| Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication A Sfeir, ST Kosiyatrakul, D Hockemeyer, SL MacRae, J Karlseder, ... Cell 138 (1), 90-103, 2009 | 1083 | 2009 |
| Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination PA Mateos-Gomez, F Gong, N Nair, KM Miller, E Lazzerini-Denchi, A Sfeir Nature 518 (7538), 254-257, 2015 | 732 | 2015 |
| 53BP1 regulates DSB repair using Rif1 to control 5′ end resection M Zimmermann, F Lottersberger, SB Buonomo, A Sfeir, T de Lange Science 339 (6120), 700-704, 2013 | 658 | 2013 |
| Removal of shelterin reveals the telomere end-protection problem A Sfeir, T De Lange Science 336 (6081), 593-597, 2012 | 650 | 2012 |
| Microhomology-mediated end joining: a back-up survival mechanism or dedicated pathway? A Sfeir, LS Symington Trends in biochemical sciences 40 (11), 701-714, 2015 | 639 | 2015 |
| POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end D Hockemeyer, AJ Sfeir, JW Shay, WE Wright, T De Lange The EMBO journal 24 (14), 2667-2678, 2005 | 427 | 2005 |
| Does a sentinel or a subset of short telomeres determine replicative senescence? Y Zou, A Sfeir, SM Gryaznov, JW Shay, WE Wright Molecular biology of the cell 15 (8), 3709-3718, 2004 | 359 | 2004 |
| Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal A Sfeir, S Kabir, M van Overbeek, GB Celli, T de Lange Science 327 (5973), 1657-1661, 2010 | 340 | 2010 |
| Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells Y Zhao, AJ Sfeir, Y Zou, CM Buseman, TT Chow, JW Shay, WE Wright Cell 138 (3), 463-475, 2009 | 299 | 2009 |
| Telomere-end processing: the terminal nucleotidesof human chromosomes AJ Sfeir, W Chai, JW Shay, WE Wright Molecular cell 18 (1), 131-138, 2005 | 298 | 2005 |
| Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance M Tigano, DC Vargas, S Tremblay-Belzile, Y Fu, A Sfeir Nature 591 (7850), 477-481, 2021 | 206 | 2021 |
| Stop pulling my strings—what telomeres taught us about the DNA damage response E Lazzerini-Denchi, A Sfeir Nature reviews Molecular cell biology 17 (6), 364-378, 2016 | 193 | 2016 |
| The helicase domain of Polθ counteracts RPA to promote alt-NHEJ PA Mateos-Gomez, T Kent, SK Deng, S McDevitt, E Kashkina, TM Hoang, ... Nature structural & molecular biology 24 (12), 1116-1123, 2017 | 173 | 2017 |
| ATM and ATR signaling regulate the recruitment of human telomerase to telomeres AS Tong, JL Stern, A Sfeir, M Kartawinata, T de Lange, XD Zhu, TM Bryan Cell reports 13 (8), 1633-1646, 2015 | 149 | 2015 |
| The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G‐overhangs at human telomeres W Chai, AJ Sfeir, H Hoshiyama, JW Shay, WE Wright EMBO reports 7 (2), 225-230, 2006 | 148 | 2006 |
| Single-molecule analysis of mtDNA replication uncovers the basis of the common deletion AF Phillips, AR Millet, M Tigano, SM Dubois, H Crimmins, L Babin, ... Molecular cell 65 (3), 527-538. e6, 2017 | 123 | 2017 |
| Nontelomeric role for Rap1 in regulating metabolism and protecting against obesity F Yeung, CM Ramírez, PA Mateos-Gomez, A Pinzaru, G Ceccarini, ... Cell reports 3 (6), 1847-1856, 2013 | 112 | 2013 |
| Telomere replication stress induced by POT1 inactivation accelerates tumorigenesis AM Pinzaru, RA Hom, A Beal, AF Phillips, E Ni, T Cardozo, N Nair, J Choi, ... Cell reports 15 (10), 2170-2184, 2016 | 109 | 2016 |
| Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining T Kent, PA Mateos-Gomez, A Sfeir, RT Pomerantz Elife 5, e13740, 2016 | 104 | 2016 |
| Vps9p CUE domain ubiquitin binding is required for efficient endocytic protein traffic BA Davies, JD Topp, AJ Sfeir, DJ Katzmann, DS Carney, GG Tall, ... Journal of Biological Chemistry 278 (22), 19826-19833, 2003 | 90 | 2003 |
Jerry W. ShayUT SouthwesternVerified email at utsouthwestern.edu
