J.Wade Harper
J.Wade Harper
Professor of Cell Biology
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
70232016
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
JW Harper, GR Adami, N Wei, K Keyomarsi, SJ Elledge
Cell 75 (4), 805-816, 1993
68971993
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
WS El-Deiry, JW Harper, PM O'Connor, VE Velculescu, CE Canman, ...
Cancer research 54 (5), 1169-1174, 1994
27021994
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
C Deng, P Zhang, JW Harper, SJ Elledge, P Leder
Cell 82 (4), 675-684, 1995
23831995
A map of the interactome network of the metazoan C. elegans
S Li, CM Armstrong, N Bertin, H Ge, S Milstein, M Boxem, PO Vidalain, ...
Science 303 (5657), 540-543, 2004
20092004
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
V Dulić, WK Kaufmann, SJ Wilson, TD Tisty, E Lees, JW Harper, ...
Cell 76 (6), 1013-1023, 1994
17561994
The DNA damage response: ten years after
JW Harper, SJ Elledge
Molecular cell 28 (5), 739-745, 2007
17202007
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
C Bai, P Sen, K Hofmann, L Ma, M Goebl, JW Harper, SJ Elledge
Cell 86 (2), 263-274, 1996
15721996
Structure of the Cul1–Rbx1–Skp1–F box Skp2 SCF ubiquitin ligase complex
N Zheng, BA Schulman, L Song, JJ Miller, PD Jeffrey, P Wang, C Chu, ...
Nature 416 (6882), 703-709, 2002
14632002
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
D Skowyra, KL Craig, M Tyers, SJ Elledge, JW Harper
Cell 91 (2), 209-219, 1997
13381997
Network organization of the human autophagy system
C Behrends, ME Sowa, SP Gygi, JW Harper
Nature 466 (7302), 68-76, 2010
13132010
Defining the human deubiquitinating enzyme interaction landscape
ME Sowa, EJ Bennett, SP Gygi, JW Harper
Cell 138 (2), 389-403, 2009
13052009
Systematic and quantitative assessment of the ubiquitin-modified proteome
W Kim, EJ Bennett, EL Huttlin, A Guo, J Li, A Possemato, ME Sowa, ...
Molecular cell 44 (2), 325-340, 2011
12732011
Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle
A Koff, A Giordano, D Desai, K Yamashita, JW Harper, S Elledge, ...
Science 257 (5077), 1689-1694, 1992
12591992
p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
S Matsuoka, MC Edwards, C Bai, S Parker, P Zhang, A Baldini, JW Harper, ...
Genes & development 9 (6), 650-662, 1995
11881995
Inhibition of cyclin-dependent kinases by p21.
JW Harper, SJ Elledge, K Keyomarsi, B Dynlacht, LH Tsai, P Zhang, ...
Molecular biology of the cell 6 (4), 387-400, 1995
11731995
p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells
SB Parker, G Eichele, P Zhang, A Rawls, AT Sands, A Bradley, EN Olson, ...
Science 267 (5200), 1024-1027, 1995
11721995
The SCFβ-TRCP–ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IκBα and β-catenin and stimulates IκBα ubiquitination in vitro
JT Winston, P Strack, P Beer-Romero, CY Chu, SJ Elledge, JW Harper
Genes & development 13 (3), 270-283, 1999
10061999
The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase
SB Cullinan, JD Gordan, J Jin, JW Harper, JA Diehl
Molecular and cellular biology 24 (19), 8477-8486, 2004
8562004
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase
T Kamura, DM Koepp, MN Conrad, D Skowyra, RJ Moreland, O Iliopoulos, ...
Science 284 (5414), 657-661, 1999
8481999
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