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Douglas Pires
Douglas Pires
Exscientia, School of Computing and Information Systems, The University of Melbourne
Verified email at exscientia.co.uk
Title
Cited by
Cited by
Year
pkCSM: predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures
DEV Pires, TL Blundell, DB Ascher
Journal of medicinal chemistry 58 (9), 4066-4072, 2015
32522015
mCSM: predicting the effects of mutations in proteins using graph-based signatures
DEV Pires, DB Ascher, TL Blundell
Bioinformatics 30 (3), 335-342, 2014
9042014
DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability
CHM Rodrigues, DEV Pires, DB Ascher
Nucleic acids research 46 (W1), W350-W355, 2018
8412018
DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach
DEV Pires, DB Ascher, TL Blundell
Nucleic acids research 42 (W1), W314-W319, 2014
7902014
A structural biology community assessment of AlphaFold2 applications
M Akdel, DEV Pires, EP Pardo, J Jänes, AO Zalevsky, B Mészáros, ...
Nature Structural & Molecular Biology 29 (11), 1056-1067, 2022
3752022
mCSM-PPI2: predicting the effects of mutations on protein–protein interactions
CHM Rodrigues, Y Myung, DEV Pires, DB Ascher
Nucleic acids research 47 (W1), W338-W344, 2019
2782019
DynaMut2: Assessing changes in stability and flexibility upon single and multiple point missense mutations
CHM Rodrigues, DEV Pires, DB Ascher
Protein Science 30 (1), 60-69, 2021
2762021
Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD
KA Andrews, DB Ascher, DEV Pires, DR Barnes, L Vialard, RT Casey, ...
Journal of medical genetics 55 (6), 384-394, 2018
2202018
mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance
DEV Pires, TL Blundell, DB Ascher
Scientific reports 6 (1), 29575, 2016
1322016
Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance
J Phelan, F Coll, R McNerney, DB Ascher, DEV Pires, N Furnham, ...
BMC medicine 14, 1-13, 2016
1172016
mCSM-AB: a web server for predicting antibody–antigen affinity changes upon mutation with graph-based signatures
DEV Pires, DB Ascher
Nucleic acids research 44 (W1), W469-W473, 2016
1162016
CSM-lig: a web server for assessing and comparing protein–small molecule affinities
DEV Pires, DB Ascher
Nucleic acids research 44 (W1), W557-W561, 2016
1082016
Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’in Italy
M Nemethova, J Radvanszky, L Kadasi, DB Ascher, DEV Pires, ...
European Journal of Human Genetics 24 (1), 66-72, 2016
1082016
Protein cutoff scanning: A comparative analysis of cutoff dependent and cutoff free methods for prospecting contacts in proteins
CH da Silveira, DEV Pires, RC Minardi, C Ribeiro, CJM Veloso, ...
Proteins: Structure, Function, and Bioinformatics 74 (3), 727-743, 2009
1052009
mCSM–NA: predicting the effects of mutations on protein–nucleic acids interactions
DEV Pires, DB Ascher
Nucleic acids research 45 (W1), W241-W246, 2017
1032017
Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma
M Jafri, NC Wake, DB Ascher, DEV Pires, D Gentle, MR Morris, ...
Cancer discovery 5 (7), 723-729, 2015
1002015
Platinum: a database of experimentally measured effects of mutations on structurally defined protein–ligand complexes
DEV Pires, TL Blundell, DB Ascher
Nucleic acids research 43 (D1), D387-D391, 2015
942015
In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity
DEV Pires, J Chen, TL Blundell, DB Ascher
Scientific reports 6 (1), 19848, 2016
912016
Cutoff Scanning Matrix (CSM): structural classification and function prediction by protein inter-residue distance patterns
DEV Pires, RC de Melo-Minardi, MA dos Santos, CH da Silveira, ...
BMC Genomics 12 (Suppl 4), S12, 2011
862011
Variation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax Relapses
ACR Silvino, GL Costa, FCF Araújo, DB Ascher, DEV Pires, CJF Fontes, ...
PloS one 11 (7), e0160172, 2016
782016
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