TSG-6 inhibits neutrophil migration via direct interaction with the chemokine CXCL8 DP Dyer, JM Thomson, A Hermant, TA Jowitt, TM Handel, AEI Proudfoot, ... The Journal of Immunology 192 (5), 2177-2185, 2014 | 219 | 2014 |
The extracellular matrix and the immune system: A mutually dependent relationship TE Sutherland, DP Dyer, JE Allen Science 379 (6633), eabp8964, 2023 | 198 | 2023 |
Immunomodulation by radiotherapy in tumour control and normal tissue toxicity UM Cytlak, DP Dyer, J Honeychurch, KJ Williams, MA Travis, TM Illidge Nature Reviews Immunology 22 (2), 124-138, 2022 | 149 | 2022 |
Chemokine receptor redundancy and specificity are context dependent DP Dyer, L Medina-Ruiz, R Bartolini, F Schuette, CE Hughes, K Pallas, ... Immunity 50 (2), 378-389. e5, 2019 | 128 | 2019 |
The anti-inflammatory protein TSG-6 regulates chemokine function by inhibiting chemokine/glycosaminoglycan interactions DP Dyer, CL Salanga, SC Johns, E Valdambrini, MM Fuster, CM Milner, ... Journal of Biological Chemistry 291 (24), 12627-12640, 2016 | 120 | 2016 |
The dependence of chemokine–glycosaminoglycan interactions on chemokine oligomerization DP Dyer, CL Salanga, BF Volkman, T Kawamura, TM Handel Glycobiology 26 (3), 312-326, 2016 | 115 | 2016 |
Cytokines and growth factors cross-link heparan sulfate E Migliorini, D Thakar, J Kühnle, R Sadir, DP Dyer, Y Li, C Sun, ... Open biology 5 (8), 150046, 2015 | 82 | 2015 |
A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function VA Higman, DC Briggs, DJ Mahoney, CD Blundell, BM Sattelle, DP Dyer, ... Journal of Biological Chemistry 289 (9), 5619-5634, 2014 | 61 | 2014 |
Understanding the mechanisms that facilitate specificity, not redundancy, of chemokine‐mediated leukocyte recruitment DP Dyer Immunology 160 (4), 336-344, 2020 | 58 | 2020 |
Multiple glycosaminoglycan-binding epitopes of monocyte chemoattractant protein-3/CCL7 enable it to function as a non-oligomerizing chemokine CL Salanga, DP Dyer, JG Kiselar, S Gupta, MR Chance, TM Handel Journal of Biological Chemistry 289 (21), 14896-14912, 2014 | 49 | 2014 |
Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization DP Dyer, E Migliorini, CL Salanga, D Thakar, TM Handel, RP Richter Open biology 7 (1), 160286, 2017 | 43 | 2017 |
Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates R Karlsson, P Chopra, A Joshi, Z Yang, SY Vakhrushev, TM Clausen, ... Science advances 7 (52), eabl6026, 2021 | 42 | 2021 |
Kinetics of CXCL12 binding to atypical chemokine receptor 3 reveal a role for the receptor N terminus in chemokine binding M Gustavsson, DP Dyer, C Zhao, TM Handel Science signaling 12 (598), eaaw3657, 2019 | 39 | 2019 |
Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors AL Gray, R Karlsson, ARE Roberts, AJL Ridley, N Pun, B Khan, ... Cell reports 42 (1), 2023 | 36 | 2023 |
Identification of the pharmacophore of the CC chemokine-binding proteins Evasin-1 and-4 using phage display P Bonvin, SM Dunn, F Rousseau, DP Dyer, J Shaw, CA Power, ... Journal of Biological Chemistry 289 (46), 31846-31855, 2014 | 34 | 2014 |
Role of extracellular matrix proteoglycans in immune cell recruitment AL Gray, N Pun, AJL Ridley, DP Dyer International Journal of Experimental Pathology 103 (2), 34-43, 2022 | 32 | 2022 |
CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses DP Dyer, K Pallas, L Medina-Ruiz, F Schuette, GJ Wilson, GJ Graham Scientific Reports 7 (1), 42681, 2017 | 29 | 2017 |
Perspectives on the biological role of chemokine: glycosaminoglycan interactions TM Handel, DP Dyer Journal of Histochemistry & Cytochemistry 69 (2), 87-91, 2021 | 21 | 2021 |
Increased circulating chemokines and macrophage recruitment in growing vestibular schwannomas CJ Hannan, D Lewis, C O'Leary, M Waqar, D Brough, KN Couper, ... Neurosurgery 92 (3), 581-589, 2023 | 20 | 2023 |
Analysis of combinatorial chemokine receptor expression dynamics using multi-receptor reporter mice L Medina-Ruiz, R Bartolini, GJ Wilson, DP Dyer, F Vidler, CE Hughes, ... Elife 11, e72418, 2022 | 20 | 2022 |