Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements MW Coolen, AL Statham, M Gardiner-Garden, SJ Clark Nucleic acids research 35 (18), e119, 2007 | 265 | 2007 |
Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias SS Nair, MW Coolen, C Stirzaker, JZ Song, AL Statham, D Strbenac, ... Epigenetics 6 (1), 34-44, 2011 | 246 | 2011 |
Differential contribution of the three Aph1 genes to γ-secretase activity in vivo L Serneels, T Dejaegere, K Craessaerts, K Horré, E Jorissen, T Tousseyn, ... Proceedings of the National Academy of Sciences 102 (5), 1719-1724, 2005 | 244 | 2005 |
Regional activation of the cancer genome by long-range epigenetic remodeling SA Bert, MD Robinson, D Strbenac, AL Statham, JZ Song, T Hulf, ... Cancer cell 23 (1), 9-22, 2013 | 227 | 2013 |
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity MW Coolen, C Stirzaker, JZ Song, AL Statham, Z Kassir, CS Moreno, ... Nature cell biology 12 (3), 235-246, 2010 | 214 | 2010 |
Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA AL Statham, MD Robinson, JZ Song, MW Coolen, C Stirzaker, SJ Clark Genome research 22 (6), 1120-1127, 2012 | 209 | 2012 |
Repitools: an R package for the analysis of enrichment-based epigenomic data AL Statham, D Strbenac, MW Coolen, C Stirzaker, SJ Clark, MD Robinson Bioinformatics 26 (13), 1662-1663, 2010 | 181 | 2010 |
Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias, and copy number variation MD Robinson, C Stirzaker, AL Statham, MW Coolen, JZ Song, SS Nair, ... Genome research 20 (12), 1719-1729, 2010 | 145 | 2010 |
Regulatory roles for long ncRNA and mRNA AR Karapetyan, C Buiting, RA Kuiper, MW Coolen Cancers 5 (2), 462-490, 2013 | 111 | 2013 |
Impact of the genome on the epigenome is manifested in DNA methylation patterns of imprinted regions in monozygotic and dizygotic twins MW Coolen, AL Statham, W Qu, MJ Campbell, AK Henders, ... PLoS One 6 (10), e25590, 2011 | 94 | 2011 |
Epigenetic deregulation across chromosome 2q14. 2 differentiates normal from prostate cancer and provides a regional panel of novel DNA methylation cancer biomarkers J Devaney, C Stirzaker, W Qu, JZ Song, AL Statham, KI Patterson, ... Cancer epidemiology, biomarkers & prevention 20 (1), 148-159, 2011 | 65 | 2011 |
Noradrenergic activation of the basolateral amygdala maintains hippocampus-dependent accuracy of remote memory E Atucha, V Vukojevic, RV Fornari, G Ronzoni, P Demougin, F Peter, ... Proceedings of the National Academy of Sciences 114 (34), 9176-9181, 2017 | 63 | 2017 |
Dietary methyl donor deficiency during pregnancy in rats shapes learning and anxiety in offspring G Konycheva, MA Dziadek, LR Ferguson, CU Krägeloh, MW Coolen, ... Nutrition Research 31 (10), 790-804, 2011 | 61 | 2011 |
Gene dosage effect on γ-secretase component Aph-1b in a rat model for neurodevelopmental disorders MW Coolen, KMJ Van Loo, NNHM Van Bakel, DJ Pulford, L Serneels, ... Neuron 45 (4), 497-503, 2005 | 53 | 2005 |
Analysis of three Ptx2 splice variants on transcriptional activity and differential expression pattern in the brain MP Smidt, JJ Cox, HSA Schaick, M Coolen, J Schepers, AM Kleij, ... Journal of neurochemistry 75 (5), 1818-1825, 2000 | 53 | 2000 |
Evidence that Brain-Derived Neurotrophic Factor Acts as an Autocrine Factor on Pituitary Melanotrope Cells of Xenopus laevis BMR Kramer, PMJM Cruijsen, DTWM Ouwens, MW Coolen, GJM Martens, ... Endocrinology 143 (4), 1337-1345, 2002 | 51 | 2002 |
HLA and other host factors in transfusion-acquired HIV-1 infection AF Geczy, H Kuipers, M Coolen, LJ Ashton, C Kennedy, G Ng, R Dodd, ... Human Immunology 61 (2), 172-176, 2000 | 30 | 2000 |
Reduced Aph‐1b expression causes tissue‐and substrate‐specific changes in γ‐secretase activity in rats with a complex phenotype MW Coolen, KMJ van Loo, NNHM van Bakel, BA Ellenbroek, AR Cools, ... The FASEB journal 20 (1), 175-177, 2006 | 29 | 2006 |
Correlates of antiviral immune restoration in acute and chronic HIV type 1 infection: sustained viral suppression and normalization of T cell subsets WB Dyer, H Kuipers, MW Coolen, AF Geczy, J Forrester, C Workman, ... AIDS research and human retroviruses 18 (14), 999-1010, 2002 | 23 | 2002 |
GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association ME Rentería, MW Coolen, AL Statham, RSM Choi, W Qu, MJ Campbell, ... Twin Research and Human Genetics 16 (4), 767-781, 2013 | 12 | 2013 |