Resolving the fibrotic niche of human liver cirrhosis at single-cell level P Ramachandran, R Dobie, JR Wilson-Kanamori, EF Dora, ... Nature 575 (7783), 512-518, 2019 | 1218 | 2019 |
Fibrosis: from mechanisms to medicines NC Henderson, F Rieder, TA Wynn Nature 587 (7835), 555-566, 2020 | 1158 | 2020 |
Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs NC Henderson, TD Arnold, Y Katamura, MM Giacomini, JD Rodriguez, ... Nature medicine 19 (12), 1617-1624, 2013 | 909 | 2013 |
Galectin-3 regulates myofibroblast activation and hepatic fibrosis NC Henderson, AC Mackinnon, SL Farnworth, F Poirier, FP Russo, ... Proceedings of the National Academy of Sciences 103 (13), 5060-5065, 2006 | 763 | 2006 |
Regulation of alternative macrophage activation by galectin-3 AC MacKinnon, SL Farnworth, PS Hodkinson, NC Henderson, ... The Journal of Immunology 180 (4), 2650-2658, 2008 | 697 | 2008 |
Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis NC Henderson, AC Mackinnon, SL Farnworth, T Kipari, C Haslett, ... The American journal of pathology 172 (2), 288-298, 2008 | 682 | 2008 |
The regulation of inflammation by galectin‐3 NC Henderson, T Sethi Immunological reviews 230 (1), 160-171, 2009 | 674 | 2009 |
Decoding myofibroblast origins in human kidney fibrosis C Kuppe, MM Ibrahim, J Kranz, X Zhang, S Ziegler, J Perales-Patón, ... Nature 589 (7841), 281-286, 2021 | 525 | 2021 |
Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis T Tsukui, KH Sun, JB Wetter, JR Wilson-Kanamori, LA Hazelwood, ... Nature communications 11 (1), 1920, 2020 | 484 | 2020 |
Liver fibrosis: cellular mechanisms of progression and resolution NC Henderson, JP Iredale Clinical Science 112 (5), 265-280, 2007 | 436 | 2007 |
Differential abundance testing on single-cell data using k-nearest neighbor graphs E Dann, NC Henderson, SA Teichmann, MD Morgan, JC Marioni Nature biotechnology 40 (2), 245-253, 2022 | 409 | 2022 |
Modeling liver fibrosis in rodents C Constandinou, N Henderson, JP Iredale Fibrosis Research: Methods and Protocols, 237-250, 2005 | 373 | 2005 |
Single-cell transcriptomics uncovers zonation of function in the mesenchyme during liver fibrosis R Dobie, JR Wilson-Kanamori, BEP Henderson, JR Smith, KP Matchett, ... Cell reports 29 (7), 1832-1847. e8, 2019 | 333 | 2019 |
Extracellular matrix degradation in liver fibrosis: biochemistry and regulation JP Iredale, A Thompson, NC Henderson Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (7), 876-883, 2013 | 329 | 2013 |
Eosinophils secrete IL-4 to facilitate liver regeneration YPS Goh, NC Henderson, JE Heredia, A Red Eagle, JI Odegaard, ... Proceedings of the National Academy of Sciences 110 (24), 9914-9919, 2013 | 265 | 2013 |
Integrin-mediated regulation of TGFβ in fibrosis NC Henderson, D Sheppard Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (7), 891-896, 2013 | 225 | 2013 |
PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis K Martin, J Pritchett, J Llewellyn, AF Mullan, VS Athwal, R Dobie, ... Nature communications 7 (1), 12502, 2016 | 224 | 2016 |
Critical role of c-jun (NH2) terminal kinase in paracetamol-induced acute liver failure NC Henderson, KJ Pollock, J Frew, AC Mackinnon, RA Flavell, RJ Davis, ... Gut 56 (7), 982-990, 2007 | 220 | 2007 |
Single-cell genomics and spatial transcriptomics: discovery of novel cell states and cellular interactions in liver physiology and disease biology A Saviano, NC Henderson, TF Baumert Journal of hepatology 73 (5), 1219-1230, 2020 | 215 | 2020 |
Single-cell technologies in hepatology: new insights into liver biology and disease pathogenesis P Ramachandran, KP Matchett, R Dobie, JR Wilson-Kanamori, ... Nature reviews Gastroenterology & hepatology 17 (8), 457-472, 2020 | 196 | 2020 |