| SUMO: a history of modification RT Hay Molecular cell 18 (1), 1-12, 2005 | 2110 | 2005 |
| SUMO-1 modification of IκBα inhibits NF-κB activation JMP Desterro, MS Rodriguez, RT Hay Molecular cell 2 (2), 233-239, 1998 | 1382 | 1998 |
| Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9 MH Tatham, E Jaffray, OA Vaughan, JMP Desterro, CH Botting, ... Journal of Biological Chemistry 276 (38), 35368-35374, 2001 | 1042 | 2001 |
| Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62 JR Matthews, N Wakasugi, JL Virelizier, J Yodoi, RT Hay Nucleic acids research 20 (15), 3821-3830, 1992 | 1034 | 1992 |
| RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation MH Tatham, MC Geoffroy, L Shen, A Plechanovova, N Hattersley, ... Nature cell biology 10 (5), 538-546, 2008 | 978 | 2008 |
| SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting MS Rodriguez, C Dargemont, RT Hay Journal of Biological Chemistry 276 (16), 12654-12659, 2001 | 977 | 2001 |
| SUMO‐1 modification activates the transcriptional response of p53 MS Rodriguez, JMP Desterro, S Lain, CA Midgley, DP Lane, RT Hay The EMBO journal, 1999 | 842 | 1999 |
| Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity DP Xirodimas, MK Saville, JC Bourdon, RT Hay, DP Lane Cell 118 (1), 83-97, 2004 | 719 | 2004 |
| Nuclear localization of IκBα promotes active transport of NF-κB from the nucleus to the cytoplasm F Arenzana-Seisdedos, P Turpin, M Rodriguez, D Thomas, RT Hay, ... Journal of cell science 110 (3), 369-378, 1997 | 673 | 1997 |
| Inducible nuclear expression of newly synthesized IκBα negatively regulates DNA-binding and transcriptional activities of NF-κB F Arenzana-Seisdedos, J Thompson, MS Rodriguez, F Bachelerie, ... Molecular and cellular biology 15 (5), 2689-2696, 1995 | 661 | 1995 |
| Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis A Plechanovová, EG Jaffray, MH Tatham, JH Naismith, RT Hay Nature 489 (7414), 115-120, 2012 | 598 | 2012 |
| Inhibition of NF-κB DNA binding by nitric oxide JR Matthews, CH Botting, M Panico, HR Morris, RT Hay Nucleic acids research 24 (12), 2236-2242, 1996 | 593 | 1996 |
| System-wide changes to SUMO modifications in response to heat shock F Golebiowski, I Matic, MH Tatham, C Cole, Y Yin, A Nakamura, J Cox, ... Science signaling 2 (72), ra24-ra24, 2009 | 574 | 2009 |
| P300 transcriptional repression is mediated by SUMO modification D Girdwood, D Bumpass, OA Vaughan, A Thain, LA Anderson, ... Molecular cell 11 (4), 1043-1054, 2003 | 565 | 2003 |
| Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation MS Rodriguez, JMP Desterro, S Lain, DP Lane, RT Hay Molecular and cellular biology 20 (22), 8458-8467, 2000 | 543 | 2000 |
| Family-wide analysis of poly (ADP-ribose) polymerase activity S Vyas, I Matic, L Uchima, J Rood, R Zaja, RT Hay, I Ahel, P Chang Nature communications 5 (1), 4426, 2014 | 513 | 2014 |
| Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1 JMP Desterro, MS Rodriguez, GD Kemp, RT Hay Journal of Biological Chemistry 274 (15), 10618-10624, 1999 | 486 | 1999 |
| Ubch9 conjugates SUMO but not ubiquitin JMP Desterro, J Thomson, RT Hay FEBS letters 417 (3), 297-300, 1997 | 480 | 1997 |
| Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IκBα E Cabannes, G Khan, F Aillet, RF Jarrett, RT Hay Oncogene 18 (20), 3063-3070, 1999 | 470 | 1999 |
| SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1 T Bouras, M Fu, AA Sauve, F Wang, AA Quong, ND Perkins, RT Hay, ... Journal of Biological Chemistry 280 (11), 10264-10276, 2005 | 429 | 2005 |
