| CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ... Molecular cell 46 (5), 595-605, 2012 | 737 | 2012 |
| Degenerate target sites mediate rapid primed CRISPR adaptation PC Fineran, MJH Gerritzen, M Suárez-Diez, T Künne, J Boekhorst, ... Proceedings of the National Academy of Sciences 111 (16), E1629-E1638, 2014 | 295 | 2014 |
| Cas3-derived target DNA degradation fragments fuel primed CRISPR adaptation T Künne, SN Kieper, JW Bannenberg, AIM Vogel, WR Miellet, M Klein, ... Molecular cell 63 (5), 852-864, 2016 | 138 | 2016 |
| Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex TR Blosser, L Loeff, ER Westra, M Vlot, T Künne, M Sobota, C Dekker, ... Molecular cell 58 (1), 60-70, 2015 | 117 | 2015 |
| Harnessing type I CRISPR–Cas systems for genome engineering in human cells P Cameron, MM Coons, SE Klompe, AM Lied, SC Smith, B Vidal, ... Nature biotechnology 37 (12), 1471-1477, 2019 | 109 | 2019 |
| Planting the seed: target recognition of short guide RNAs T Künne, DC Swarts, SJJ Brouns Trends in microbiology 22 (2), 74-83, 2014 | 98 | 2014 |
| Role of nucleotide identity in effective CRISPR target escape mutations T Künne, Y Zhu, F da Silva, N Konstantinides, RE McKenzie, RN Jackson, ... Nucleic acids research 46 (19), 10395-10404, 2018 | 11 | 2018 |
| Electrophoretic mobility shift assay of DNA and CRISPR-Cas ribonucleoprotein complexes T Künne, ER Westra, SJJ Brouns CRISPR: Methods and Protocols, 171-184, 2015 | 7 | 2015 |
| Modulating CRISPR-Cas genome editing using guide-complementary DNA oligonucleotides T Swartjes, P Shang, DTM Van Den Berg, T Künne, N Geijsen, ... The CRISPR Journal 5 (4), 571-585, 2022 | | 2022 |
| Off-target activity inhibitors for guided endonucleases RA Notebaart, TA Künne, SJJ Brouns, J Van Der Oost WO Patent 2,020,065,062, 2020 | | 2020 |
| Adapting to change: on the mechanism of type IE CRISPR-Cas defence TA Künne PQDT-Global, 2017 | | 2017 |
| caS3-derIved tarGet dna T Künne, SN Kieper, JW Bannenberg, AIM Vogel, WR Miellet, M Klein, ... CRISPR'S lIttle HelpeRs 63 (5), 129, 2016 | | 2016 |
| 49 Do we need a new vaccine to control the re-emergence of pertussis? AC Allen, MM Wilk, LH Slater, AE Clatworthy, DT Hung, JAG van Strijp, ... | | |
