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Martin Swarbrick
Martin Swarbrick
Director R&D Chemistry, Ryvu Therapeutics SA
Verified email at ryvu.com
Title
Cited by
Cited by
Year
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance
D Zatreanu, HMR Robinson, O Alkhatib, M Boursier, H Finch, L Geo, ...
Nature communications 12 (1), 3636, 2021
1822021
Fragment-based hit identification: thinking in 3D
AD Morley, A Pugliese, K Birchall, J Bower, P Brennan, N Brown, ...
Drug Discovery Today 18 (23-24), 1221-1227, 2013
1742013
Enantioselective Baeyer–Villiger Oxidation Catalyzed by Palladium(II) Complexes with Chiral P,N-Ligands
AV Malkov, F Friscourt, M Bell, ME Swarbrick, P Kocovský
The Journal of Organic Chemistry 73 (11), 3996-4003, 2008
982008
Alkyl Substituent Effects on Pipecolyl Amide Isomer Equilibrium: Efficient Methodology for Synthesizing Enantiopure 6-Alkylpipecolic Acids and Conformational Analysis of Their …
ME Swarbrick, F Gosselin, WD Lubell
The Journal of Organic Chemistry 64 (6), 1993-2002, 1999
741999
Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB2 agonists for the treatment of inflammatory pain
RJ Gleave, PJ Beswick, AJ Brown, GMP Giblin, P Goldsmith, CP Haslam, ...
Bioorganic & medicinal chemistry letters 20 (2), 465-468, 2010
562010
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression
JRP Knight, C Alexandrou, GL Skalka, N Vlahov, K Pennel, L Officer, ...
Cancer discovery 11 (5), 1228-1247, 2021
532021
The aza-[2, 3]-Wittig sigmatropic rearrangement of acyclic amines: Scope and limitations of silicon assistance
JC Anderson, A Flaherty, ME Swarbrick
The Journal of Organic Chemistry 65 (26), 9152-9156, 2000
422000
Efficient nitrogen transfer from aldehyde-derived N-acyloxaziridines
A Armstrong, ID Edmonds, ME Swarbrick
Tetrahedron letters 44 (28), 5335-5338, 2003
392003
The Silicon-Assisted Aza-(2, 3)-Wittig Sigmatropic Rearrangement
JC Anderson, DC Siddons, SC Smith, ME Swarbrick
Journal of organic chemistry 61, 4820-4823, 1996
391996
Electrophilic amination of enolates with oxaziridines: effects of oxaziridine structure and reaction conditions
A Armstrong, ID Edmonds, ME Swarbrick, NR Treweeke
Tetrahedron 61 (35), 8423-8442, 2005
372005
Potent, selective small molecule inhibitors of type III phosphatidylinositol-4-kinase α-but not β-inhibit the phosphatidylinositol signaling cascade and cancer cell proliferation
MJ Waring, DM Andrews, PF Faulder, V Flemington, JC McKelvie, ...
Chemical communications 50 (40), 5388-5390, 2014
322014
New monoterpene-derived phosphinopyridine ligands and their application in the enantioselective iridium-catalyzed hydrogenation
G Chelucci, M Marchetti, AV Malkov, F Friscourt, ME Swarbrick, ...
Tetrahedron 67 (30), 5421-5431, 2011
282011
Identification of [4-[4-(methylsulfonyl) phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors
ME Swarbrick, PJ Beswick, RJ Gleave, RH Green, S Bingham, C Bountra, ...
Bioorganic & medicinal chemistry letters 19 (15), 4504-4508, 2009
222009
Indole derivatives
DA Demaine, GMP Giblin, RE Hosking, GGA Inglis, XQ Lewell, ...
US Patent 7,288,564, 2007
21*2007
Indole derivatives
DA Demaine, GMP Giblin, RE Hosking, GGA Inglis, XQ Lewell, ...
US Patent 7,288,564, 2007
21*2007
Indole derivatives
DA Demaine, GMP Giblin, RE Hosking, GGA Inglis, XQ Lewell, ...
US Patent 7,288,564, 2007
21*2007
Indole derivatives
DA Demaine, GMP Giblin, RE Hosking, GGA Inglis, XQ Lewell, ...
US Patent 7,288,564, 2007
21*2007
Cox-2 inhibiting pyridine derivatives
P Beswick, N Pegg, M Swarbrick, J Skidmore, S Modi
US Patent 7,446,117, 2008
192008
Cox-2 inhibiting pyridine derivatives
P Beswick, N Pegg, M Swarbrick, J Skidmore, S Modi
US Patent 7,446,117, 2008
192008
Cox-2 inhibiting pyridine derivatives
P Beswick, N Pegg, M Swarbrick, J Skidmore, S Modi
US Patent 7,446,117, 2008
192008
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