| Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation E Zeqiraj, BM Filippi, M Deak, DR Alessi, DMF Van Aalten Science 326 (5960), 1707-1711, 2009 | 406 | 2009 |
| A strategy for modulation of enzymes in the ubiquitin system A Ernst, G Avvakumov, J Tong, Y Fan, Y Zhao, P Alberts, A Persaud, ... Science 339 (6119), 590-595, 2013 | 330 | 2013 |
| Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase RW Hunter, CC Hughey, L Lantier, EI Sundelin, M Peggie, E Zeqiraj, ... Nature medicine 24 (9), 1395-1406, 2018 | 288 | 2018 |
| Pseudokinases-remnants of evolution or key allosteric regulators? E Zeqiraj, DMF van Aalten Current opinion in structural biology 20 (6), 772-781, 2010 | 164 | 2010 |
| ATP and MO25α regulate the conformational state of the STRADα pseudokinase and activation of the LKB1 tumour suppressor E Zeqiraj, BM Filippi, S Goldie, I Navratilova, J Boudeau, M Deak, ... PLoS biology 7 (6), e1000126, 2009 | 161 | 2009 |
| MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases BM Filippi, P De Los Heros, Y Mehellou, I Navratilova, R Gourlay, M Deak, ... The EMBO journal 30 (9), 1730-1741, 2011 | 156 | 2011 |
| Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity H Huang, E Zeqiraj, B Dong, BK Jha, NM Duffy, S Orlicky, ... Molecular cell 53 (2), 221-234, 2014 | 145 | 2014 |
| Structure of an SspH1-PKN1 complex reveals the basis for host substrate recognition and mechanism of activation for a bacterial E3 ubiquitin ligase AFA Keszei, X Tang, C McCormick, E Zeqiraj, JR Rohde, M Tyers, ... Molecular and cellular biology 34 (3), 362-373, 2014 | 96 | 2014 |
| Emerging concepts in pseudoenzyme classification, evolution, and signaling AJM Ribeiro, S Das, N Dawson, R Zaru, S Orchard, JM Thornton, ... Science Signaling 12 (594), eaat9797, 2019 | 90 | 2019 |
| Metabolic control of BRISC–SHMT2 assembly regulates immune signalling M Walden, L Tian, RL Ross, UM Sykora, DP Byrne, EL Hesketh, ... Nature 570 (7760), 194-199, 2019 | 68 | 2019 |
| Structural basis for specificity of TGFβ family receptor small molecule inhibitors AA Ogunjimi, E Zeqiraj, DF Ceccarelli, F Sicheri, JL Wrana, L David Cellular signalling 24 (2), 476-483, 2012 | 67 | 2012 |
| Higher-order assembly of BRCC36–KIAA0157 is required for DUB activity and biological function E Zeqiraj, L Tian, CA Piggott, MC Pillon, NM Duffy, DF Ceccarelli, ... Molecular cell 59 (6), 970-983, 2015 | 59 | 2015 |
| Structural basis for the recruitment of glycogen synthase by glycogenin E Zeqiraj, X Tang, RW Hunter, M García-Rocha, A Judd, M Deak, ... Proceedings of the National Academy of Sciences 111 (28), E2831-E2840, 2014 | 57 | 2014 |
| Pseudo-DUBs as allosteric activators and molecular scaffolds of protein complexes M Walden, SK Masandi, K Pawłowski, E Zeqiraj Biochemical Society Transactions 46 (2), 453-466, 2018 | 43 | 2018 |
| Proteome analysis of metastatic colorectal cancer cells recognized by the lectin Helix pomatia agglutinin (HPA) J Saint‐Guirons, E Zeqiraj, U Schumacher, P Greenwell, M Dwek Proteomics 7 (22), 4082-4089, 2007 | 43 | 2007 |
| Getting a handle on glycogen synthase–Its interaction with glycogenin E Zeqiraj, F Sicheri Molecular aspects of medicine 46, 63-69, 2015 | 35 | 2015 |
| Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965 D Ahwazi, K Neopane, GR Markby, F Kopietz, AJ Ovens, M Dall, ... Biochemical Journal 478 (15), 2977-2997, 2021 | 34 | 2021 |
| Mechanism of glycogen synthase inactivation and interaction with glycogenin L Marr, D Biswas, LA Daly, C Browning, SCM Vial, DP Maskell, C Hudson, ... Nature communications 13 (1), 3372, 2022 | 29 | 2022 |
| Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase SN Shehata, RW Hunter, E Ohta, MW Peggie, HJ Lou, F Sicheri, E Zeqiraj, ... Cellular signalling 24 (11), 2085-2094, 2012 | 25 | 2012 |
| Expression and purification of functional human glycogen synthase-1: glycogenin-1 complex in insect cells RW Hunter, E Zeqiraj, N Morrice, F Sicheri, K Sakamoto Protein expression and purification 108, 23-29, 2015 | 13 | 2015 |
