Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease EF Fang, Y Hou, K Palikaras, BA Adriaanse, JS Kerr, B Yang, S Lautrup, ... Nature neuroscience 22 (3), 401-412, 2019 | 1147 | 2019 |
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA PA Aas, M Otterlei, PØ Falnes, CB Vågbø, F Skorpen, M Akbari, ... Nature 421 (6925), 859-863, 2003 | 745 | 2003 |
Post‐replicative base excision repair in replication foci M Otterlei, E Warbrick, TA Nagelhus, T Haug, G Slupphaug, M Akbari, ... The EMBO journal, 1999 | 428 | 1999 |
hUNG2 is the major repair enzyme for removal of uracil from U: A matches, U: G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup B Kavli, O Sundheim, M Akbari, M Otterlei, H Nilsen, F Skorpen, PA Aas, ... Journal of Biological Chemistry 277 (42), 39926-39936, 2002 | 395 | 2002 |
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA MP Westbye, E Feyzi, PA Aas, CB Vågbø, VA Talstad, B Kavli, L Hagen, ... Journal of biological chemistry 283 (36), 25046-25056, 2008 | 203 | 2008 |
Uracil in DNA and its processing by different DNA glycosylases T Visnes, B Doseth, HS Pettersen, L Hagen, MML Sousa, M Akbari, ... Philosophical transactions of the Royal Society B: Biological sciences 364 …, 2009 | 153 | 2009 |
Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis M Akbari, T Visnes, HE Krokan, M Otterlei DNA repair 7 (4), 605-616, 2008 | 147 | 2008 |
Mitochondria in the signaling pathways that control longevity and health span M Akbari, TBL Kirkwood, VA Bohr Ageing research reviews 54, 100940, 2019 | 142 | 2019 |
Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells M Akbari, M Otterlei, J Pena-Diaz, PA Aas, B Kavli, NB Liabakk, L Hagen, ... Nucleic acids research 32 (18), 5486-5498, 2004 | 141 | 2004 |
RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity DL Croteau, ML Rossi, C Canugovi, J Tian, P Sykora, M Ramamoorthy, ... Aging cell 11 (3), 456-466, 2012 | 121 | 2012 |
Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner M Akbari, MD Hansen, J Halgunset, F Skorpen, HE Krokan The Journal of molecular diagnostics 7 (1), 36-39, 2005 | 119 | 2005 |
Genome instability in Alzheimer disease Y Hou, H Song, DL Croteau, M Akbari, VA Bohr Mechanisms of Ageing and Development 161, 83-94, 2017 | 115 | 2017 |
Properties and functions of human uracil-DNA glycosylase from the UNG gene HE Krokan, M Otterlei, H Nilsen, B Kavli, F Skorpen, S Andersen, ... Progress in nucleic acid research and molecular biology 68, 365-386, 2001 | 115 | 2001 |
DNA polymerase beta participates in mitochondrial DNA repair P Sykora, S Kanno, M Akbari, T Kulikowicz, BA Baptiste, GS Leandro, ... Molecular and cellular biology 37 (16), e00237-17, 2017 | 102 | 2017 |
XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage A Hanssen‐Bauer, K Solvang‐Garten, O Sundheim, J Peña‐Diaz, ... Environmental and molecular mutagenesis 52 (8), 623-635, 2011 | 94 | 2011 |
Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity M Akbari, J Peña-Diaz, S Andersen, NB Liabakk, M Otterlei, HE Krokan DNA repair 8 (7), 834-843, 2009 | 73 | 2009 |
X-ray repair cross complementing protein 1 in base excision repair A Hanssen-Bauer, K Solvang-Garten, M Akbari, M Otterlei International journal of molecular sciences 13 (12), 17210-17229, 2012 | 70 | 2012 |
Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes M Akbari, K Solvang-Garten, A Hanssen-Bauer, NV Lieske, HS Pettersen, ... DNA repair 9 (7), 785-795, 2010 | 69 | 2010 |
Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress M Akbari, M Otterlei, J Pena-Diaz, HE Krokan Neuroscience 145 (4), 1201-1212, 2007 | 66 | 2007 |
The rate of base excision repair of uracil is controlled by the initiating glycosylase T Visnes, M Akbari, L Hagen, G Slupphaug, HE Krokan DNA repair 7 (11), 1869-1881, 2008 | 58 | 2008 |