| Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells GT Hess, L Frésard, K Han, CH Lee, A Li, KA Cimprich, SB Montgomery, ... Nature methods 13 (12), 1036-1042, 2016 | 494 | 2016 |
| Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions K Han, EE Jeng, GT Hess, DW Morgens, A Li, MC Bassik Nature biotechnology 35 (5), 463-474, 2017 | 485 | 2017 |
| Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens DW Morgens, M Wainberg, EA Boyle, O Ursu, CL Araya, CK Tsui, ... Nature communications 8 (1), 15178, 2017 | 335 | 2017 |
| SLC19A1 is an importer of the immunotransmitter cGAMP C Ritchie, AF Cordova, GT Hess, MC Bassik, L Li Molecular cell 75 (2), 372-381. e5, 2019 | 263 | 2019 |
| Methods and applications of CRISPR-mediated base editing in eukaryotic genomes GT Hess, J Tycko, D Yao, MC Bassik Molecular cell 68 (1), 26-43, 2017 | 260 | 2017 |
| Static and dynamic DNA loops form AP-1-bound activation hubs during macrophage development DH Phanstiel, K Van Bortle, D Spacek, GT Hess, MS Shamim, I Machol, ... Molecular cell 67 (6), 1037-1048. e6, 2017 | 260 | 2017 |
| The impact of rare variation on gene expression across tissues X Li, Y Kim, EK Tsang, JR Davis, FN Damani, C Chiang, GT Hess, ... Nature 550 (7675), 239-243, 2017 | 258 | 2017 |
| A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies DK Breslow, S Hoogendoorn, AR Kopp, DW Morgens, BK Vu, ... Nature genetics 50 (3), 460-471, 2018 | 155 | 2018 |
| M13 bacteriophage display framework that allows sortase-mediated modification of surface-accessible phage proteins GT Hess, JJ Cragnolini, MW Popp, MA Allen, SK Dougan, E Spooner, ... Bioconjugate chemistry 23 (7), 1478-1487, 2012 | 128 | 2012 |
| The LRRC8A: C heteromeric channel is a cGAMP transporter and the dominant cGAMP importer in human vasculature cells LJ Lahey, X Wen, RE Mardjuki, V Böhnert, C Ritchie, JA Carozza, ... BioRxiv, 2020.02. 13.948273, 2020 | 123* | 2020 |
| Transcriptomic signatures across human tissues identify functional rare genetic variation NM Ferraro, BJ Strober, J Einson, NS Abell, F Aguet, AN Barbeira, ... Science 369 (6509), eaaz5900, 2020 | 115 | 2020 |
| Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements J Tycko, M Wainberg, GK Marinov, O Ursu, GT Hess, BK Ego, Aradhana, ... Nature communications 10 (1), 4063, 2019 | 104 | 2019 |
| Translation readthrough mitigation JA Arribere, ES Cenik, N Jain, GT Hess, CH Lee, MC Bassik, AZ Fire Nature 534 (7609), 719-723, 2016 | 101 | 2016 |
| Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7 S Wisnovsky, L Möckl, SA Malaker, K Pedram, GT Hess, NM Riley, ... Proceedings of the National Academy of Sciences 118 (5), e2015024118, 2021 | 86 | 2021 |
| High-throughput discovery and characterization of human transcriptional effectors J Tycko, N DelRosso, GT Hess, A Banerjee, A Mukund, MV Van, BK Ego, ... Cell 183 (7), 2020 | 73 | 2020 |
| Cellular binding, motion, and internalization of synthetic gene delivery polymers GT Hess, WH Humphries IV, NC Fay, CK Payne Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (10), 1583-1588, 2007 | 63 | 2007 |
| Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation MF Debets, OY Tastan, SP Wisnovsky, SA Malaker, N Angelis, ... Proceedings of the National Academy of Sciences 117 (41), 25293-25301, 2020 | 53 | 2020 |
| Population-and individual-specific regulatory variation in Sardinia M Pala, Z Zappala, M Marongiu, X Li, JR Davis, R Cusano, F Crobu, ... Nature genetics 49 (5), 700-707, 2017 | 52 | 2017 |
| Orthogonal labeling of M13 minor capsid proteins with DNA to self-assemble end-to-end multiphage structures GT Hess, CP Guimaraes, E Spooner, HL Ploegh, AM Belcher ACS synthetic biology 2 (9), 490-496, 2013 | 50 | 2013 |
| Sortase-mediated modification of viral surface proteins HL Ploegh, G Hess, C Guimaraes, A Belcher US Patent App. 13/918,278, 2014 | 24 | 2014 |
