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Yongxu Lu
Yongxu Lu
Department of Pathology, Unviersity of Cambridge
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease
Y Peng, SL Felce, D Dong, F Penkava, AJ Mentzer, X Yao, G Liu, Z Yin, ...
Nature immunology 23 (1), 50-61, 2022
1392022
How does vaccinia virus interfere with interferon?
GL Smith, C Talbot-Cooper, Y Lu
Advances in virus research 100, 355-378, 2018
652018
Vaccinia virus protein C6 inhibits type I IFN signalling in the nucleus and binds to the transactivation domain of STAT2
JH Stuart, RP Sumner, Y Lu, JS Snowden, GL Smith
PLoS pathogens 12 (12), e1005955, 2016
652016
Histone deacetylase 4 promotes type I interferon signaling, restricts DNA viruses, and is degraded via vaccinia virus protein C6
Y Lu, JH Stuart, C Talbot-Cooper, S Agrawal-Singh, B Huntly, AI Smid, ...
Proceedings of the National Academy of Sciences 116 (24), 11997-12006, 2019
632019
Quantitative temporal proteomic analysis of vaccinia virus infection reveals regulation of histone deacetylases by an interferon antagonist
L Soday, Y Lu, JD Albarnaz, CTR Davies, R Antrobus, GL Smith, ...
Cell reports 27 (6), 1920-1933. e7, 2019
602019
The replication defect of ICP0-null mutant herpes simplex virus 1 can be largely complemented by the combined activities of human cytomegalovirus proteins IE1 and pp71
RD Everett, AJ Bell, Y Lu, A Orr
Journal of virology 87 (2), 978-990, 2013
362013
An overview of current knowledge of deadly CoVs and their interface with innate immunity
Y Zhang, S Gargan, Y Lu, NJ Stevenson
Viruses 13 (4), 560, 2021
202021
Stimulation of the replication of ICP0-null mutant herpes simplex virus 1 and pp71-deficient human cytomegalovirus by epstein-barr virus tegument protein BNRF1
Y Lu, A Orr, RD Everett
Journal of Virology 90 (21), 9664-9673, 2016
142016
Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins
Y Lu, HA Michel, PH Wang, GL Smith
Frontiers in microbiology 13, 1027015, 2022
122022
Analysis of the functional interchange between the IE1 and pp71 proteins of human cytomegalovirus and ICP0 of herpes simplex virus 1
Y Lu, RD Everett
Journal of Virology 89 (6), 3062-3075, 2015
122015
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity
H Stewart, Y Lu, S O’Keefe, A Valpadashi, LD Cruz-Zaragoza, HA Michel, ...
Iscience 26 (11), 108080, 2023
82023
TRIM5α restricts poxviruses and is antagonized by CypA and the viral protein C6
Y Zhao, Y Lu, S Richardson, M Sreekumar, JD Albarnaz, GL Smith
Nature 620 (7975), 873-880, 2023
82023
DDX50 is a viral restriction factor that enhances IRF3 activation
MA Pallett, Y Lu, GL Smith
Viruses 14 (2), 316, 2022
82022
Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination
Z Yin, JL Chen, Y Lu, B Wang, L Godfrey, AJ Mentzer, X Yao, G Liu, ...
Cell reports 42 (5), 2023
22023
HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus
Y Lu, Y Zhao, C Gao, S Suresh, J Men, A Sawyers, GL Smith
Cell Reports 43 (3), 2024
2024
Filamin B restricts vaccinia virus spread and is targeted by vaccinia virus protein C4
I Georgana, SR Scutts, C Gao, Y Lu, AA Torres, H Ren, E Emmott, J Men, ...
Journal of Virology, e01485-23, 2024
2024
DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation. Viruses 2022, 14, 316
MA Pallett, Y Lu, GL Smith
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2022
2022
Inhibition of IFN-gamma signalling by vaccinia virus protein C6: a multi-functional interferon antagonist
C Talbot-Cooper, Y Lu, J Stewart, G Smith
Access Microbiology 1 (1A), 795, 2019
2019
Functional comparison of regulatory proteins expressed by different Herpes viruses
Y Lu
University of Glasgow, 2015
2015
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Articles 1–19