A single autoimmune T cell receptor recognizes more than a million different peptides L Wooldridge, J Ekeruche-Makinde, H Van Den Berg, A Skowera, ... Journal of Biological Chemistry 287 (2), 1168-1177, 2012 | 497 | 2012 |
Identification in 2 Independent Samples of a Novel Schizophrenia RiskHaplotype of the Dystrobrevin Binding Protein Gene (DTNBP1) NM Williams, A Preece, DW Morris, G Spurlock, NJ Bray, M Stephens, ... Archives of general psychiatry 61 (4), 336-344, 2004 | 249 | 2004 |
The NF-κB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target S Hewamana, S Alghazal, TT Lin, M Clement, C Jenkins, ML Guzman, ... Blood, The Journal of the American Society of Hematology 111 (9), 4681-4689, 2008 | 226 | 2008 |
Interleukin‐6 limits influenza‐induced inflammation and protects against fatal lung pathology SN Lauder, E Jones, K Smart, A Bloom, AS Williams, JP Hindley, ... European journal of immunology 43 (10), 2613-2625, 2013 | 187 | 2013 |
Profound inhibition of antigen-specific T-cell effector functions by dasatinib R Weichsel, C Dix, L Wooldridge, M Clement, A Fenton-May, AK Sewell, ... Clinical Cancer Research 14 (8), 2484-2491, 2008 | 175 | 2008 |
Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition DK Cole, ESJ Edwards, KK Wynn, M Clement, JJ Miles, K Ladell, ... The Journal of Immunology 185 (4), 2600-2610, 2010 | 157 | 2010 |
Escape from highly effective public CD8+ T-cell clonotypes by HIV MC Iglesias, JR Almeida, S Fastenackels, DJ van Bockel, M Hashimoto, ... Blood, The Journal of the American Society of Hematology 118 (8), 2138-2149, 2011 | 131 | 2011 |
ERK is integral to the IFN-γ–mediated activation of STAT1, the expression of key genes implicated in atherosclerosis, and the uptake of modified lipoproteins by human macrophages N Li, JE McLaren, DR Michael, M Clement, CA Fielding, DP Ramji The Journal of Immunology 185 (5), 3041-3048, 2010 | 119 | 2010 |
Peptide length determines the outcome of TCR/peptide-MHCI engagement J Ekeruche-Makinde, JJ Miles, HA Van Den Berg, A Skowera, DK Cole, ... Blood, The Journal of the American Society of Hematology 121 (7), 1112-1123, 2013 | 114 | 2013 |
CD8 controls T cell cross-reactivity L Wooldridge, B Laugel, J Ekeruche, M Clement, HA van den Berg, ... The Journal of Immunology 185 (8), 4625-4632, 2010 | 103 | 2010 |
LY294002 and rapamycin co-operate to inhibit T-cell proliferation EM Breslin, PC White, AM Shore, M Clement, P Brennan British journal of pharmacology 144 (6), 791, 2005 | 86 | 2005 |
The molecular determinants of CD 8 co‐receptor function DK Cole, B Laugel, M Clement, DA Price, L Wooldridge, AK Sewell Immunology 137 (2), 139-148, 2012 | 81 | 2012 |
T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting J Ekeruche-Makinde, M Clement, DK Cole, ESJ Edwards, K Ladell, ... Journal of Biological Chemistry 287 (44), 37269-37281, 2012 | 71 | 2012 |
Regulation of cyclin D2 and the cyclin D2 promoter by protein kinase A and CREB in lymphocytes PC White, AM Shore, M Clement, J McLaren, I Soeiro, EWF Lam, ... Oncogene 25 (15), 2170-2180, 2006 | 63 | 2006 |
Interferon-induced transmembrane protein 1 restricts replication of viruses that enter cells via the plasma membrane SE Smith, DC Busse, S Binter, S Weston, C Diaz Soria, BM Laksono, ... Journal of virology 93 (6), 10.1128/jvi. 02003-18, 2019 | 61 | 2019 |
Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide–MHCI tetramer staining M Clement, K Ladell, J Ekeruche-Makinde, JJ Miles, ESJ Edwards, ... The Journal of Immunology 187 (2), 654-663, 2011 | 55 | 2011 |
The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis MA Stacey, S Clare, M Clement, M Marsden, J Abdul-Karim, L Kane, ... The Journal of clinical investigation 127 (4), 1463-1474, 2017 | 53 | 2017 |
Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence M Clement, M Marsden, MA Stacey, J Abdul-Karim, S Gimeno Brias, ... PLoS Pathogens 12 (12), e1006050, 2016 | 52 | 2016 |
Naive CD8+ T‐cell precursors display structured TCR repertoires and composite antigen‐driven selection dynamics MA Neller, K Ladell, JE McLaren, KK Matthews, E Gostick, JM Pentier, ... Immunology and cell biology 93 (7), 625-633, 2015 | 51 | 2015 |
The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cells B Laugel, DK Cole, M Clement, L Wooldridge, DA Price, AK Sewell Journal of leukocyte biology 90 (6), 1089-1099, 2011 | 47 | 2011 |