Ioscani Jimenez del Val
Ioscani Jimenez del Val
Assistant Professor (Lecturer) in Bioprocess Engineering, School of Chemical & Bioprocess
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Cited by
Cited by
Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns
IJ Del Val, C Kontoravdi, JM Nagy
Biotechnology progress 26 (6), 1505-1527, 2010
Amino acid and glucose metabolism in fed‐batch CHO cell culture affects antibody production and glycosylation
Y Fan, I Jimenez Del Val, C Müller, J Wagtberg Sen, SK Rasmussen, ...
Biotechnology and bioengineering 112 (3), 521-535, 2015
A dynamic mathematical model for monoclonal antibody N‐linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus
I Jimenez del Val, JM Nagy, C Kontoravdi
Biotechnology progress, 2011
Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylation
PM Jedrzejewski, IJ Del Val, A Constantinou, A Dell, SM Haslam, ...
International journal of molecular sciences 15 (3), 4492-4522, 2014
An optimized method for extraction and quantification of nucleotides and nucleotide sugars from mammalian cells
IJ del Val, S Kyriakopoulos, KM Polizzi, C Kontoravdi
Analytical biochemistry 443 (2), 172-180, 2013
A multi‐pronged investigation into the effect of glucose starvation and culture duration on fed‐batch CHO cell culture
Y Fan, I Jimenez Del Val, C Müller, AM Lund, JW Sen, SK Rasmussen, ...
Biotechnology and bioengineering 112 (10), 2172-2184, 2015
Metabolic network reconstruction: advances in in silico interpretation of analytical information
N Chen, IJ del Val, S Kyriakopoulos, KM Polizzi, C Kontoravdi
Current opinion in biotechnology 23 (1), 77-82, 2012
Dynamics of immature mAb glycoform secretion during CHO cell culture: An integrated modelling framework
I Jimenez del Val, Y Fan, D Weilguny
Biotechnology Journal 11 (5), 610-623, 2016
Integration of models and experimentation to optimise the production of potential biotherapeutics
KE Royle, IJ del Val, C Kontoravdi
Drug discovery today 18 (23-24), 1250-1255, 2013
Activity of NiW catalysts supported on TiO2-Al2O3 mixed oxides: Effect of Ti incorporation method on the HDS of 4, 6-DMDBT
A Gutiérrez-Alejandre, J Ramírez, I Jiménez-del Val, M Peñuelas-Galaz, ...
Catalysis today 107, 879-884, 2005
A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation
IJ Del Val, KM Polizzi, C Kontoravdi
Scientific reports 6, 28547, 2016
Global sensitivity analysis and meta-modeling of an ethanol production process
E Todri, AN Amenaghawon, IJ Del Val, DJ Leak, C Kontoravdi, ...
Chemical Engineering Science 114, 114-127, 2014
Applying quality by design to glycoprotein therapeutics: experimental and computational efforts of process control
PMJ Jedrzejewski, IJ del Val, KM Polizzi, C Kontoravdi
Pharmaceutical Bioprocessing 1 (1), 51-69, 2013
Model‐based optimization of antibody galactosylation in CHO cell culture
P Kotidis, P Jedrzejewski, SN Sou, C Sellick, K Polizzi, IJ del Val, ...
Biotechnology and bioengineering 116 (7), 1612-1626, 2019
Application of quality by design paradigm to the manufacture of protein therapeutics
IJ del Val, PM Jedrzejewski, K Exley, SN Sou, S Kyriakopoulos, ...
Glycosylation, 2012
A quantitative and mechanistic model for monoclonal antibody glycosylation as a function of nutrient availability during cell culture
IJ del Val, A Constantinou, A Dell, S Haslam, KM Polizzi, C Kontoravdi
BMC proceedings 7 (S6), O10, 2013
Electronic structure of transition metal fluorides and oxides determined by resonant X-ray absorption and X-ray emission spectroscopies
J Jiménez-Mier, GM Herrera-Pérez, P Olalde-Velasco, E Chavira, ...
Radiation Effects & Defects in Solids 162 (7-8), 613-620, 2007
Computational tools for predicting and controlling the glycosylation of biopharmaceuticals
C Kontoravdi, IJ del Val
Current opinion in chemical engineering 22, 89-97, 2018
Study of the electronic structure of transition metal compounds by absorption and emission of X-rays
J Jiménez-Mier, G Herrera-Pérez, P Olalde-Velasco, E Chavira, ...
Revista mexicana de física 53, 38-42, 2007
Assessment of the interactions between bioprocess conditions and protein glycosylation in antibody-producing mammalian cell cultures
I Jimenez Del Val
Imperial College London, 2013
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