| Phosphodiesterase type 4 inhibition in CNS diseases A Blokland, P Heckman, T Vanmierlo, R Schreiber, D Paes, J Prickaerts Trends in Pharmacological Sciences 40 (12), 971-985, 2019 | 50 | 2019 |
| The molecular biology of phosphodiesterase 4 enzymes as pharmacological targets: an interplay of isoforms, conformational states, and inhibitors D Paes, M Schepers, B Rombaut, D van den Hove, T Vanmierlo, ... Pharmacological Reviews 73 (3), 1016-1049, 2021 | 39 | 2021 |
| Targeting phosphodiesterases—Towards a tailor-made approach in multiple sclerosis treatment M Schepers, A Tiane, D Paes, S Sanchez, B Rombaut, E Piccart, ... Frontiers in Immunology 10, 1727, 2019 | 38 | 2019 |
| Antagonizing α7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition NP van Goethem, D Paes, D Puzzo, E Fedele, C Rebosio, W Gulisano, ... Cellular Signalling 62, 109338, 2019 | 20 | 2019 |
| Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis M Schepers, D Paes, A Tiane, B Rombaut, E Piccart, L van Veggel, ... Brain, Behavior, and Immunity 109, 1-22, 2023 | 19 | 2023 |
| Increased isoform-specific phosphodiesterase 4D expression is associated with pathology and cognitive impairment in Alzheimer’s disease D Paes, R Lardenoije, RM Carollo, JAY Roubroeks, M Schepers, ... Neurobiology of Aging 97, 56-64, 2021 | 18 | 2021 |
| Early-postnatal iron deficiency impacts plasticity in the dorsal and ventral hippocampus in piglets E Nelissen, J De Vry, A Antonides, D Paes, M Schepers, FJ van der Staay, ... International Journal of Developmental Neuroscience 59, 47-51, 2017 | 15 | 2017 |
| PDE inhibition in distinct cell types to reclaim the balance of synaptic plasticity B Rombaut, S Kessels, M Schepers, A Tiane, D Paes, Y Solomina, ... Theranostics 11 (5), 2080, 2021 | 13 | 2021 |
| Inhibition of PDE2 and PDE4 synergistically improves memory consolidation processes D Paes, K Xie, DG Wheeler, D Zook, J Prickaerts, M Peters Neuropharmacology 184, 108414, 2021 | 10 | 2021 |
| Pharmacological inhibition of phosphodiesterase 7 enhances consolidation processes of spatial memory S McQuown, D Paes, K Baumgärtel, J Prickaerts, M Peters Neurobiology of learning and memory 177, 107357, 2021 | 10 | 2021 |
| Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types D Paes, S Hermans, D van den Hove, T Vanmierlo, J Prickaerts, A Carlier Biophysical Journal 121 (14), 2693-2711, 2022 | 6 | 2022 |
| Biased 5-HT1A receptor agonists F13714 and NLX-101 differentially affect pattern separation and neuronal plasticity in rats after acute and chronic treatment BTJ van Hagen, NP van Goethem, E Nelissen, D Paes, K Koymans, ... Molecular and cellular neuroscience 120, 103719, 2022 | 5 | 2022 |
| Systemic multipotent adult progenitor cells improve long-term neurodevelopmental outcomes after preterm hypoxic-ischemic encephalopathy M Barkhuizen, R Van Mechelen, M Vermeer, P Chedraui, D Paes, ... Behavioural Brain Research 362, 77-81, 2019 | 5 | 2019 |
| Soluble guanylate cyclase stimulator riociguat improves spatial memory in mice via peripheral mechanisms E Nelissen, BTJ van Hagen, EK Argyrousi, NP van Goethem, ... Neuroscience Letters 788, 136840, 2022 | 4 | 2022 |
| Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology D Paes, M Schepers, E Willems, B Rombaut, A Tiane, Y Solomina, ... Cellular and Molecular Life Sciences 80 (7), 178, 2023 | 2 | 2023 |
| Phosphodiesterase 4D inhibition boosts remyelination in multiple sclerosis M Schepers, D Paes, A Tiane, E Houben, O Bruno, C Brullo, N Hellings, ... Front Neurosci 13, 2019 | 2 | 2019 |
| Object novelty memory tests: methods, test procedures and measurements D Paes, BTJ van Hagen, J Prickaerts Handbook of Behavioral Neuroscience 27, 39-51, 2018 | 2 | 2018 |
| Beta-amyloid associates directly with PDE4D5 to activate the enzyme and reduce cAMP availability YY Sin, RT Cameron, M Schepers, R MacLeod, TA Wright, D Paes, ... FEBS Letters, 2024 | | 2024 |
| PDE4B as a key regulator of out of control microglia B Rombaut, S Kessels, C Trippaers, M Schepers, A Tiane, D Paes, ... GLIA 71, E542-E542, 2023 | | 2023 |
| Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis T Vanmierlo, M Schepers, D Paes, A Tiane, B Rombaut, E Piccart, ... GLIA 71, E1089-E1090, 2023 | | 2023 |
