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Susanne N. Wijesinghe
Susanne N. Wijesinghe
Verified email at bham.ac.uk
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Year
Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets
DE Nanus, A Badoume, SN Wijesinghe, AM Halsey, P Hurley, Z Ahmed, ...
EBioMedicine 72, 2021
682021
Regulation of the inflammatory synovial fibroblast phenotype by metastasis‐associated lung adenocarcinoma transcript 1 long noncoding RNA in obese patients with osteoarthritis
DE Nanus, SN Wijesinghe, MJ Pearson, MR Hadjicharalambous, ...
Arthritis & rheumatology 72 (4), 609-619, 2020
582020
Involvements of long noncoding RNAs in obesity‐associated inflammatory diseases
SN Wijesinghe, T Nicholson, K Tsintzas, SW Jones
Obesity reviews 22 (4), e13156, 2021
402021
A novel form of JARID2 is required for differentiation in lineage‐committed cells
D Al‐Raawi, R Jones, S Wijesinghe, J Halsall, M Petric, S Roberts, ...
The EMBO journal 38 (3), e98449, 2019
232019
Differential metabotypes in synovial fibroblasts and synovial fluid in hip osteoarthritis patients support inflammatory responses
H Farah, SN Wijesinghe, T Nicholson, F Alnajjar, M Certo, A Alghamdi, ...
International journal of molecular sciences 23 (6), 3266, 2022
192022
Oligonucleotide therapies in the treatment of arthritis: a narrative review
SN Wijesinghe, MA Lindsay, SW Jones
Biomedicines 9 (8), 902, 2021
142021
A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1
R Jones, S Wijesinghe, C Wilson, J Halsall, T Liloglou, A Kanhere
Iscience 24 (4), 2021
112021
Obesity defined molecular endotypes in the synovium of patients with osteoarthritis provides a rationale for therapeutic targeting of fibroblast subsets
SN Wijesinghe, A Badoume, DE Nanus, A Sharma‐Oates, H Farah, ...
Clinical and Translational Medicine 13 (4), e1232, 2023
102023
The expression and function of metastases associated lung adenocarcinoma transcript-1 long non-coding RNA in subchondral bone and osteoblasts from patients with osteoarthritis
FA Alnajjar, A Sharma-Oates, SN Wijesinghe, H Farah, DE Nanus, ...
Cells 10 (4), 786, 2021
82021
Novel gene variants in patients with platelet‐based bleeding using combined exome sequencing and RNAseq murine expression data
AO Khan, RJ Stapley, JA Pike, SN Wijesinghe, JS Reyat, I Almazni, ...
Journal of Thrombosis and Haemostasis 19 (1), 262-268, 2021
72021
Oligonucleotide therapeutics for age-related musculoskeletal disorders: Successes and challenges
TA Nicholson, M Sagmeister, SN Wijesinghe, H Farah, RS Hardy, ...
Pharmaceutics 15 (1), 237, 2023
42023
The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence
SN Wijesinghe, J Anderson, TJ Brown, DE Nanus, B Housmans, ...
Frontiers in Molecular Biosciences 9, 971621, 2022
42022
Long Non-coding RNAs in Rheumatology
SN Wijesinghe, MA Lindsay, SW Jones
Long Noncoding RNA: Mechanistic Insights and Roles in Inflammation, 35-70, 2022
22022
Oligonucleotide therapies in the treatment of inflammatory joint disease
SN Wijesinghe, MA Lindsay, SW Jones
Preprints, 2021
22021
Obese synovial fibroblasts exhibit single cell subsets with specific pathological inflammatory functions in osteoarthritis patients
SN Wijesinghe, A Badoume, DE Nanus, ET Davis, MA Lindsay, SW Jones
Osteoarthritis and Cartilage 28, S84, 2020
22020
Oligonucleotide Therapeutics for Age-Related Musculoskeletal Disorders
TA Nicholson, M Sagmeister, SN Wijesinghe, H Farah, RS Hardy, ...
12023
Identification of synovial fibroblasts subsets associated with pain and progression of knee osteoarthritis by single cell sequencing
DE Nanus, A Badoume, SN Wijesinghe, P Hurley, ET Davis, MA Lindsay, ...
Osteoarthritis and Cartilage 28, S133, 2020
12020
The combination of local infiltration analgesia reagents increases their detrimental effect on human hip OA patient osteoblast viability and function
P Hurley, F Alnajjar, S Wijesinghe, DE Nanus, ET Davis, SW Jones
Journal of Orthopaedics 16 (5), 434-439, 2019
12019
Cross-species transcriptomics and machine learning identifies conserved obesity associated genes in osteoarthritic joint tissues
SN Wijesinghe, A Acharjee, D Russ, G Gkoutos, SW Jones
Osteoarthritis and Cartilage 32, S466-S467, 2024
2024
Specific sites of patient-reported joint pain coincide with presence of bone marrow lesions in knee osteoarthritis patients
SN Wijesinghe, R Botchu, AV Sardeli, CN Ditchfield, ET Davies, ...
Osteoarthritis and Cartilage 32, S509-S510, 2024
2024
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