Heather J Lee
Heather J Lee
Verified email at newcastle.edu.au
TitleCited byYear
Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity
SA Smallwood, HJ Lee, C Angermueller, F Krueger, H Saadeh, J Peat, ...
Nature methods 11 (8), 817-820, 2014
4702014
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
D Schramek, A Leibbrandt, V Sigl, L Kenner, JA Pospisilik, HJ Lee, ...
Nature 468 (7320), 98-102, 2010
4502010
FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency
G Ficz, TA Hore, F Santos, HJ Lee, W Dean, J Arand, F Krueger, D Oxley, ...
Cell stem cell 13 (3), 351-359, 2013
2982013
Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity
C Angermueller, SJ Clark, HJ Lee, IC Macaulay, MJ Teng, TX Hu, ...
Nature Methods, 2016
2422016
Reprogramming the Methylome: Erasing Memory and Creating Diversity
HJ Lee, TA Hore, W Reik
Cell Stem Cell 14 (6), 710-719, 2014
2032014
Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity
SJ Clark, HJ Lee, SA Smallwood, G Kelsey, W Reik
Genome Biology 17 (1), 1, 2016
1472016
DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning
C Angermueller, HJ Lee, W Reik, O Stegle
Genome Biology 18 (1), 67, 2017
1292017
scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells
SJ Clark, R Argelaguet, CA Kapourani, TM Stubbs, HJ Lee, ...
Nature communications 9 (1), 781, 2018
972018
Tracking the embryonic stem cell transition from ground state pluripotency
T Kalkan, N Olova, M Roode, C Mulas, HJ Lee, I Nett, H Marks, R Walker, ...
Development, dev. 142711, 2017
892017
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells
HJ Lee, D Gallego-Ortega, A Ledger, D Schramek, P Joshi, MM Szwarc, ...
Development 140 (7), 1397-1401, 2013
662013
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer
M Kalyuga, D Gallego-Ortega, HJ Lee, DL Roden, MJ Cowley, CE Caldon, ...
PLoS biology 10 (12), e1001461, 2012
592012
Insulin, a key regulator of hormone responsive milk protein synthesis during lactogenesis in murine mammary explants
KK Menzies, HJ Lee, C Lefèvre, CJ Ormandy, KL Macmillan, KR Nicholas
Functional & integrative genomics 10 (1), 87-95, 2010
552010
Allosteric activation of the extracellular Ca2+-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation
H Lee, H Mun, N Lewis, M Crouch, E Culverston, R Mason, A Conigrave
Biochem. J 404, 141-149, 2007
522007
Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq)
SJ Clark, SA Smallwood, HJ Lee, F Krueger, W Reik, G Kelsey
Nature Protocols 12 (3), 534-547, 2017
472017
Interplay between progesterone and prolactin in mammary development and implications for breast cancer
HJ Lee, CJ Ormandy
Molecular and Cellular Endocrinology 357 (1), 101-107, 2012
402012
Lineage specific methylation of the Elf5 promoter in mammary epithelial cells
HJ Lee, RA Hinshelwood, T Bouras, D Gallego‐Ortega, F Valdés‐Mora, ...
Stem Cells 29 (10), 1611-1619, 2011
342011
Elf5, hormones and cell fate
HJ Lee, CJ Ormandy
Trends in Endocrinology & Metabolism 23 (6), 292-298, 2012
312012
ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.
D Gallego-Ortega, A Ledger, DL Roden, AM Law, A Magenau, Z Kikhtyak, ...
PLoS biology 13 (12), e1002330-e1002330, 2015
252015
The antiproliferative effects of progestins in T47D breast cancer cells are tempered by progestin induction of the ETS transcription factor Elf5
HN Hilton, M Kalyuga, MJ Cowley, MC Alles, HJ Lee, CE Caldon, ...
Molecular Endocrinology 24 (7), 1380-1392, 2010
162010
Regulation of growth hormone signaling by selective estrogen receptor modulators occurs through suppression of protein tyrosine phosphatases
KC Leung, J Brce, N Doyle, HJ Lee, GM Leong, K Sjögren, KKY Ho
Endocrinology 148 (5), 2417-2423, 2007
162007
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Articles 1–20