Damien Downes
Damien Downes
Verified email at ndcls.ox.ac.uk
Title
Cited by
Cited by
Year
Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo
LLP Hanssen, MT Kassouf, AM Oudelaar, D Biggs, C Preece, DJ Downes, ...
Nature cell biology 19 (8), 952-961, 2017
792017
Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains
AM Oudelaar, JOJ Davies, LLP Hanssen, JM Telenius, R Schwessinger, ...
Nature genetics 50 (12), 1744-1751, 2018
512018
Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia
S Mettananda, CA Fisher, D Hay, M Badat, L Quek, K Clark, P Hublitz, ...
Nature communications 8 (1), 1-11, 2017
372017
Characterization of the mutagenic spectrum of 4-nitroquinoline 1-oxide (4-NQO) in Aspergillus nidulans by whole genome sequencing
DJ Downes, M Chonofsky, K Tan, BT Pfannenstiel, SL Reck-Peterson, ...
G3: Genes, Genomes, Genetics 4 (12), 2483-2492, 2014
302014
Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo
CS Simon, DJ Downes, ME Gosden, J Telenius, DR Higgs, JR Hughes, ...
Development 144 (7), 1249-1260, 2017
212017
Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA
CC Hunter, KS Siebert, DJ Downes, KH Wong, SD Kreutzberger, ...
Eukaryotic cell 13 (4), 527-538, 2014
202014
Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C
AM Oudelaar, JOJ Davies, DJ Downes, DR Higgs, JR Hughes
Nucleic acids research 45 (22), e184-e184, 2017
152017
Regulation of the NADP-glutamate dehydrogenase gene gdhA in Aspergillus nidulans by the Zn (II) 2Cys6 transcription factor LeuB
DJ Downes, MA Davis, SD Kreutzberger, BL Taig, RB Todd
Microbiology 159 (12), 2467-2480, 2013
142013
Impaired DNA demethylation of C/EBP sites causes premature aging
A Schäfer, B Mekker, M Mallick, V Vastolo, E Karaulanov, D Sebastian, ...
Genes & development 32 (11-12), 742-762, 2018
132018
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation
L Godfrey, NT Crump, R Thorne, IJ Lau, E Repapi, D Dimou, AL Smith, ...
Nature communications 10 (1), 1-15, 2019
122019
Spatial differentiation of gene expression in Aspergillus niger colony grown for sugar beet pulp utilization
I Benoit, M Zhou, AV Duarte, DJ Downes, RB Todd, W Kloezen, H Post, ...
Scientific reports 5 (1), 1-13, 2015
82015
Dual DNA binding and coactivator functions of Aspergillus nidulans TamA, a Zn(II)2Cys6 transcription factor
DJ Downes, MA Davis, KH Wong, SD Kreutzberger, MJ Hynes, RB Todd
Molecular microbiology 92 (6), 1198-1211, 2014
82014
Low-input capture-C: a chromosome conformation capture assay to analyze chromatin architecture in small numbers of cells
AM Oudelaar, DJ Downes, JOJ Davies, JR Hughes
Bio-protocol 7 (23), 2017
62017
High-Throughput Genotyping of CRISPR/Cas Edited Cells in 96-Well Plates
L Nussbaum, JM Telenius, S Hill, PP Hirschfeld, MC Suciu, DJ Downes, ...
Methods and protocols 1 (3), 29, 2018
32018
Tri-C
AM Oudelaar, JR Hughes, DJ Downes
22019
Enhancers Predominantly Regulate Gene Expression in vivo Via Transcription Initiation
MSC Larke, T Nojima, J Telenius, JA Sharpe, JA Sloane-Stanley, S Butler, ...
12019
An integrated platform to systematically identify causal variants and genes for polygenic human traits.
DJ Downes, R Schwessinger, SJ Hill, L Nussbaum, C Scott, ME Gosden, ...
bioRxiv, 813618, 2019
12019
Genotype of IFITM3 Promoter SNP, Associated with Influenza Severity, Found to Affect Chromatin Interactions and Accessibility
EK Allen, JC Crawford, D Downes, JR Hughes, PG Thomas
D34. INFECTIONS AND THE IMMUNE RESPONSE, A6528-A6528, 2020
2020
Absolute quantification of transcription factors reveals principles of gene regulation in erythropoiesis
MA Gillespie, CG Palii, D Sanchez-Taltavull, P Shannon, ...
Molecular cell, 2020
2020
Targeted high-resolution chromosome conformation capture at genome-wide scale
DJ Downes, ME Gosden, J Telenius, SJ Carpenter, L Nussbaum, ...
bioRxiv, 2020
2020
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Articles 1–20