & related disorders 27, 47-53, 2016 | 244 | 2016 |
Bioinformatics-based identification of expanded repeats: a non-reference intronic pentamer expansion in RFC1 causes CANVAS H Rafehi, DJ Szmulewicz, MF Bennett, NLM Sobreira, K Pope, KR Smith, ... The American Journal of Human Genetics 105 (1), 151-165, 2019 | 237 | 2019 |
Gut–brain axis and the spread of α‐synuclein pathology: vagal highway or dead end? DP Breen, GM Halliday, AE Lang Movement disorders 34 (3), 307-316, 2019 | 216 | 2019 |
Genetic impact on cognition and brain function in newly diagnosed Parkinson’s disease: ICICLE-PD study C Nombela, JB Rowe, SE Winder-Rhodes, A Hampshire, AM Owen, ... Brain 137 (10), 2743-2758, 2014 | 200 | 2014 |
Severity of mild cognitive impairment in early Parkinson's disease contributes to poorer quality of life RA Lawson, AJ Yarnall, GW Duncan, TK Khoo, DP Breen, RA Barker, ... Parkinsonism & related disorders 20 (10), 1071-1075, 2014 | 185 | 2014 |
Prediction of cognition in Parkinson's disease with a clinical–genetic score: a longitudinal analysis of nine cohorts G Liu, JJ Locascio, JC Corvol, B Boot, Z Liao, K Page, D Franco, K Burke, ... The Lancet Neurology 16 (8), 620-629, 2017 | 164 | 2017 |
Genetic risk of Parkinson disease and progression: an analysis of 13 longitudinal cohorts H Iwaki, C Blauwendraat, HL Leonard, G Liu, J Maple-Grødem, JC Corvol, ... Neurology: Genetics 5 (4), e348, 2019 | 154 | 2019 |
Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease G Hudson, M Nalls, JR Evans, DP Breen, S Winder-Rhodes, KE Morrison, ... Neurology 80 (22), 2042-2048, 2013 | 152 | 2013 |
The Addenbrooke's Cognitive Examination for the differential diagnosis and longitudinal assessment of patients with parkinsonian disorders T Rittman, BC Ghosh, P McColgan, DP Breen, J Evans, CH Williams-Gray, ... Journal of Neurology, Neurosurgery & Psychiatry 84 (5), 544-551, 2013 | 140 | 2013 |
Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts H Iwaki, C Blauwendraat, HL Leonard, JJ Kim, G Liu, J Maple‐Grødem, ... Movement Disorders 34 (12), 1839-1850, 2019 | 128 | 2019 |
Pharmacogenetic association with adverse drug reactions to azathioprine immunosuppressive therapy following liver transplantation DP Breen, AM Marinaki, M Arenas, PC Hayes Liver transplantation 11 (7), 826-833, 2005 | 122 | 2005 |
Driving and dementia DA Breen, DP Breen, JW Moore, PA Breen, D O'Neill BMJ 334 (7608), 1365-1369, 2007 | 110 | 2007 |
Stability of mild cognitive impairment in newly diagnosed Parkinson's disease RA Lawson, AJ Yarnall, GW Duncan, DP Breen, TK Khoo, ... Journal of Neurology, Neurosurgery & Psychiatry 88 (8), 648-652, 2017 | 101 | 2017 |
Neuroendocrine abnormalities in Parkinson's disease E De Pablo-Fernández, DP Breen, PM Bouloux, RA Barker, T Foltynie, ... Journal of Neurology, Neurosurgery & Psychiatry 88 (2), 176-185, 2017 | 101 | 2017 |
Determinants of delayed diagnosis in Parkinson’s disease DP Breen, JR Evans, K Farrell, C Brayne, RA Barker Journal of Neurology 260, 1978-1981, 2013 | 97 | 2013 |