| Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis AL Astier, G Meiffren, S Freeman, DA Hafler The Journal of clinical investigation 116 (12), 3252-3257, 2006 | 352 | 2006 |
| The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after β1-integrin stimulation in B cells and binds to p130cas A Astier, H Avraham, SN Manie, J Groopman, T Canty, S Avraham, ... Journal of Biological Chemistry 272 (1), 228-232, 1997 | 263 | 1997 |
| Measles virus induces functional TRAIL production by human dendritic cells PO Vidalain, O Azocar, B Lamouille, A Astier, C Rabourdin-Combe, ... Journal of virology 74 (1), 556-559, 2000 | 240 | 2000 |
| Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell–induced inflammation JC Marie, AL Astier, P Rivailler, C Rabourdin-Combe, TF Wild, B Horvat Nature immunology 3 (7), 659-666, 2002 | 209 | 2002 |
| Cutting edge: CD46, a new costimulatory molecule for T cells, that induces p120CBL and LAT phosphorylation A Astier, MC Trescol-Biémont, O Azocar, B Lamouille, ... The Journal of Immunology 164 (12), 6091-6095, 2000 | 189 | 2000 |
| HpARI protein secreted by a helminth parasite suppresses interleukin-33 M Osbourn, DC Soares, F Vacca, ES Cohen, IC Scott, WF Gregory, ... Immunity 47 (4), 739-751. e5, 2017 | 165 | 2017 |
| CD46/CD3 costimulation induces morphological changes of human T cells and activation of Vav, Rac, and extracellular signal-regulated kinase mitogen-activated protein kinase Y Zaffran, O Destaing, A Roux, S Ory, T Nheu, P Jurdic, ... The Journal of Immunology 167 (12), 6780-6785, 2001 | 142 | 2001 |
| Involvement of p130Cas and p105HEF1, a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on … SN Manié, ARP Beck, A Astier, SF Law, T Canty, H Hirai, BJ Druker, ... Journal of Biological Chemistry 272 (7), 4230-4236, 1997 | 139 | 1997 |
| The related adhesion focal tyrosine kinase differentially phosphorylates p130Cas and the Cas-like protein, p105HEF1 A Astier, SN Manié, H Avraham, H Hirai, SF Law, Y Zhang, EA Golemis, ... Journal of Biological Chemistry 272 (32), 19719-19724, 1997 | 132 | 1997 |
| Complement as a regulator of adaptive immunity J Killick, G Morisse, D Sieger, AL Astier Seminars in immunopathology 40, 37-48, 2018 | 117 | 2018 |
| Abnormal Tr1 differentiation in multiple sclerosis AL Astier, DA Hafler Journal of neuroimmunology 191 (1-2), 70-78, 2007 | 104 | 2007 |
| Soluble Fcγ receptors WH Fridman, JL Teillaud, C Bouchard, C Teillaud, A Astier, E Tartour, ... Journal of Leucocyte Biology 54 (5), 504-512, 1993 | 101 | 1993 |
| Human epidermal Langerhans cells secrete a soluble receptor for IgG (Fc gamma RII/CD32) that inhibits the binding of immune complexes to Fc gamma R+ cells. A Astier, H De la Salle, C De la Salle, T Bieber, ME Esposito-Farese, ... Journal of immunology (Baltimore, Md.: 1950) 152 (1), 201-212, 1994 | 80 | 1994 |
| Increased IL-23 secretion and altered chemokine production by dendritic cells upon CD46 activation in patients with multiple sclerosis A Vaknin-Dembinsky, G Murugaiyan, DA Hafler, AL Astier, HL Weiner Journal of neuroimmunology 195 (1-2), 140-145, 2008 | 75 | 2008 |
| T‐cell regulation by CD46 and its relevance in multiple sclerosis AL Astier Immunology 124 (2), 149-154, 2008 | 66 | 2008 |
| The dynamic processing of CD46 intracellular domains provides a molecular rheostat for T cell activation S Ni Choileain, NJ Weyand, C Neumann, J Thomas, M So, AL Astier PloS one 6 (1), e16287, 2011 | 65 | 2011 |
| Temporal gene expression profile of human precursor B leukemia cells induced by adhesion receptor: identification of pathways regulating B-cell survival AL Astier, R Xu, M Svoboda, E Hinds, O Munoz, R de Beaumont, ... Blood, The Journal of the American Society of Hematology 101 (3), 1118-1127, 2003 | 65 | 2003 |
| Regulation of integrin-mediated p130Cas tyrosine phosphorylation in human B cells: a role for p59Fyn and SHP2 SN Manié, A Astier, N Haghayeghi, T Canty, BJ Druker, H Hirai, ... Journal of Biological Chemistry 272 (25), 15636-15641, 1997 | 62 | 1997 |
| TGFβ-mediated activation of Smad1 in B-cell non-Hodgkin's lymphoma and effect on cell proliferation O Munoz, F Fend, R De Beaumont, H Husson, A Astier, AS Freedman Leukemia 18 (12), 2015-2025, 2004 | 57 | 2004 |
| Natural and recombinant soluble low-affinity FcγR: detection, purification, and functional activities JL Teillaud, C Bouchard, A Astier, C Teillaud, E Tartour, J Michon, ... Immunomethods 4 (1), 48-64, 1994 | 54 | 1994 |
David HaflerProfessor of Neurology and Immunobiology, Yale UniversityVerified email at yale.edu
