Kalesh Karunakaran
Kalesh Karunakaran
Teesside University, National Horizons Centre, UK
Verified email at - Homepage
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Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action
YK Wong, C Xu, KA Kalesh, Y He, Q Lin, WSF Wong, HM Shen, J Wang
Medicinal research reviews 37 (6), 1492-1517, 2017
Key cell signaling pathways modulated by zerumbone: role in the prevention and treatment of cancer
R Prasannan, KA Kalesh, MK Shanmugam, A Nachiyappan, ...
Biochemical pharmacology 84 (10), 1268-1276, 2012
Target identification of natural and traditional medicines with quantitative chemical proteomics approaches
J Wang, L Gao, YM Lee, KA Kalesh, YS Ong, J Lim, JE Jee, H Sun, ...
Pharmacology & Therapeutics 162, 10-22, 2016
Global profiling of protein lipidation using chemical proteomic technologies
EW Tate, KA Kalesh, T Lanyon-Hogg, EM Storck, E Thinon
Current opinion in chemical biology 24, 48-57, 2015
The quest for novel antimicrobial compounds: emerging trends in research, development, and technologies
PK Mantravadi, KA Kalesh, RCJ Dobson, AO Hudson, A Parthasarathy
Antibiotics 8 (1), 8, 2019
High-throughput synthesis of azide libraries suitable for direct “click” chemistry and in situ screening
R Srinivasan, LP Tan, H Wu, PY Yang, KA Kalesh, SQ Yao
Organic & Biomolecular Chemistry 7 (9), 1821-1828, 2009
High-Throughput Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (MptpB) Inhibitors Using Click Chemistry
LP Tan, H Wu, PY Yang, KA Kalesh, X Zhang, M Hu, R Srinivasan, ...
Organic Letters 11 (22), 5102-5105, 2009
The use of click chemistry in the emerging field of catalomics
KA Kalesh, H Shi, J Ge, SQ Yao
Organic & Biomolecular Chemistry 8 (8), 1749-1762, 2010
Peptide-based activity-based probes (ABPs) for target-specific profiling of protein tyrosine phosphatases (PTPs)
KA Kalesh, LP Tan, K Lu, L Gao, J Wang, SQ Yao
Chemical communications 46 (4), 589-591, 2010
Methods of using click chemistry in the discovery of enzyme inhibitors
R Srinivasan, J Li, SL Ng, KA Kalesh, SQ Yao
Nature Protocols 2 (11), 2655-2664, 2007
Rapid synthesis of Abelson tyrosine kinase inhibitors using click chemistry
KA Kalesh, K Liu, SQ Yao
Organic & Biomolecular Chemistry 7 (24), 5129-5136, 2009
Small molecule probes that target Abl kinase
KA Kalesh, DSB Sim, J Wang, K Liu, Q Lin, SQ Yao
Chemical communications 46 (7), 1118-1120, 2010
Target profiling of zerumbone using a novel cell-permeable clickable probe and quantitative chemical proteomics
KA Kalesh, JA Clulow, EW Tate
Chemical communications 51 (25), 5497-5500, 2015
An integrated chemical proteomics approach for quantitative profiling of intracellular ADP-ribosylation
K Kalesh, S Lukauskas, AJ Borg, AP Snijders, V Ayyappan, AKL Leung, ...
Scientific reports 9 (1), 6655, 2019
Recent advances in synthesis and identification of cyclic peptides for bioapplications
Y Siang Ong, L Gao, K A Kalesh, Z Yu, J Wang, C Liu, Y Li, H Sun, ...
Current topics in medicinal chemistry 17 (20), 2302-2318, 2017
Click Chemistry as a High‐Throughput Amenable Platform in Catalomics
KA Kalesh, PY Yang, R Srinivasan, SQ Yao
QSAR & Combinatorial Science 26 (11‐12), 1135-1144, 2007
Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane
JA Clulow, EM Storck, T Lanyon-Hogg, KA Kalesh, LH Jones, EW Tate
Chemical communications 53 (37), 5182-5185, 2017
Defeating the trypanosomatid trio: proteomics of the protozoan parasites causing neglected tropical diseases
A Parthasarathy, K Kalesh
RSC Medicinal Chemistry 11, 625-645, 2020
A capillary electrophoresis method to explore the self‐assembly of a novel polypeptide ligand with quantum dots
J Wang, C Zhang, L Liu, KA Kalesh, L Qiu, S Ding, M Fu, L Gao, P Jiang
Electrophoresis 37 (15-16), 2156-2162, 2016
An Improved Mechanism‐Based Cross‐Linker for Multiplexed Kinase Detection and Inhibition in a Complex Proteome
K Liu, KA Kalesh, L Bing Ong, SQ Yao
ChemBioChem 9 (12), 1883-1888, 2008
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