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Paolo Paganetti
Paolo Paganetti
Laboratories for Translational Research, Ente Ospedaliero Cantonale
Verified email at eoc.ch - Homepage
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13347*2021
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
C Sturchler-Pierrat, D Abramowski, M Duke, KH Wiederhold, C Mistl, ...
Proceedings of the National Academy of Sciences 94 (24), 13287-13292, 1997
18761997
Exogenous induction of cerebral ß-amyloidogenesis is governed by agent and host
M Meyer-Luehmann, J Coomaraswamy, T Bolmont, S Kaeser, C Schaefer, ...
Science 313 (5794), 1781-1784, 2006
11092006
Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle
M Molinari, V Calanca, C Galli, P Lucca, P Paganetti
Science 299 (5611), 1397-1400, 2003
5982003
Acetylation targets mutant huntingtin to autophagosomes for degradation
H Jeong, F Then, TJ Melia, JR Mazzulli, L Cui, JN Savas, C Voisine, ...
Cell 137 (1), 60-72, 2009
4802009
Amyloid β interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease
A Lorenzo, M Yuan, Z Zhang, PA Paganetti, C Sturchler-Pierrat, ...
Nature neuroscience 3 (5), 460-464, 2000
3762000
Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease
C Landles, K Sathasivam, A Weiss, B Woodman, H Moffitt, S Finkbeiner, ...
Journal of Biological Chemistry 285 (12), 8808-8823, 2010
3492010
Membrane-type 1 matrix metalloprotease (MT1-MMP) enables invasive migration of glioma cells in central nervous system white matter
ATJ Beliën, PA Paganetti, ME Schwab
The Journal of cell biology 144 (2), 373-384, 1999
2941999
Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation
T Afroz, EM Hock, P Ernst, C Foglieni, M Jambeau, LAB Gilhespy, ...
Nature communications 8 (1), 45, 2017
2682017
Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER
M Molinari, C Galli, V Piccaluga, M Pieren, P Paganetti
The Journal of cell biology 158 (2), 247-257, 2002
2632002
The carboxyl termini of β-amyloid peptides 1-40 and 1-42 are generated by distinct γ-secretase activities
HW Klafki, D Abramowski, R Swoboda, PA Paganetti, M Staufenbiel
Journal of Biological Chemistry 271 (45), 28655-28659, 1996
2321996
EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation
S Olivari, T Cali, KEH Salo, P Paganetti, LW Ruddock, M Molinari
Biochemical and biophysical research communications 349 (4), 1278-1284, 2006
2232006
Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease
J Labbadia, H Cunliffe, A Weiss, E Katsyuba, K Sathasivam, T Seredenina, ...
The Journal of clinical investigation 121 (8), 3306-3319, 2011
2002011
Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease
K Sathasivam, A Lane, J Legleiter, A Warley, B Woodman, S Finkbeiner, ...
Human molecular genetics 19 (1), 65-78, 2010
1722010
Expression of human β‐secretase in the mouse brain increases the steady‐state level of β‐amyloid
U Bodendorf, S Danner, F Fischer, M Stefani, C Sturchler‐Pierrat, ...
Journal of neurochemistry 80 (5), 799-806, 2002
1722002
ER‐to‐lysosome‐associated degradation of proteasome‐resistant ATZ polymers occurs via receptor‐mediated vesicular transport
I Fregno, E Fasana, TJ Bergmann, A Raimondi, M Loi, T Soldà, C Galli, ...
The EMBO journal 37 (17), e99259, 2018
1602018
Targeting presenilin-type aspartic protease signal peptide peptidase with γ-secretase inhibitors
A Weihofen, MK Lemberg, E Friedmann, H Rueeger, A Schmitz, ...
Journal of Biological Chemistry 278 (19), 16528-16533, 2003
1542003
BACE (β-secretase) modulates the processing of APLP2 in vivo
L Pastorino, AF Ikin, S Lamprianou, N Vacaresse, JP Revelli, K Platt, ...
Molecular and Cellular Neuroscience 25 (4), 642-649, 2004
1492004
Suppression of protein aggregation by chaperone modification of high molecular weight complexes
J Labbadia, SS Novoselov, JS Bett, A Weiss, P Paganetti, GP Bates, ...
Brain 135 (4), 1180-1196, 2012
1392012
Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression
MA Pouladi, Y Xie, NH Skotte, DE Ehrnhoefer, RK Graham, JE Kim, ...
Human molecular genetics 19 (8), 1528-1538, 2010
1392010
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