Tim Künne
Tim Künne
Verified email at wur.nl
Cited by
Cited by
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3
ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ...
Molecular cell 46 (5), 595-605, 2012
Degenerate target sites mediate rapid primed CRISPR adaptation
PC Fineran, MJH Gerritzen, M Suárez-Diez, T Künne, J Boekhorst, ...
Proceedings of the National Academy of Sciences 111 (16), E1629-E1638, 2014
Cas3-derived target DNA degradation fragments fuel primed CRISPR adaptation
T Künne, SN Kieper, JW Bannenberg, AIM Vogel, WR Miellet, M Klein, ...
Molecular cell 63 (5), 852-864, 2016
Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex
TR Blosser, L Loeff, ER Westra, M Vlot, T Künne, M Sobota, C Dekker, ...
Molecular cell 58 (1), 60-70, 2015
Planting the seed: target recognition of short guide RNAs
T Künne, DC Swarts, SJJ Brouns
Trends in microbiology 22 (2), 74-83, 2014
Harnessing type I CRISPR–Cas systems for genome engineering in human cells
P Cameron, MM Coons, SE Klompe, AM Lied, SC Smith, B Vidal, ...
Nature biotechnology 37 (12), 1471-1477, 2019
Role of nucleotide identity in effective CRISPR target escape mutations
T Künne, Y Zhu, F da Silva, N Konstantinides, RE McKenzie, RN Jackson, ...
Nucleic acids research 46 (19), 10395-10404, 2018
Electrophoretic mobility shift assay of DNA and CRISPR-Cas ribonucleoprotein complexes
T Künne, ER Westra, SJJ Brouns
CRISPR, 171-184, 2015
caS3-derIved tarGet dna
T Künne, SN Kieper, JW Bannenberg, AIM Vogel, WR Miellet, M Klein, ...
CRISPR'S lIttle HelpeRs 63 (5), 129, 2016
49 Do we need a new vaccine to control the re-emergence of pertussis?
AC Allen, MM Wilk, LH Slater, AE Clatworthy, DT Hung, JAG van Strijp, ...
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