Sophie Hambleton
Sophie Hambleton
Professor of Paediatrics and Immunology, Newcastle University
Verified email at newcastle.ac.uk - Homepage
TitleCited byYear
Rapid effector function in CD8+ memory T cells
A Lalvani, R Brookes, S Hambleton, WJ Britton, AVS Hill, AJ McMichael
Journal of Experimental Medicine 186 (6), 859-865, 1997
7421997
IRF8 mutations and human dendritic-cell immunodeficiency
S Hambleton, S Salem, J Bustamante, V Bigley, S Boisson-Dupuis, ...
New England Journal of Medicine 365 (2), 127-138, 2011
4362011
Early-onset stroke and vasculopathy associated with mutations in ADA2
Q Zhou, D Yang, AK Ombrello, AV Zavialov, C Toro, AV Zavialov, ...
New England Journal of Medicine 370 (10), 911-920, 2014
3452014
Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency
RE Dickinson, H Griffin, V Bigley, LN Reynard, R Hussain, M Haniffa, ...
Blood 118 (10), 2656-2658, 2011
3102011
A robust model for read count data in exome sequencing experiments and implications for copy number variant calling
V Plagnol, J Curtis, M Epstein, KY Mok, E Stebbings, S Grigoriadou, ...
Bioinformatics 28 (21), 2747-2754, 2012
2762012
The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency
V Bigley, M Haniffa, S Doulatov, XN Wang, R Dickinson, N McGovern, ...
Journal of Experimental Medicine 208 (2), 227-234, 2011
2442011
Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations
JD Milner, TP Vogel, L Forbes, CA Ma, A Stray-Pedersen, JE Niemela, ...
Blood 125 (4), 591-599, 2015
2392015
Preventing varicella-zoster disease
S Hambleton, AA Gershon
Clinical Microbiology Reviews 18 (1), 70-80, 2005
1992005
Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an …
D Moratto, S Giliani, C Bonfim, E Mazzolari, A Fischer, HD Ochs, AJ Cant, ...
Blood 118 (6), 1675-1684, 2011
1952011
Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
S Okada, JG Markle, EK Deenick, F Mele, D Averbuch, M Lagos, ...
Science 349 (6248), 606-613, 2015
1852015
Whole-exome-sequencing-based discovery of human FADD deficiency
A Bolze, M Byun, D McDonald, NV Morgan, A Abhyankar, L Premkumar, ...
The American Journal of Human Genetics 87 (6), 873-881, 2010
1572010
The evolution of cellular deficiency in GATA2 mutation
RE Dickinson, P Milne, L Jardine, S Zandi, SI Swierczek, N McGovern, ...
Blood 123 (6), 863-874, 2014
1412014
Structural and functional properties of the human notch-1 ligand binding region
S Hambleton, NV Valeyev, A Muranyi, V Knott, JM Werner, AJ McMichael, ...
Structure 12 (12), 2173-2183, 2004
1302004
Human dendritic cell deficiency: the missing ID?
M Collin, V Bigley, M Haniffa, S Hambleton
Nature Reviews Immunology 11 (9), 575, 2011
1222011
Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience
MA Slatter, K Rao, P Amrolia, T Flood, M Abinun, S Hambleton, Z Nademi, ...
Blood 117 (16), 4367-4375, 2011
1152011
Low-strength T-cell activation promotes Th17 responses
HA Purvis, JN Stoop, J Mann, S Woods, AE Kozijn, S Hambleton, ...
Blood 116 (23), 4829-4837, 2010
1142010
Varicella zoster virus infection
AA Gershon, J Breuer, JI Cohen, RJ Cohrs, MD Gershon, D Gilden, ...
Nature reviews Disease primers 1, 15016, 2015
1022015
Localization of the delta-like-1-binding site in human Notch-1 and its modulation by calcium affinity
J Cordle, C RedfieldZ, M Stacey, PA van der Merwe, AC Willis, ...
Journal of Biological Chemistry 283 (17), 11785-11793, 2008
1022008
STAT2 deficiency and susceptibility to viral illness in humans
S Hambleton, S Goodbourn, DF Young, P Dickinson, SMB Mohamad, ...
Proceedings of the National Academy of Sciences 110 (8), 3053-3058, 2013
992013
Mutation in the TCRα subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCRαβ+ T cells
NV Morgan, S Goddard, TS Cardno, D McDonald, F Rahman, D Barge, ...
The Journal of clinical investigation 121 (2), 695-702, 2011
662011
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