| Modern advances in heterocyclic chemistry in drug discovery AP Taylor, RP Robinson, YM Fobian, DC Blakemore, LH Jones, O Fadeyi Organic & biomolecular chemistry 14 (28), 6611-6637, 2016 | 784 | 2016 |
| Developing irreversible inhibitors of the protein kinase cysteinome Q Liu, Y Sabnis, Z Zhao, T Zhang, SJ Buhrlage, LH Jones, NS Gray Chemistry & biology 20 (2), 146-159, 2013 | 752 | 2013 |
| Squaramides: physical properties, synthesis and applications RI Storer, C Aciro, LH Jones Chemical Society Reviews 40 (5), 2330-2346, 2011 | 634 | 2011 |
| Sulfonyl fluorides as privileged warheads in chemical biology A Narayanan, LH Jones Chemical science 6 (5), 2650-2659, 2015 | 513 | 2015 |
| Target validation using chemical probes ME Bunnage, ELP Chekler, LH Jones Nature chemical biology 9 (4), 195-199, 2013 | 473 | 2013 |
| Antibody catalysis of the oxidation of water P Wentworth Jr, LH Jones, AD Wentworth, X Zhu, NA Larsen, IA Wilson, ... Science 293 (5536), 1806-1811, 2001 | 364 | 2001 |
| Broad-spectrum kinase profiling in live cells with lysine-targeted sulfonyl fluoride probes Q Zhao, X Ouyang, X Wan, KS Gajiwala, JC Kath, LH Jones, ... Journal of the American Chemical Society 139 (2), 680-685, 2017 | 346 | 2017 |
| Antibodies have the intrinsic capacity to destroy antigens AD Wentworth, LH Jones, P Wentworth Jr, KD Janda, RA Lerner Proceedings of the National Academy of Sciences 97 (20), 10930-10935, 2000 | 287 | 2000 |
| Applications of chemogenomic library screening in drug discovery LH Jones, ME Bunnage Nature reviews Drug discovery 16 (4), 285-296, 2017 | 198 | 2017 |
| Physicochemical drug properties associated with in vivo toxicological outcomes: a review DA Price, J Blagg, L Jones, N Greene, T Wager Expert opinion on drug metabolism & toxicology 5 (8), 921-931, 2009 | 185 | 2009 |
| Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes EC Hett, H Xu, KF Geoghegan, A Gopalsamy, RE Kyne Jr, CA Menard, ... ACS Chemical Biology 10 (4), 1094-1098, 2015 | 183 | 2015 |
| Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition JB Telliez, ME Dowty, L Wang, J Jussif, T Lin, L Li, E Moy, P Balbo, W Li, ... ACS chemical biology 11 (12), 3442-3451, 2016 | 169 | 2016 |
| Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay J Hall, A Brault, F Vincent, S Weng, H Wang, D Dumlao, A Aulabaugh, ... PLoS One 12 (9), e0184843, 2017 | 147 | 2017 |
| Labeling preferences of diazirines with protein biomolecules AV West, G Muncipinto, HY Wu, AC Huang, MT Labenski, LH Jones, ... Journal of the American Chemical Society 143 (17), 6691-6700, 2021 | 144 | 2021 |
| Small molecules targeting hepatitis C virus-encoded NS5A cause subcellular redistribution of their target: insights into compound modes of action P Targett-Adams, EJS Graham, J Middleton, A Palmer, SM Shaw, ... Journal of virology 85 (13), 6353-6368, 2011 | 142 | 2011 |
| Emerging utility of fluorosulfate chemical probes LH Jones ACS Medicinal Chemistry Letters 9 (7), 584-586, 2018 | 131 | 2018 |
| Recent advances in the molecular design of synthetic vaccines LH Jones Nature chemistry 7 (12), 952-960, 2015 | 124 | 2015 |
| Oxaziridine-mediated amination of primary amines: Scope and application to a one-pot pyrazole synthesis A Armstrong, LH Jones, JD Knight, RD Kelsey Organic Letters 7 (4), 713-716, 2005 | 124 | 2005 |
| Molecular scaffolds using multiple orthogonal conjugations: applications in chemical biology and drug discovery DM Beal, LH Jones Angewandte Chemie International Edition 51 (26), 6320-6326, 2012 | 122 | 2012 |
| Know your target, know your molecule ME Bunnage, AM Gilbert, LH Jones, EC Hett Nature chemical biology 11 (6), 368-372, 2015 | 120 | 2015 |
Yogesh SabnisUCB BiopharmaVerified email at ucb.com
Yogesh SabnisUCB BiopharmaVerified email at ucb.com