Syam Prakash Somasekharan
Syam Prakash Somasekharan
Research Scientist, Vancouver Prostate Centre
Verified email at mail.ubc.ca - Homepage
TitleCited byYear
Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization
S Montessuit, SP Somasekharan, O Terrones, S Lucken-Ardjomande, ...
Cell 142 (6), 889-901, 2010
3252010
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation
G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ...
Cell 153 (5), 1064-1079, 2013
2622013
Translational activation of HIF1α by YB-1 promotes sarcoma metastasis
AM El-Naggar, CJ Veinotte, H Cheng, TGP Grunewald, GL Negri, ...
Cancer cell 27 (5), 682-697, 2015
1292015
YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1
SP Somasekharan, A El-Naggar, G Leprivier, H Cheng, S Hajee, ...
J Cell Biol 208 (7), 913-929, 2015
922015
HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response
B Rotblat, AL Southwell, DE Ehrnhoefer, NH Skotte, M Metzler, ...
Proceedings of the National Academy of Sciences 111 (8), 3032-3037, 2014
552014
Identification and quantification of newly synthesized proteins translationally regulated by YB-1 using a novel Click–SILAC approach
SP Somasekharan, N Stoynov, B Rotblat, G Leprivier, JD Galpin, ...
Journal of proteomics 77, e1-e10, 2012
332012
TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis
SP Somasekharan, M Koc, A Morizot, O Micheau, PHB Sorensen, ...
Apoptosis 18 (3), 324-336, 2013
192013
Expression and localization of calcium-dependent protein kinase isoforms in chickpea
SRS Prakash, C Jayabaskaran
Journal of plant physiology 163 (11), 1135-1149, 2006
192006
eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response
A Jan, B Jansonius, A Delaidelli, SP Somasekharan, M Vandal, GL Negri, ...
Acta neuropathologica 133 (1), 101-119, 2017
102017
Heterologous expression and biochemical characterization of two calcium-dependent protein kinase isoforms CaCPK1 and CaCPK2 from chickpea
SRS Prakash, C Jayabaskaran
Journal of plant physiology 163 (11), 1083-1093, 2006
92006
Co-translational assembly of proteasome subunits in NOT1-containing assemblysomes
OO Panasenko, SP Somasekharan, Z Villanyi, M Zagatti, F Bezrukov, ...
Nature structural & molecular biology 26 (2), 110, 2019
62019
An Aqueous Extract of Marine Microalgae Exhibits Antimetastatic Activity through Preferential Killing of Suspended Cancer Cells and Anticolony Forming Activity
SP Somasekharan, A El-Naggar, PH Sorensen, Y Wang, H Cheng
Evidence-Based Complementary and Alternative Medicine 2016, 2016
32016
Cloning of two chickpea cDNAs encoding calcium-dependent protein kinase isoforms
SRS Prakash, C Jayabaskaran
Current Science, 72-77, 2007
22007
Stress-induced tunneling nanotubes support treatment adaptation in prostate cancer
A Kretschmer, F Zhang, SP Somasekharan, C Tse, L Leachman, A Gleave, ...
Scientific reports 9, 2019
12019
Stress-associated selective mRNA translation and sarcoma metastasis.
AM El-Naggar, S Somasekharan, H Cheng, M Pan, PH Sorensen
CLINICAL CANCER RESEARCH 24 (2), 30-30, 2018
2018
Characterizing androgen receptor blockade-and metabolic stress-induced tunneling nanotube formation supporting stress adaptivity in prostate cancer
A Kretschmer, F Zhang, C Tse, L Leachman, A Gleave, SP Somasekharan, ...
European Urology Supplements 16 (3), e254, 2017
2017
Abstract A63: YB-1 is critical for stress granule assembly and protects cells from oxidative stress
SP Somasekharan, G Leprivier, V Evdokimova, EIN Amal, S Hajee, ...
Cancer Research 74 (20 Supplement), A63-A63, 2014
2014
Cloning of two chickpea cDNAs encoding calcium-dependent protein kinase isoforms.
SR Syam Prakash, C Jayabaskaran
Current Science (00113891) 93 (1), 2007
2007
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