Ieva Drulyte

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Daniel L. HurdissAssistant Professor, Utrecht UniversityVerified email at uu.nl
Frank van Kuppeveldhoogleraar virologieVerified email at uu.nl
Berend Jan BoschVirology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The NetherlandsVerified email at uu.nl
Rachel JohnsonMonash UniversityVerified email at monash.edu
Joost SnijderUtrecht UniversityVerified email at uu.nl
Wentao LiProfessor. College of Veterinary Medicine, Huazhong Agricultural UniversityVerified email at mail.hzau.edu.cn
Friedrich FörsterProfessor, Utrecht UniversityVerified email at uu.nl
juliette fedryMRC - Laboratory of Molecular BiologyVerified email at mrc-lmb.cam.ac.uk
Rebecca ThompsonThermo Fisher ScientificVerified email at thermofisher.com
Charlotte (Charlie) Anne ScarffBHF Intermediate Fellow, University of LeedsVerified email at leeds.ac.uk
Neil A RansonAstbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University ofVerified email at leeds.ac.uk
Emma HeskethCryoEM Facility Manager, University of Leicester, Leicester, LE1 7RHVerified email at leicester.ac.uk
stephen muenchAssociate professor, University of LeedsVerified email at leeds.ac.uk
Sebastian Alin PoravResearch assistant, National Institute for Research and Development of Isotopic and MolecularVerified email at itim-cj.ro
Matti F. PronkerUtrecht UniversityVerified email at xs4all.nl
Patrick SextonMonash UniversityVerified email at monash.edu
Denise WoottenMonash Institute of Pharmaceutical SciencesVerified email at monash.edu
Matthew BelousoffMonash University, Monash Institute of Pharmaceutical SciencesVerified email at monash.edu
Abhay KotechaThermo Fisher ScientificVerified email at thermofisher.com
Radostin DanevThe University of TokyoVerified email at biochem.mpg.de

Ieva Drulyte

Thermo Fisher Scientific

Verified email at thermofisher.com

Cryo-EM Structural Biology


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Approaches to altering particle distributions in cryo-electron microscopy sample preparation I Drulyte, RM Johnson, EL Hesketh, DL Hurdiss, CA Scarff, SA Porav, ... Acta Crystallographica Section D: Structural Biology 74 (6), 560-571, 2018	153	2018
The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants S Rothenberger, DL Hurdiss, M Walser, F Malvezzi, J Mayor, S Ryter, ... Nature biotechnology 40 (12), 1845-1854, 2022	53*	2022
Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11 J Fedry, DL Hurdiss, C Wang, W Li, G Obal, I Drulyte, W Du, SC Howes, ... Science advances 7 (23), eabf5632, 2021	43*	2021
An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern W Du, DL Hurdiss, D Drabek, AZ Mykytyn, FK Kaiser, ... Science immunology 7 (73), eabp9312, 2022	38	2022
Evolving cryo-EM structural approaches for GPCR drug discovery X Zhang, RM Johnson, I Drulyte, L Yu, A Kotecha, R Danev, D Wootten, ... Structure 29 (9), 963-974. e6, 2021	38	2021
Highly potent anti-SARS-CoV-2 multi-DARPin therapeutic candidates M Walser, S Rothenberger, DL Hurdiss, A Schlegel, V Calabro, ... Biorxiv, 2020.08. 25.256339, 2020	38	2020
Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans DL Hurdiss, I Drulyte, Y Lang, TM Shamorkina, MF Pronker, ... Nature Communications 11 (1), 4646, 2020	31	2020
Sialoglycan binding triggers spike opening in a human coronavirus MF Pronker, R Creutznacher, I Drulyte, RJG Hulswit, Z Li, ... Nature 624 (7990), 201-206, 2023	14	2023
Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase I Drulyte, J Obajdin, CH Trinh, AP Kalverda, MW Van der Kamp, ... IUCrJ 6 (6), 1120-1133, 2019	9	2019
A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein V Thijssen, DL Hurdiss, OJ Debski-Antoniak, MA Spence, C Franck, ... Proceedings of the National Academy of Sciences 120 (26), e2303292120, 2023	7	2023
Direct cell extraction of membrane proteins for structure–function analysis I Drulyte, AR Gutgsell, P Lloris-Garcerá, M Liss, S Geschwindner, ... Scientific Reports 13 (1), 1420, 2023	4	2023
High-throughput cryo-EM epitope mapping of SARS-CoV-2 spike protein antibodies using EPU Multigrid I Drulyte, S Koester, D Lundberg, K Eng, A Malyutin, BJB Kuppeveld, ... Thermo Fisher Scientific White Paper, 2022	4	2022
Thermo scientific™ glacios cryo-TEM: a versatile 200 kV tool for structure-based drug discovery I Drulyte, X Zhang, R Johnson, A Koh, S Masiulis, S Unger, E Pechnikova, ... Microscopy and Microanalysis 27 (S1), 3256-3258, 2021	2	2021
Tomo Live: an on-the-fly reconstruction pipeline to judge data quality for cryo-electron tomography workflows M Comet, PM Dijkman, R Boer Iwema, T Franke, S Masiulis, R Schampers, ... Acta Crystallographica Section D: Structural Biology 80 (4), 2024		2024
Neutralizing Antibodies Reveal Cryptic Vulnerabilities and Interdomain Crosstalk in the Porcine Deltacoronavirus Spike BJ Bosch, W Du, O Debski-Antoniak, D Drabek, R van Haperen, ...		2024
Structural basis for inhibition of βFXIIa by garadacimab I Drulyte, R Ghai, SY Ow, E Kapp, A Quek, C Panousis, MJ Wilson, ... bioRxiv, 2023.12. 03.569829, 2023		2023
Structural and Functional Studies of Polyketide Synthases I Drulyte University of Leeds, 2018		2018
Cryo-EM structure of channel pannexin 1 using GeneArt and Salipro DirectMX platforms I Drulyte, P Lloris-Garcerá, M Liss, R Loving, J Frauenfeld, M Radjainia

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