Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development U Marx, T Akabane, TB Andersson, E Baker, M Beilmann, S Beken, ... Altex, 2020 | 218 | 2020 |
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery B Zimmer, G Pallocca, N Dreser, S Foerster, T Waldmann, J Westerhout, ... Archives of toxicology 88 (5), 1109-1126, 2014 | 79 | 2014 |
Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology C Rovida, T Barton-Maclaren, E Benfenati, F Caloni, C Chandrasekera, ... Alternatives to Animal Experimentation: ALTEX 37 (4), 579-606, 2020 | 71 | 2020 |
miRNA expression profiling in a human stem cell-based model as a tool for developmental neurotoxicity testing G Pallocca, M Fabbri, MG Sacco, L Gribaldo, D Pamies, I Laurenza, ... Cell biology and toxicology 29 (4), 239-257, 2013 | 68 | 2013 |
Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data A Krebs, T Waldmann, MF Wilks, BMA van Vugt-Lussenburg, ... ALTEX-Alternatives to animal experimentation 36 (4), 682-699, 2019 | 65 | 2019 |
Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration G Pallocca, M Grinberg, M Henry, T Frickey, JG Hengstler, T Waldmann, ... Archives of toxicology 90 (1), 159-180, 2016 | 51 | 2016 |
Harnessing the power of novel animal-free test methods for the development of COVID-19 drugs and vaccines F Busquet, T Hartung, G Pallocca, C Rovida, M Leist Archives of toxicology, 1-10, 2020 | 45 | 2020 |
Setting the stage for next-generation risk assessment with non-animal approaches: The EU-ToxRisk project experience MJ Moné, G Pallocca, SE Escher, T Exner, M Herzler, SH Bennekou, ... Archives of toxicology 94 (10), 3581-3592, 2020 | 40 | 2020 |
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods A Krebs, BMA van Vugt-Lussenburg, T Waldmann, W Albrecht, J Boei, ... Archives of toxicology, 1-27, 2020 | 40 | 2020 |
A human pluripotent carcinoma stem cell-based model for in vitro developmental neurotoxicity testing: effects of methylmercury, lead and aluminum evaluated by gene expression … I Laurenza, G Pallocca, M Mennecozzi, B Scelfo, D Pamies, A Bal-Price International Journal of Developmental Neuroscience 31 (7), 679-691, 2013 | 40 | 2013 |
Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling N Dreser, B Zimmer, C Dietz, E Sügis, G Pallocca, J Nyffeler, J Meisig, ... Neurotoxicology 50, 56-70, 2015 | 39 | 2015 |
Next-generation risk assessment of chemicals–Rolling out a human-centric testing strategy to drive 3R implementation: The RISK-HUNT3R project perspective G Pallocca, MJ Moné, H Kamp, M Luijten, B Van de Water, M Leist ALTEX-Alternatives to animal experimentation 39 (3), 419-426, 2022 | 31 | 2022 |
Determination of benchmark concentrations and their statistical uncertainty for cytotoxicity test data and functional in vitro assays A Krebs, J Nyffeler, C Karreman, BZ Schmidt, F Kappenberg, J Mellert, ... Alternatives to Animal Experimentation: ALTEX, 2019 | 24 | 2019 |
Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay M Colaianna, S Ilmjärv, H Peterson, I Kern, S Julien, M Baquié, ... Archives of toxicology 91 (1), 365-391, 2017 | 21 | 2017 |
The rise of Three Rs centres and platforms in Europe W Neuhaus, B Reininger-Gutmann, B Rinner, R Plasenzotti, ... Alternatives to Laboratory Animals 50 (2), 90-120, 2022 | 17 | 2022 |
Impairment of human neural crest cell migration by prolonged exposure to interferon-beta G Pallocca, J Nyffeler, X Dolde, M Grinberg, G Gstraunthaler, T Waldmann, ... Archives of toxicology 91 (10), 3385-3402, 2017 | 15 | 2017 |
On the usefulness of animals as a model system (part I): Overview of criteria and focus on robustness G Pallocca, C Rovida, M Leist Alternatives to Animal Experimentation: ALTEX 39 (2), 347-353, 2022 | 11 | 2022 |
Changes in miRNA expression profiling during neuronal differentiation and methyl mercury-induced toxicity in human in vitro models G Pallocca, M Fabbri, S Nerini-Molteni, F Pistollato, D Zagoura, MG Sacco, ... Toxics 2 (3), 443-463, 2014 | 9 | 2014 |
On the usefulness of animals as a model system (part II): Considering benefits within distinct use domains G Pallocca, M Leist Alternatives to Animal Experimentation: ALTEX 39 (3), 531-539, 2022 | 8 | 2022 |
The current status and work of Three Rs centres and platforms in Europe W Neuhaus, B Reininger-Gutmann, B Rinner, R Plasenzotti, ... Alternatives to Laboratory Animals 50 (6), 381-413, 2022 | 5 | 2022 |