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Douglas P Dyer
Douglas P Dyer
Verified email at manchester.ac.uk - Homepage
Title
Cited by
Cited by
Year
TSG-6 inhibits neutrophil migration via direct interaction with the chemokine CXCL8
DP Dyer, JM Thomson, A Hermant, TA Jowitt, TM Handel, AEI Proudfoot, ...
The Journal of Immunology 192 (5), 2177-2185, 2014
2192014
The extracellular matrix and the immune system: A mutually dependent relationship
TE Sutherland, DP Dyer, JE Allen
Science 379 (6633), eabp8964, 2023
1982023
Immunomodulation by radiotherapy in tumour control and normal tissue toxicity
UM Cytlak, DP Dyer, J Honeychurch, KJ Williams, MA Travis, TM Illidge
Nature Reviews Immunology 22 (2), 124-138, 2022
1492022
Chemokine receptor redundancy and specificity are context dependent
DP Dyer, L Medina-Ruiz, R Bartolini, F Schuette, CE Hughes, K Pallas, ...
Immunity 50 (2), 378-389. e5, 2019
1282019
The anti-inflammatory protein TSG-6 regulates chemokine function by inhibiting chemokine/glycosaminoglycan interactions
DP Dyer, CL Salanga, SC Johns, E Valdambrini, MM Fuster, CM Milner, ...
Journal of Biological Chemistry 291 (24), 12627-12640, 2016
1202016
The dependence of chemokine–glycosaminoglycan interactions on chemokine oligomerization
DP Dyer, CL Salanga, BF Volkman, T Kawamura, TM Handel
Glycobiology 26 (3), 312-326, 2016
1152016
Cytokines and growth factors cross-link heparan sulfate
E Migliorini, D Thakar, J Kühnle, R Sadir, DP Dyer, Y Li, C Sun, ...
Open biology 5 (8), 150046, 2015
822015
A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function
VA Higman, DC Briggs, DJ Mahoney, CD Blundell, BM Sattelle, DP Dyer, ...
Journal of Biological Chemistry 289 (9), 5619-5634, 2014
612014
Understanding the mechanisms that facilitate specificity, not redundancy, of chemokine‐mediated leukocyte recruitment
DP Dyer
Immunology 160 (4), 336-344, 2020
582020
Multiple glycosaminoglycan-binding epitopes of monocyte chemoattractant protein-3/CCL7 enable it to function as a non-oligomerizing chemokine
CL Salanga, DP Dyer, JG Kiselar, S Gupta, MR Chance, TM Handel
Journal of Biological Chemistry 289 (21), 14896-14912, 2014
492014
Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization
DP Dyer, E Migliorini, CL Salanga, D Thakar, TM Handel, RP Richter
Open biology 7 (1), 160286, 2017
432017
Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates
R Karlsson, P Chopra, A Joshi, Z Yang, SY Vakhrushev, TM Clausen, ...
Science advances 7 (52), eabl6026, 2021
422021
Kinetics of CXCL12 binding to atypical chemokine receptor 3 reveal a role for the receptor N terminus in chemokine binding
M Gustavsson, DP Dyer, C Zhao, TM Handel
Science signaling 12 (598), eaaw3657, 2019
392019
Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors
AL Gray, R Karlsson, ARE Roberts, AJL Ridley, N Pun, B Khan, ...
Cell reports 42 (1), 2023
362023
Identification of the pharmacophore of the CC chemokine-binding proteins Evasin-1 and-4 using phage display
P Bonvin, SM Dunn, F Rousseau, DP Dyer, J Shaw, CA Power, ...
Journal of Biological Chemistry 289 (46), 31846-31855, 2014
342014
Role of extracellular matrix proteoglycans in immune cell recruitment
AL Gray, N Pun, AJL Ridley, DP Dyer
International Journal of Experimental Pathology 103 (2), 34-43, 2022
322022
CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses
DP Dyer, K Pallas, L Medina-Ruiz, F Schuette, GJ Wilson, GJ Graham
Scientific Reports 7 (1), 42681, 2017
292017
Perspectives on the biological role of chemokine: glycosaminoglycan interactions
TM Handel, DP Dyer
Journal of Histochemistry & Cytochemistry 69 (2), 87-91, 2021
212021
Increased circulating chemokines and macrophage recruitment in growing vestibular schwannomas
CJ Hannan, D Lewis, C O'Leary, M Waqar, D Brough, KN Couper, ...
Neurosurgery 92 (3), 581-589, 2023
202023
Analysis of combinatorial chemokine receptor expression dynamics using multi-receptor reporter mice
L Medina-Ruiz, R Bartolini, GJ Wilson, DP Dyer, F Vidler, CE Hughes, ...
Elife 11, e72418, 2022
202022
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